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| | CDG11592.1 | Predicted diguanylate cyclase. (570 aa) |
| | citG | triphosphoribosyl-dephospho-CoA transferase. (294 aa) |
| | citX | Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. (182 aa) |
| | dgkA_2 | Putative diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (121 aa) |
| | sgbK | Putative L-xylulose/3-keto-L-gulonate kinase 1; Belongs to the FGGY kinase family. (495 aa) |
| | CDG13118.1 | Putative signaling protein. (366 aa) |
| | fruA | Fused fructose-specific PTS enzymes: IIBcomponent /IIC component. (561 aa) |
| | fruK | Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (313 aa) |
| | rbsK-2 | Putative carbohydrate kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (308 aa) |
| | lpxT | Undecaprenyl pyrophosphate phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (236 aa) |
| | ttrS | Two-component system sensor kinase for tetrathionate reductase complex. (587 aa) |
| | rcsD | Phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (900 aa) |
| | rcsC | Hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (953 aa) |
| | ackA | Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | CDG13285.1 | Putative PTS system, IIC component. (459 aa) |
| | CDG13286.1 | PTS system, IIB component. (93 aa) |
| | tctE | Two-component system sensor kinase. (472 aa) |
| | CDG13375.1 | Two-component system sensor kinase. (569 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (320 aa) |
| | CDG13405.1 | Hypothetical protein. (71 aa) |
| | ptsI | PEP-protein phosphotransferase of PTS systemenzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa) |
| | crr | Glucose-specific enzyme IIA component of PTS. (169 aa) |
| | CDG13413.1 | Two-component system sensor kinase. (441 aa) |
| | CDG13434.1 | Toxin-antitoxin system, toxin component. (118 aa) |
| | CDG13444.1 | Putative glycerone kinase. (218 aa) |
| | dhaK | PTS-dependent dihydroxyacetone kinase. (333 aa) |
| | narQ | Nitrate/nitrite sensor protein NarQ. (558 aa) |
| | ppk | Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (687 aa) |
| | CDG13503.1 | Putative signal transduction protein. (1109 aa) |
| | baeS | Two-component system sensor kinase. (460 aa) |
| | CDG13520.1 | Putative kinase; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. (301 aa) |
| | srlE | Glucitol/sorbitol-specific enzyme IIB component of PTS. (326 aa) |
| | srlB | Glucitol/sorbitol-specific enzyme IIA component of PTS. (120 aa) |
| | thiD | Bifunctional hydroxy-methylpyrimidinekinase/hydroxy- phosphomethylpyrimidine kinase. (266 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (263 aa) |
| | CDG13550.1 | Bifunctional protein, two-component sensorkinase and response regulator. (593 aa) |
| | ndk | Multifunctional nucleoside diphosphatekinaseand apyrimidinic endonuclease and3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
| | glrK | Two-component system sensor kinase. (478 aa) |
| | CDG13612.1 | PTS system, EIIBC component. (455 aa) |
| | CDG13615.1 | Putative sulfatase. (516 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase 1; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa) |
| | ppnK | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa) |
| | CDG13686.1 | Two-component system sensor kinase. (530 aa) |
| | pssA | Phosphatidylserine synthase. (452 aa) |
| | dnaE | DNA polymerase III, alpha subunit. (1162 aa) |
| | cdsA | CDP-diglyceride synthase; Belongs to the CDS family. (280 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | glnD | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (887 aa) |
| | ptsP | Fused phosphoenolpyruvate-proteinphosphotransferase PtsP/GAF domain; Belongs to the PEP-utilizing enzyme family. (748 aa) |
| | agaF | Putative N-acetylgalactosamine-specific PTS system, IIA component. (144 aa) |
| | agaV | N-acetylgalactosamine-specific enzyme IIB component of PTS. (158 aa) |
| | agaZ | Putative tagatose 6-phosphate kinase. (427 aa) |
| | creC | Two-component system sensor kinase. (472 aa) |
| | CDG15310.1 | Putative signal transduction protein. (415 aa) |
| | nadR | Bifunctional DNA-binding transcriptional repressor /NMN adenylyltransferase. (424 aa) |
| | holD | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (145 aa) |
| | CDG15283.1 | Putative signal transduction protein. (359 aa) |
| | rmlA2_1 | Glucose-1-phosphate thymidylyltransferase 1; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | ascF | Fused cellobiose/arbutin/salicin-specific PTSenzymes: IIB component/IC component. (468 aa) |
| | holC | DNA polymerase III, chi subunit. (149 aa) |
| | treB | Trehalose-specific PTS system, EIIBC component. (471 aa) |
| | phnN | ATP-binding protein; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (189 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (705 aa) |
| | pmrB | Two-component system sensor kinase. (353 aa) |
| | entE | Enterobactin synthase subunit E. (542 aa) |
| | CDG14939.1 | Two-component system sensor kinase. (424 aa) |
| | rpoC | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa) |
| | rpoB | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa) |
| | coaA | Pantothenate kinase. (316 aa) |
| | ubiB | Ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (543 aa) |
| | rffH | Glucose-1-phosphate thymidylyltransferase 1; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | umuC | UmuC protein. (438 aa) |
| | wzzE | Enterobacterial common antigen polysaccharidechain length modulation protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (351 aa) |
| | wecA | undecaprenyl-phosphatealpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (380 aa) |
| | uhpB | Two-component system sensor kinase. (514 aa) |
| | eptB | Phosphoethanolamine transferase. (564 aa) |
| | bglF | Beta-glucoside-specific PTS system, EIIABC components. (620 aa) |
| | CDG14786.1 | Putative nucleotidyltransferase. (247 aa) |
| | CDG14778.1 | Two-component system sensor kinase. (391 aa) |
| | mtlA | Fused mannitol-specific PTS enzymes:IIAcomponents /IIB components/IIC components. (639 aa) |
| | CDG14731.1 | Putative carbohydrate kinase. (321 aa) |
| | dnaN | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa) |
| | CDG14705.1 | Hypothetical protein; Belongs to the P-Pant transferase superfamily. (241 aa) |
| | glmU | Fused N-acetylglucosamine-1- phosphateuridyltransferase/glucosamine-1-phosphate acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (457 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (308 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (195 aa) |
| | rdoA | Putative phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (932 aa) |
| | glnL | Nitrogen regulation protein NR(II). (349 aa) |
| | spoT | Bifunctional (p)ppGpp synthetaseII/guanosine-3',5'-bis pyrophosphate3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (703 aa) |
| | rpoZ | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | yicC | Hypothetical protein. (287 aa) |
| | rph | Defective ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | cpxA | Two-component system sensor kinase. (464 aa) |
| | pfkA | 6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (502 aa) |
| | metL | Bifunctional aspartokinase/homoserinedehydrogenase II; In the C-terminal section; belongs to the homoserine dehydrogenase family. (811 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa) |
| | kdgK | 2-dehydro-3-deoxygluconokinase. (310 aa) |
| | CDG14518.1 | Bifunctional regulatory protein,two-componentsystem sensor kinase and response regulator. (594 aa) |
| | CDG14505.1 | Putative carbohydrate kinase. (545 aa) |
| | iolC | Putative myo-inositol catabolism carbohydratekinase. (643 aa) |
| | idnK | Thermoresistant gluconokinase 1. (175 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (425 aa) |
| | envZ | Sensory histidine kinase in two-component regulatory system with OmpR. (456 aa) |
| | aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | CDG14395.1 | Two-component system sensor kinase. (561 aa) |
| | prkB | Probable phosphoribulokinase. (289 aa) |
| | slyX | Hypothetical protein; Belongs to the SlyX family. (75 aa) |
| | rpoA | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa) |
| | rimN | Putative dsRNA-binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (189 aa) |
| | aceK | Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (595 aa) |
| | gntK | Gluconate kinase 2. (179 aa) |
| | lysC | Aspartokinase III; Belongs to the aspartokinase family. (455 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa) |
| | rnk | Regulator of nucleoside diphosphate kinase; May act as an anti-Gre factor; Belongs to the Rnk family. (136 aa) |
| | CDG14172.1 | Putative BglB-family transcriptional antiterminator. (654 aa) |
| | npr | Phosphohistidinoprotein-hexosephosphotransferase component of N-regulated PTS system. (90 aa) |
| | ptsN | Sugar-specific enzyme IIA component of PTS. (153 aa) |
| | rpoN | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa) |
| | arcB | Hybrid sensory histidine kinase in two-component regulatory system with ArcA. (779 aa) |
| | CDG14102.1 | Putative phosphatidylethanolamine-binding protein. (213 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (582 aa) |
| | cca | Multifunctional tRNAnucleotidyltransferase/2'3'- cyclicphosphodiesterase/2'nucleotidase/phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular [...] (414 aa) |
| | glnE | Fused deadenylyltransferase/adenylyltransferasefor glutamine synthetase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of G [...] (945 aa) |
| | rfaE | Fused heptose 7-phosphatekinase/heptose1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (476 aa) |
| | dhaK-2 | PTS-dependent dihydroxyacetone kinase,dihydroxyacetone-binding subunit. (368 aa) |
| | dhaL | PTS-dependent dihydroxyacetone kinase,ADP-binding subunit. (210 aa) |
| | dhaM | PTS-dependent dihydroxyacetone kinase,phosphotransferase subunit; Belongs to the PEP-utilizing enzyme family. (476 aa) |
| | CDG14056.1 | Putative carbohydrate kinase. (310 aa) |
| | scrA | Sucrose-specific PTS system, EIIBC component. (456 aa) |
| | scrK | Fructokinase; Belongs to the carbohydrate kinase PfkB family. (307 aa) |
| | CDG13990.1 | Hypothetical protein. (194 aa) |
| | qseC | Two-component system sensor kinase. (452 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. (166 aa) |
| | pcnB | poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (438 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | CDG13897.1 | L-xylulose/3-keto-L-gulonate kinase. (496 aa) |
| | rssA | Swarming motility regulation two-componentsystem,sensor kinase; Member of the two-component regulatory system RssA/RssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/RssB regulates cellular fatty acid composition, hemolysin production and cell surface topography. RssA/RssB negatively regulates the activity of SlhBA. It can also act as a negative regulator for the control of the swarming initiation. (468 aa) |
| | CDG13855.1 | Putative sugar kinase. (301 aa) |
| | thrA | Fused aspartokinase I and homoserinedehydrogenase I; In the N-terminal section; belongs to the aspartokinase family. (819 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | mog | Predicted molybdochelatase. (195 aa) |
| | ribF | Bifunctional riboflavin kinase/FAD synthetase; Belongs to the ribF family. (312 aa) |
| | polB | DNA polymerase II. (788 aa) |
| | mraY | phospho-N-acetylmuramoyl- pentapeptidetransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa) |
| | barA | Hybrid sensory histidine kinase in two-component regulatory system with UvrY. (908 aa) |
| | relA | (p)ppGpp synthetase I/GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (743 aa) |
| | cysD | Sulfate adenylyltransferase, subunit 2. (302 aa) |
| | cysN | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | cysC | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (208 aa) |
| | ispD | 4-diphosphocytidyl-2C-methyl-D- erythritolsynthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (235 aa) |
| | chbB | N,N'-diacetylchitobiose-specific enzyme IIB component of PTS. (105 aa) |
| | chbC | N,N'-diacetylchitobiose-specific enzyme IIC component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (453 aa) |
| | dnaQ | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (247 aa) |
| | mtnK | Putative methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (399 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (353 aa) |
| | proB | Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | aroL | Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (174 aa) |
| | mak | Fructokinase. (304 aa) |
| | phoR | Phosphate regulon sensor protein PhoR. (438 aa) |
| | thiL | Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (330 aa) |
| | thiI | Sulfurtransferase required for thiamine and4-thiouridine biosynthesis; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa) |
| | dnaX | DNA polymerase III/DNA elongation factor III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (652 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | CDG10976.1 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. (387 aa) |
| | gsk | Inosine/guanosine kinase. (434 aa) |
| | CDG11009.1 | Putative signaling protein. (482 aa) |
| | adrA | Putative signaling protein. (355 aa) |
| | nadD | Nicotinic acid mononucleotideadenylyltransferase,NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa) |
| | holA | DNA polymerase III, delta subunit. (344 aa) |
| | nagE | Fused N-acetyl glucosamine specific PTS enzyme:IIC, IIB, and IIA components. (678 aa) |
| | kdpD | Fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein. (898 aa) |
| | CDG11113.1 | Bifunctional two-component sensor kinase andresponse regulator. (1066 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (383 aa) |
| | galT | Galactose-1-phosphate uridylyltransferase. (350 aa) |
| | ybhB_2 | Putative phosphatidylethanolamine-binding protein. (160 aa) |
| | CDG11151.1 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (305 aa) |
| | CDG11167.1 | Two-component response regulator. (513 aa) |
| | lsrK | Autoinducer-2 kinase LsrK; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (521 aa) |
| | CDG11236.1 | Putative protein kinase. (282 aa) |
| | CDG11262.1 | Putative ABC transporter, substrate-binding protein. (422 aa) |
| | CDG11339.1 | Hypothetical protein. (184 aa) |
| | CDG11349.1 | Hypothetical protein. (419 aa) |
| | CDG11356.1 | Two-component sensor kinase; Member of a two-component regulatory system. (472 aa) |
| | CDG11357.1 | Two-component sensor kinase. (488 aa) |
| | udk | Uridine/cytidine kinase. (213 aa) |
| | CDG11429.1 | Glucose-1-phosphate uridylyltransferase. (300 aa) |
| | CDG11430.1 | Predicted subunit with GalU. (297 aa) |
| | wzc | Tyrosine kinase. (724 aa) |
| | CDG11447.1 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (474 aa) |
| | manC2 | Mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (470 aa) |
| | CDG11532.1 | PTS system, EIIBC component. (518 aa) |
| | cmk | Cytidylate kinase. (229 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (326 aa) |
| | ycaR | Hypothetical protein; Belongs to the UPF0434 family. (60 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa) |
| | uspG | Universal stress protein. (142 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate3- phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | holB | DNA polymerase III, delta prime subunit. (335 aa) |
| | ptsG | Fused glucose-specific PTS enzymes: IIBcomponent. (477 aa) |
| | thiK | Putative thiamin kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (288 aa) |
| | holE | DNA polymerase III, theta subunit. (76 aa) |
| | dcuS | Sensory histidine kinase in two-component regulatory system with DcuR, regulator of anaerobic fumarate respiration. (537 aa) |
| | prsA | Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methylerythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (288 aa) |
| | CDG11845.1 | Putative transcriptional regulator. (269 aa) |
| | CDG11849.1 | Putative signaling protein. (366 aa) |
| | nagK | N-acetyl-D-glucosamine kinase; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (305 aa) |
| | CDG11861.1 | PTS system, EIIBC component. (519 aa) |
| | phoQ | Sensory histidine kinase in two-component regulatory system with PhoP. (485 aa) |
| | CDG11975.1 | Putative phosphotransferase; Belongs to the fructosamine kinase family. (289 aa) |
| | arnC | Undecaprenyl phosphate-L-Ara4FN transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (326 aa) |
| | lplA | Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. (337 aa) |
| | selO | Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (480 aa) |
| | CDG12021.1 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (273 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa) |
| | pykF | Pyruvate kinase I; Belongs to the pyruvate kinase family. (470 aa) |
| | CDG12052.1 | Putative sulfatase. (545 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (373 aa) |
| | pdxY | Pyridoxal kinase 2/pyridoxine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (286 aa) |
| | str | Streptomycin 3''-kinase. (284 aa) |
| | CDG12091.1 | Putative membrane protein. (146 aa) |
| | malX | Maltose-specific PTS system, EIIBC component. (539 aa) |
| | CDG12147.1 | Putative bacteriocin biosynthesis protein. (508 aa) |
| | CDG12245.1 | Putative signal transduction protein. (706 aa) |
| | CDG12266.1 | Putative signaling protein. (626 aa) |
| | CDG12278.1 | Putative phospholipase. (511 aa) |
| | CDG12290.1 | Hypothetical protein. (99 aa) |
| | CDG12342.1 | Putative signal transduction protein. (480 aa) |
| | CDG12380.1 | Hypothetical protein. (275 aa) |
| | CDG12387.1 | Putative pyridoxine kinase; Belongs to the pyridoxine kinase family. (280 aa) |
| | CDG12398.1 | ROK-family protein. (301 aa) |
| | rstB | Two-component sensor kinase. (434 aa) |
| | pspC | DNA-binding transcriptional activator. (119 aa) |
| | CDG12484.1 | Putative carbohydrate kinase; Belongs to the FGGY kinase family. (507 aa) |
| | xylB | Xylulose kinase. (505 aa) |
| | cls | Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa) |
| | tdk | Thymidine kinase/deoxyuridine kinase. (194 aa) |
| | galU | Glucose-1-phosphate uridylyltransferase. (305 aa) |
| | selD | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (347 aa) |
| | CDG12577.1 | Hypothetical protein. (644 aa) |
| | pykA | Pyruvate kinase II; Belongs to the pyruvate kinase family. (480 aa) |
| | CDG12646.1 | Hypothetical protein. (546 aa) |
| | manX | Fused mannose-specific PTS enzymes:IIAcomponent. (319 aa) |
| | CDG12725.1 | Tyrosine-protein kinase. (727 aa) |
| | wecA-2 | Putative undecaprenyl-phosphatealpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (349 aa) |
| | narX | Nitrate/nitrite sensor protein NarX. (594 aa) |
| | fliA | Flagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (240 aa) |
| | cheY | Chemotaxis regulator transmitting signal to flagellar motor component. (129 aa) |
| | cheA | Chemotaxis protein CheA; Fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY:sensory histidine kinase/signal sensing protein. (672 aa) |
| | CDG12850.1 | Type VI secretion system, serine/threonine protein kinase. (481 aa) |
| | CDG12917.1 | Putative signaling protein. (517 aa) |
| | glgS | Hypothetical protein; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. (70 aa) |
| | mdoB | Phosphoglycerol transferase I. (767 aa) |
| | pswP | Putative 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (211 aa) |
