37 items (Penicillium expansum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_073660	CAAX amino terminal protease. (338 aa)
	PEX2_078080	Prenylcysteine oxidase. (544 aa)
	PEX2_060870	Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (370 aa)
	PEX2_005930	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1123 aa)
	PEX2_037220	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1128 aa)
	PEX2_055190	Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (347 aa)
	PEX2_010880	Isopentenyl-diphosphate delta-isomerase, type 1. (270 aa)
	PEX2_015090	Uncharacterized protein. (449 aa)
	PEX2_046330	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (303 aa)
	PEX2_085490	Mitochondrial outer membrane translocase complex, subunit Tom70. (622 aa)
	PEX2_034510	Protein prenyltransferase, alpha subunit. (335 aa)
	PEX2_073430	Uncharacterized protein. (423 aa)
	PEX2_054570	Thiolase, C-terminal; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	PEX2_075640	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (232 aa)
	PEX2_093520	Alkyl transferase; Belongs to the UPP synthase family. (172 aa)
	PEX2_069120	DUF2236 domain-containing protein. (303 aa)
	PEX2_067440	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (435 aa)
	PEX2_005160	Terpenoid synthase. (330 aa)
	PEX2_038440	Terpenoid synthase. (684 aa)
	PEX2_062410	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1007 aa)
	PEX2_107670	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (483 aa)
	PEX2_064850	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (401 aa)
	PEX2_109680	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	PEX2_031900	Peptidase M48. (355 aa)
	PEX2_102830	Uncharacterized protein. (402 aa)
	PEX2_048920	Uncharacterized protein. (356 aa)
	PEX2_087940	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (234 aa)
	PEX2_009270	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (816 aa)
	PEX2_019670	Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (447 aa)
	PEX2_054560	Transcription factor IIIC, putative zinc-finger. (719 aa)
	PEX2_056910	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (456 aa)
	PEX2_084500	Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	PEX2_035560	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (461 aa)
	PEX2_057650	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (404 aa)
	PEX2_034700	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (532 aa)
	PEX2_101790	Ribosomal protein S5 domain 2-type fold, subgroup. (312 aa)
	PEX2_101780	4-diphosphocytidyl-2C-methyl-D-erythritol synthase. (407 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_005160	PEX2_005930	A0A0A2JK86	A0A0A2KJ99	Terpenoid synthase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.472
PEX2_005160	PEX2_010880	A0A0A2JK86	A0A0A2K608	Terpenoid synthase.	Isopentenyl-diphosphate delta-isomerase, type 1.	0.746
PEX2_005160	PEX2_019670	A0A0A2JK86	A0A0A2IAG6	Terpenoid synthase.	Terpenoid synthase; Belongs to the FPP/GGPP synthase family.	0.699
PEX2_005160	PEX2_034510	A0A0A2JK86	A0A0A2K061	Terpenoid synthase.	Protein prenyltransferase, alpha subunit.	0.702
PEX2_005160	PEX2_035560	A0A0A2JK86	A0A0A2IP70	Terpenoid synthase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.460
PEX2_005160	PEX2_037220	A0A0A2JK86	A0A0A2KHD5	Terpenoid synthase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.472
PEX2_005160	PEX2_048920	A0A0A2JK86	A0A0A2J1X3	Terpenoid synthase.	Uncharacterized protein.	0.694
PEX2_005160	PEX2_055190	A0A0A2JK86	A0A0A2KCU1	Terpenoid synthase.	Terpenoid synthase; Belongs to the FPP/GGPP synthase family.	0.810
PEX2_005160	PEX2_057650	A0A0A2JK86	A0A0A2IQJ4	Terpenoid synthase.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.812
PEX2_005160	PEX2_064850	A0A0A2JK86	A0A0A2JBJ0	Terpenoid synthase.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.720
PEX2_005160	PEX2_067440	A0A0A2JK86	A0A0A2JS62	Terpenoid synthase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.460
PEX2_005160	PEX2_069120	A0A0A2JK86	A0A0A2JSH7	Terpenoid synthase.	DUF2236 domain-containing protein.	0.607
PEX2_005160	PEX2_073430	A0A0A2JK86	A0A0A2JX47	Terpenoid synthase.	Uncharacterized protein.	0.526
PEX2_005160	PEX2_093520	A0A0A2JK86	A0A0A2JU79	Terpenoid synthase.	Alkyl transferase; Belongs to the UPP synthase family.	0.636
PEX2_005160	PEX2_102830	A0A0A2JK86	A0A0A2J3S3	Terpenoid synthase.	Uncharacterized protein.	0.694
PEX2_005930	PEX2_005160	A0A0A2KJ99	A0A0A2JK86	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Terpenoid synthase.	0.472
PEX2_005930	PEX2_010880	A0A0A2KJ99	A0A0A2K608	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Isopentenyl-diphosphate delta-isomerase, type 1.	0.688
PEX2_005930	PEX2_019670	A0A0A2KJ99	A0A0A2IAG6	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Terpenoid synthase; Belongs to the FPP/GGPP synthase family.	0.565
PEX2_005930	PEX2_034700	A0A0A2KJ99	A0A0A2IRB1	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.900
PEX2_005930	PEX2_035560	A0A0A2KJ99	A0A0A2IP70	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.945