(6 nodes) One-carbon metabolic process network (Synergistes jonesii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fhs	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (557 aa)
	folD	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
	EH55_10845	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
	EH55_10860	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	EH55_13370	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
	EH55_13375	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)

Your Current Organism:

Synergistes jonesii

NCBI taxonomy Id: 2754
Other names: ATCC 49833, S. jonesii, strain 78-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EH55_10845	EH55_10860	EH55_10845	EH55_10860	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
EH55_10845	EH55_13370	EH55_10845	EH55_13370	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
EH55_10845	EH55_13375	EH55_10845	EH55_13375	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.649
EH55_10845	fhs	EH55_10845	EH55_03910	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family.	0.854
EH55_10845	folD	EH55_10845	EH55_10170	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.922
EH55_10860	EH55_10845	EH55_10860	EH55_10845	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
EH55_10860	EH55_13370	EH55_10860	EH55_13370	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.573
EH55_10860	EH55_13375	EH55_10860	EH55_13375	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
EH55_10860	fhs	EH55_10860	EH55_03910	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family.	0.834
EH55_10860	folD	EH55_10860	EH55_10170	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.833
EH55_13370	EH55_10845	EH55_13370	EH55_10845	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
EH55_13370	EH55_10860	EH55_13370	EH55_10860	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.573
EH55_13370	EH55_13375	EH55_13370	EH55_13375	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
EH55_13370	fhs	EH55_13370	EH55_03910	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family.	0.550
EH55_13370	folD	EH55_13370	EH55_10170	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.547
EH55_13375	EH55_10845	EH55_13375	EH55_10845	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.649
EH55_13375	EH55_10860	EH55_13375	EH55_10860	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
EH55_13375	EH55_13370	EH55_13375	EH55_13370	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
EH55_13375	fhs	EH55_13375	EH55_03910	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family.	0.605
EH55_13375	folD	EH55_13375	EH55_10170	Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.605