(58 nodes) Basal transcription factors network (Penicillium expansum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX2_007180	Cdk-activating kinase assembly factor MAT1, centre. (352 aa)
	PEX2_071320	Zinc finger, RanBP2-type. (620 aa)
	PEX2_012230	Helicase-like, DEXD box c2 type. (796 aa)
	PEX2_051590	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (692 aa)
	PEX2_046370	Transcription factor TFIIE, alpha subunit. (450 aa)
	PEX2_075550	Uncharacterized protein. (294 aa)
	PEX2_016890	TFIID subunit, WD40-associated region. (751 aa)
	PEX2_107870	Peptidase S8/S53, subtilisin/kexin/sedolisin. (901 aa)
	PEX2_027080	Acyltransferase 3. (457 aa)
	PEX2_056450	NAD(P)-bd_dom domain-containing protein. (320 aa)
	PEX2_108970	Uncharacterized protein. (179 aa)
	PEX2_087860	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
	PEX2_084720	Nucleic acid-binding, OB-fold. (2229 aa)
	PEX2_021610	Mitotic checkpoint protein PRCC, C-terminal. (399 aa)
	PEX2_035620	Transcription factor TFIIB. (350 aa)
	PEX2_063340	Uncharacterized protein. (683 aa)
	PEX2_032730	Transcription initiation factor IIA, gamma subunit. (496 aa)
	PEX2_046590	Acyltransferase 3. (481 aa)
	PEX2_005540	Transcription factor IIA, alpha/beta subunit. (372 aa)
	PEX2_013930	Uncharacterized protein. (258 aa)
	PEX2_068040	BRO1 domain-containing protein. (562 aa)
	PEX2_040560	Uncharacterized protein. (837 aa)
	PEX2_086780	Eukaryotic rRNA processing. (359 aa)
	PEX2_067980	TAFII55 protein, conserved region. (474 aa)
	PEX2_000550	Helicase, C-terminal. (822 aa)
	PEX2_103900	Uncharacterized protein. (642 aa)
	PEX2_023490	Chromatin modification-related protein. (416 aa)
	PEX2_028400	TATA-box binding protein. (262 aa)
	PEX2_006940	Transcription factor, fungi. (772 aa)
	PEX2_056210	Actin-binding FH2. (641 aa)
	PEX2_027890	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (293 aa)
	PEX2_031940	Uncharacterized protein. (497 aa)
	PEX2_090870	Uncharacterized protein. (160 aa)
	PEX2_031820	Epimerase domain-containing protein. (287 aa)
	PEX2_108960	Uncharacterized protein. (308 aa)
	PEX2_028420	Nucleotide-binding, alpha-beta plait. (321 aa)
	PEX2_098160	Acyltransferase 3. (473 aa)
	PEX2_098130	TATA box binding protein associated factor (TAF). (442 aa)
	PEX2_019640	Histone-fold. (616 aa)
	PEX2_007590	Transcription factor, fungi. (502 aa)
	PEX2_083260	Uncharacterized protein. (234 aa)
	PEX2_066550	Transcription initiation factor IIF, beta subunit. (363 aa)
	PEX2_033900	Ssl1 domain-containing protein. (232 aa)
	PEX2_067990	Bromodomain transcription factor. (215 aa)
	PEX2_040100	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	PEX2_038130	Uncharacterized protein. (1243 aa)
	PEX2_098150	Histone-fold. (397 aa)
	PEX2_003980	DUF3591 domain-containing protein. (1116 aa)
	PEX2_077350	Chromatin modification-related protein. (678 aa)
	PEX2_075630	Histone-fold. (389 aa)
	PEX2_035240	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (479 aa)
	PEX2_087740	Transcription factor Tfb4. (379 aa)
	PEX2_005710	Histone-fold. (293 aa)
	PEX2_090690	High mobility group, superfamily. (301 aa)
	PEX2_022850	Zn(2)-C6 fungal-type domain-containing protein. (896 aa)
	PEX2_060920	Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal. (1481 aa)
	PEX2_028550	DUF4211 domain-containing protein. (654 aa)
	PEX2_103920	Chromatin modification-related protein. (617 aa)

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PEX2_000550	PEX2_003980	A0A0A2JYV8	A0A0A2JNS8	Helicase, C-terminal.	DUF3591 domain-containing protein.	0.864
PEX2_000550	PEX2_005540	A0A0A2JYV8	A0A0A2K4R1	Helicase, C-terminal.	Transcription factor IIA, alpha/beta subunit.	0.975
PEX2_000550	PEX2_005710	A0A0A2JYV8	A0A0A2JKE0	Helicase, C-terminal.	Histone-fold.	0.864
PEX2_000550	PEX2_007180	A0A0A2JYV8	A0A0A2I749	Helicase, C-terminal.	Cdk-activating kinase assembly factor MAT1, centre.	0.996
PEX2_000550	PEX2_012230	A0A0A2JYV8	A0A0A2I779	Helicase, C-terminal.	Helicase-like, DEXD box c2 type.	0.999
PEX2_000550	PEX2_016890	A0A0A2JYV8	A0A0A2IDX5	Helicase, C-terminal.	TFIID subunit, WD40-associated region.	0.864
PEX2_000550	PEX2_019640	A0A0A2JYV8	A0A0A2I4D0	Helicase, C-terminal.	Histone-fold.	0.875
PEX2_000550	PEX2_027080	A0A0A2JYV8	A0A0A2IHR8	Helicase, C-terminal.	Acyltransferase 3.	0.838
PEX2_000550	PEX2_027890	A0A0A2JYV8	A0A0A2J4H9	Helicase, C-terminal.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.996
PEX2_000550	PEX2_028400	A0A0A2JYV8	A0A0A2JD85	Helicase, C-terminal.	TATA-box binding protein.	0.981
PEX2_000550	PEX2_028550	A0A0A2JYV8	A0A0A2JD98	Helicase, C-terminal.	DUF4211 domain-containing protein.	0.843
PEX2_000550	PEX2_032730	A0A0A2JYV8	A0A0A2KAL5	Helicase, C-terminal.	Transcription initiation factor IIA, gamma subunit.	0.969
PEX2_000550	PEX2_033900	A0A0A2JYV8	A0A0A2I0G9	Helicase, C-terminal.	Ssl1 domain-containing protein.	0.999
PEX2_000550	PEX2_035240	A0A0A2JYV8	A0A0A2JLB3	Helicase, C-terminal.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
PEX2_000550	PEX2_035620	A0A0A2JYV8	A0A0A2KN76	Helicase, C-terminal.	Transcription factor TFIIB.	0.986
PEX2_000550	PEX2_038130	A0A0A2JYV8	A0A0A2JPZ1	Helicase, C-terminal.	Uncharacterized protein.	0.880
PEX2_000550	PEX2_040100	A0A0A2JYV8	A0A0A2JR15	Helicase, C-terminal.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.983
PEX2_000550	PEX2_040560	A0A0A2JYV8	A0A0A2K0D7	Helicase, C-terminal.	Uncharacterized protein.	0.952
PEX2_000550	PEX2_046370	A0A0A2JYV8	A0A0A2I951	Helicase, C-terminal.	Transcription factor TFIIE, alpha subunit.	0.996
PEX2_000550	PEX2_046590	A0A0A2JYV8	A0A0A2K6Z8	Helicase, C-terminal.	Acyltransferase 3.	0.838