13 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	PEX2_084500	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	PEX2_008530	Transcription factor, fungi. (609 aa)
	PEX2_104910	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	PEX2_054560	Transcription factor IIIC, putative zinc-finger. (719 aa)
	PEX2_035560	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (461 aa)
	PEX2_051740	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (544 aa)
	PEX2_063100	Short-chain dehydrogenase/reductase SDR. (317 aa)
	PEX2_021370	Pyruvate carboxyltransferase. (359 aa)
	PEX2_054570	Thiolase, C-terminal; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	PEX2_067440	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (435 aa)
	PEX2_009020	Acetoacetate decarboxylase. (244 aa)
	PEX2_109680	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	PEX2_032360	Short-chain dehydrogenase/reductase SDR. (282 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_008530	PEX2_009020	A0A0A2J937	A0A0A2JGA2	Transcription factor, fungi.	Acetoacetate decarboxylase.	0.779
PEX2_008530	PEX2_021370	A0A0A2J937	A0A0A2K796	Transcription factor, fungi.	Pyruvate carboxyltransferase.	0.764
PEX2_008530	PEX2_032360	A0A0A2J937	A0A0A2J992	Transcription factor, fungi.	Short-chain dehydrogenase/reductase SDR.	0.508
PEX2_008530	PEX2_035560	A0A0A2J937	A0A0A2IP70	Transcription factor, fungi.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.612
PEX2_008530	PEX2_054560	A0A0A2J937	A0A0A2J002	Transcription factor, fungi.	Transcription factor IIIC, putative zinc-finger.	0.669
PEX2_008530	PEX2_054570	A0A0A2J937	A0A0A2JWR7	Transcription factor, fungi.	Thiolase, C-terminal; Belongs to the thiolase-like superfamily. Thiolase family.	0.669
PEX2_008530	PEX2_063100	A0A0A2J937	A0A0A2KR83	Transcription factor, fungi.	Short-chain dehydrogenase/reductase SDR.	0.508
PEX2_008530	PEX2_067440	A0A0A2J937	A0A0A2JS62	Transcription factor, fungi.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.612
PEX2_008530	PEX2_084500	A0A0A2J937	A0A0A2IMQ5	Transcription factor, fungi.	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family.	0.669
PEX2_008530	PEX2_109680	A0A0A2J937	A0A0A2JAE7	Transcription factor, fungi.	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family.	0.669
PEX2_009020	PEX2_008530	A0A0A2JGA2	A0A0A2J937	Acetoacetate decarboxylase.	Transcription factor, fungi.	0.779
PEX2_009020	PEX2_051740	A0A0A2JGA2	A0A0A2KRC4	Acetoacetate decarboxylase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.779
PEX2_009020	PEX2_104910	A0A0A2JGA2	A0A0A2J5B1	Acetoacetate decarboxylase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.779
PEX2_021370	PEX2_008530	A0A0A2K796	A0A0A2J937	Pyruvate carboxyltransferase.	Transcription factor, fungi.	0.764
PEX2_021370	PEX2_035560	A0A0A2K796	A0A0A2IP70	Pyruvate carboxyltransferase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.919
PEX2_021370	PEX2_051740	A0A0A2K796	A0A0A2KRC4	Pyruvate carboxyltransferase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.935
PEX2_021370	PEX2_054560	A0A0A2K796	A0A0A2J002	Pyruvate carboxyltransferase.	Transcription factor IIIC, putative zinc-finger.	0.917
PEX2_021370	PEX2_054570	A0A0A2K796	A0A0A2JWR7	Pyruvate carboxyltransferase.	Thiolase, C-terminal; Belongs to the thiolase-like superfamily. Thiolase family.	0.917
PEX2_021370	PEX2_067440	A0A0A2K796	A0A0A2JS62	Pyruvate carboxyltransferase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.919
PEX2_021370	PEX2_084500	A0A0A2K796	A0A0A2IMQ5	Pyruvate carboxyltransferase.	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family.	0.924