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rsmE rsmE prmA prmA yqxC yqxC trmK trmK rlmB rlmB ODJ56904.1 ODJ56904.1 yqeM yqeM ODJ57597.1 ODJ57597.1 glyA glyA prmC prmC argF argF BFR44_09510 BFR44_09510 ODJ58323.1 ODJ58323.1 gcvH gcvH ODJ58232.1 ODJ58232.1 ODJ58212.1 ODJ58212.1 ODJ59822.1 ODJ59822.1 ODJ58780.1 ODJ58780.1 ODJ58938.1 ODJ58938.1 metE metE rlmI rlmI ODJ58128.1 ODJ58128.1 purH purH purN purN accA accA trmB trmB ODJ59898.1 ODJ59898.1 ODJ60223.1 ODJ60223.1 rsmI rsmI rlmH rlmH ODJ58615.1 ODJ58615.1 ODJ58614.1 ODJ58614.1 rsmG rsmG accD accD ODJ58540.1 ODJ58540.1 trmD trmD ODJ60266.1 ODJ60266.1 fmt fmt pyrB pyrB ODJ60318.1 ODJ60318.1 thyA thyA ODJ60449.1 ODJ60449.1 rsmA rsmA trmL trmL rlmBB rlmBB rsmD rsmD rsmH rsmH gcvT gcvT menG menG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rsmE16S rRNA (uracil(1498)-N(3))-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (248 aa)
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (313 aa)
yqxCRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
trmKSAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
rlmB23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (247 aa)
ODJ56904.116S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
yqeMSAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
ODJ57597.123S rRNA (uracil-5-)-methyltransferase RumA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (457 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
prmCprotein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (280 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (327 aa)
BFR44_09510Sodium:proton antiporter; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
ODJ58323.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
gcvHGlycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (126 aa)
ODJ58232.1Type I restriction-modification system subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
ODJ58212.123S rRNA (uracil-5-)-methyltransferase RumA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (460 aa)
ODJ59822.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
ODJ58780.1Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
ODJ58938.1Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (761 aa)
rlmI50S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ODJ58128.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (195 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
trmBtRNA (guanosine(46)-N7)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (212 aa)
ODJ59898.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (213 aa)
ODJ60223.1Type I restriction-modification system subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
rsmI16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (299 aa)
rlmH23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)
ODJ58615.1methylphosphotriester-DNA alkyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
ODJ58614.16-O-methylguanine DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
rsmG16S rRNA (guanine(527)-N(7))-methyltransferase; Specifically methylates the N7 position of guanine in position 535 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (238 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa)
ODJ58540.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
trmDtRNA (guanosine(37)-N1)-methyltransferase TrmD; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (249 aa)
ODJ60266.116S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (445 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (314 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (297 aa)
ODJ60318.1rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (319 aa)
ODJ60449.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily. (384 aa)
rsmA16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (297 aa)
trmLtRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (171 aa)
rlmBBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (260 aa)
rsmD16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
rsmH16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (363 aa)
menGBifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (241 aa)
Your Current Organism:
Brochothrix thermosphacta
NCBI taxonomy Id: 2756
Other names: ATCC 11509, B. thermosphacta, CCUG 35132, CIP 103251, DSM 20171, IFO 12167, JCM 20628, LMG 17208, LMG:17208, Microbacterium thermosphactum, NBRC 12167, NCIB 10018, NCIB:10018, NCTC 10822
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