STRINGSTRING
EH55_08165 EH55_08165 thyX thyX EH55_11145 EH55_11145 EH55_10860 EH55_10860 EH55_10845 EH55_10845 folD folD fmt fmt purH purH tgt tgt fhs fhs EH55_02685 EH55_02685 EH55_02045 EH55_02045 EH55_12760 EH55_12760 EH55_11480 EH55_11480 EH55_13165 EH55_13165 EH55_13370 EH55_13370 EH55_13375 EH55_13375 EH55_12755 EH55_12755
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EH55_08165Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
thyXThymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (228 aa)
EH55_11145Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (267 aa)
EH55_10860Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
EH55_10845Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
fmtHypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (310 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (374 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (557 aa)
EH55_02685Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
EH55_02045Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
EH55_12760Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
EH55_11480Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
EH55_13165Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
EH55_13370Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
EH55_13375Formiminotransferase-cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
EH55_127555,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (289 aa)
Your Current Organism:
Synergistes jonesii
NCBI taxonomy Id: 2754
Other names: ATCC 49833, S. jonesii, strain 78-1
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.