55 items (Penicillium expansum) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	PEX2_043970	Succinate dehydrogenase, cytochrome b560 subunit. (188 aa)
	PEX2_101920	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (484 aa)
	PEX2_093840	Citrate synthase; Belongs to the citrate synthase family. (470 aa)
	PEX2_071690	Iso_dh domain-containing protein. (357 aa)
	PEX2_068360	Glutathione-dependent formaldehyde-activating enzyme/centromere protein V. (136 aa)
	PEX2_018800	Isocitrate and isopropylmalate dehydrogenases family. (363 aa)
	PEX2_044960	Major facilitator superfamily domain, general substrate transporter. (533 aa)
	PEX2_035120	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (443 aa)
	PEX2_029580	Citrate synthase-like, core. (655 aa)
	PEX2_085950	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (647 aa)
	PEX2_105620	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (295 aa)
	PEX2_029570	ATP-grasp fold, succinyl-CoA synthetase-type. (485 aa)
	PEX2_038410	Iso_dh domain-containing protein. (564 aa)
	PEX2_083750	Major facilitator superfamily domain, general substrate transporter. (1220 aa)
	PEX2_047610	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (400 aa)
	PEX2_008000	Major facilitator superfamily domain, general substrate transporter. (619 aa)
	PEX2_109880	Major facilitator superfamily domain, general substrate transporter. (465 aa)
	PEX2_064740	Alpha/gamma-adaptin-binding protein p34. (425 aa)
	PEX2_010580	Uncharacterized protein. (248 aa)
	PEX2_096070	Major facilitator superfamily domain, general substrate transporter. (488 aa)
	PEX2_091550	Fumarate lyase. (752 aa)
	PEX2_067500	Uncharacterized protein. (272 aa)
	PEX2_031930	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (405 aa)
	PEX2_051350	Uncharacterized protein. (191 aa)
	PEX2_107270	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (271 aa)
	PEX2_044910	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (334 aa)
	PEX2_105050	Major facilitator superfamily domain, general substrate transporter. (556 aa)
	PEX2_020450	Peripheral subunit-binding (PSBD) domain-containing protein. (289 aa)
	PEX2_074190	Malate dehydrogenase, type 1; Belongs to the LDH/MDH superfamily. (330 aa)
	PEX2_041190	ATP-grasp fold, subdomain 2. (412 aa)
	PEX2_084910	Dihydrolipoyl dehydrogenase. (512 aa)
	PEX2_093190	Ribosome biogenesis protein BMS1/TSR1, C-terminal. (803 aa)
	PEX2_043320	Biotin carboxylase, C-terminal. (668 aa)
	PEX2_015000	Phosphoenolpyruvate carboxykinase, N-terminal. (599 aa)
	PEX2_030060	Dihydrolipoamide succinyltransferase. (557 aa)
	PEX2_051650	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)
	PEX2_051330	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
	PEX2_039520	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (169 aa)
	PEX2_103930	Dehydrogenase, E1 component. (1059 aa)
	PEX2_099380	Major facilitator superfamily domain, general substrate transporter. (424 aa)
	PEX2_100010	Fumarase C, C-terminal. (475 aa)
	PEX2_019390	Uncharacterized protein. (333 aa)
	PEX2_053210	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (783 aa)
	PEX2_022590	Citrate synthase; Belongs to the citrate synthase family. (465 aa)
	PEX2_098400	Major facilitator superfamily domain, general substrate transporter. (490 aa)
	PEX2_034610	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1192 aa)
	PEX2_061880	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
	PEX2_089340	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (920 aa)
	PEX2_030070	Dehydrogenase, E1 component. (961 aa)
	PEX2_037510	Biotin/lipoyl attachment. (455 aa)
	PEX2_084920	Major facilitator superfamily domain, general substrate transporter. (513 aa)
	PEX2_101950	Malate dehydrogenase. (340 aa)
	PEX2_068350	Citrate synthase-like, core. (441 aa)
	PEX2_045950	Uncharacterized protein. (250 aa)
	PEX2_013790	Uncharacterized protein. (252 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_008000	PEX2_015000	A0A0A2JAP1	A0A0A2IDC2	Major facilitator superfamily domain, general substrate transporter.	Phosphoenolpyruvate carboxykinase, N-terminal.	0.418
PEX2_008000	PEX2_053210	A0A0A2JAP1	A0A0A2JU44	Major facilitator superfamily domain, general substrate transporter.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.418
PEX2_008000	PEX2_068350	A0A0A2JAP1	A0A0A2K2Z0	Major facilitator superfamily domain, general substrate transporter.	Citrate synthase-like, core.	0.472
PEX2_010580	PEX2_018800	A0A0A2J7Y0	A0A0A2K6J4	Uncharacterized protein.	Isocitrate and isopropylmalate dehydrogenases family.	0.458
PEX2_010580	PEX2_019390	A0A0A2J7Y0	A0A0A2JZ63	Uncharacterized protein.	Uncharacterized protein.	0.617
PEX2_010580	PEX2_020450	A0A0A2J7Y0	A0A0A2KS29	Uncharacterized protein.	Peripheral subunit-binding (PSBD) domain-containing protein.	0.408
PEX2_010580	PEX2_022590	A0A0A2J7Y0	A0A0A2JSJ7	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.741
PEX2_010580	PEX2_029570	A0A0A2J7Y0	A0A0A2JIF3	Uncharacterized protein.	ATP-grasp fold, succinyl-CoA synthetase-type.	0.631
PEX2_010580	PEX2_029580	A0A0A2J7Y0	A0A0A2KAI7	Uncharacterized protein.	Citrate synthase-like, core.	0.631
PEX2_010580	PEX2_030060	A0A0A2J7Y0	A0A0A2IA41	Uncharacterized protein.	Dihydrolipoamide succinyltransferase.	0.496
PEX2_010580	PEX2_030070	A0A0A2J7Y0	A0A0A2JIL2	Uncharacterized protein.	Dehydrogenase, E1 component.	0.696
PEX2_010580	PEX2_031930	A0A0A2J7Y0	A0A0A2J3P8	Uncharacterized protein.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.475
PEX2_010580	PEX2_034610	A0A0A2J7Y0	A0A0A2JNU1	Uncharacterized protein.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.466
PEX2_010580	PEX2_035120	A0A0A2J7Y0	A0A0A2K8K5	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.672
PEX2_010580	PEX2_037510	A0A0A2J7Y0	A0A0A2I126	Uncharacterized protein.	Biotin/lipoyl attachment.	0.496
PEX2_010580	PEX2_038410	A0A0A2J7Y0	A0A0A2JI45	Uncharacterized protein.	Iso_dh domain-containing protein.	0.458
PEX2_010580	PEX2_039520	A0A0A2J7Y0	A0A0A2I8L7	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit.	0.832
PEX2_010580	PEX2_041190	A0A0A2J7Y0	A0A0A2KWL5	Uncharacterized protein.	ATP-grasp fold, subdomain 2.	0.672
PEX2_010580	PEX2_043970	A0A0A2J7Y0	A0A0A2ILI2	Uncharacterized protein.	Succinate dehydrogenase, cytochrome b560 subunit.	0.833
PEX2_010580	PEX2_044910	A0A0A2J7Y0	A0A0A2KHC0	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.845