(62 nodes) Mixed, incl. Transmembrane receptor protein tyrosine kinase signaling pathway, and Other semaphorin interactions network (Danaus plexippus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KGM_206145	Putative GRB2-associated-binding protein. (510 aa)
	KGM_203864	Ephrin; Belongs to the ephrin family. (260 aa)
	KGM_210909	Spire. (290 aa)
	KGM_214266	Plexin B. (730 aa)
	KGM_215776	Tyrosine-protein kinase receptor. (1346 aa)
	KGM_216011A	Semaphorin 2a. (454 aa)
	KGM_216011B	Semaphorin 2a. (197 aa)
	KGM_207465	Tyrosine-protein kinase. (718 aa)
	KGM_205098	Syndecan binding protein. (294 aa)
	KGM_205303	Uncharacterized protein. (546 aa)
	KGM_203407	Tyrosine-protein phosphatase non-receptor type 6. (532 aa)
	KGM_203319	Eph receptor. (306 aa)
	KGM_215242	Putative insulin receptor substrate-1. (288 aa)
	KGM_206619	Putative semaphorin 2a; Belongs to the semaphorin family. (665 aa)
	KGM_215834	Uncharacterized protein. (1138 aa)
	KGM_203791	Fasciclin IV; Belongs to the semaphorin family. (860 aa)
	KGM_211905	Tyrosine-protein phosphatase corkscrew. (544 aa)
	KGM_208182	Putative piggyBac transposase Uribo1. (140 aa)
	KGM_215963	Tyrosine-protein phosphatase 10D. (1600 aa)
	KGM_211781	Tyrosine-protein kinase Src42A isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (323 aa)
	KGM_211051	Guanylate cyclase. (1108 aa)
	KGM_211050	Guanylate cyclase. (1238 aa)
	KGM_211780	Tyrosine-protein kinase Src42A. (658 aa)
	KGM_205162	Putative sprouty. (79 aa)
	KGM_200171	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family. (209 aa)
	KGM_210720	Uncharacterized protein. (747 aa)
	KGM_215791	Mitochondrial cardiolipin hydrolase. (195 aa)
	KGM_212764	Signal transduction protein lnk-realted. (475 aa)
	KGM_210076	Uncharacterized protein. (208 aa)
	KGM_208557	Putative fibroblast growth factor receptor substrate 2. (478 aa)
	KGM_204405	Guanine nucleotide-releasing factor 2 like protein. (1350 aa)
	KGM_210910B	Uncharacterized protein. (400 aa)
	KGM_203453	Putative ras GTP exchange factor son of sevenless. (1468 aa)
	KGM_205056	Integrin beta-PS. (122 aa)
	KGM_214362	Tyrosine-protein kinase receptor torso; Belongs to the protein kinase superfamily. Tyr protein kinase family. (566 aa)
	KGM_215410	Uncharacterized protein. (1451 aa)
	KGM_205518B	Leukocyte receptor tyrosine protein kinase. (1526 aa)
	KGM_208778B	Vav isoform 1. (621 aa)
	KGM_203965	Tyrosine phosphatase. (457 aa)
	KGM_207237	Plexin-A4 like protein. (99 aa)
	KGM_210910A	Uncharacterized protein. (364 aa)
	KGM_208777	Vav like protein. (838 aa)
	KGM_211617	Plexin A. (1898 aa)
	KGM_210447	Uncharacterized protein. (552 aa)
	KGM_208886	Dab2-interacting protein. (741 aa)
	KGM_208205	Putative lymphocyte cytosolic protein 2. (550 aa)
	KGM_202429	Putative E3 ubiquitin-protein ligase CBL. (181 aa)
	KGM_201381	Putative Ral guanine nucleotide exchange factor. (577 aa)
	KGM_201775	Insulin receptor. (873 aa)
	KGM_201071	Ras-specific guanine nucleotide-releasing factor 1 like protein. (1444 aa)
	KGM_205344	DRK protein. (211 aa)
	KGM_205518A	Leukocyte receptor tyrosine protein kinase. (957 aa)
	KGM_203215	Uncharacterized protein. (105 aa)
	KGM_212033	Uncharacterized protein. (1008 aa)
	KGM_201490	Shc transforming protein. (411 aa)
	KGM_202868	Tyrosine-protein kinase receptor torso; Belongs to the protein kinase superfamily. Tyr protein kinase family. (634 aa)
	KGM_204510	Plexin-A2. (195 aa)
	KGM_201028	Uncharacterized protein. (173 aa)
	KGM_215992	Vascular endothelial growth factor receptor 2. (1286 aa)
	KGM_206801	Receptor protein-tyrosine kinase. (1446 aa)
	KGM_208227	Tyrosine-protein kinase Fps85D isoform 4. (966 aa)
	KGM_209217	Tyrosine-protein phosphatase non-receptor type 3. (74 aa)

Your Current Organism:

Danaus plexippus

NCBI taxonomy Id: 278856
Other names: D. plexippus plexippus, Danaus plexippus plexippus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGM_200171	KGM_201071	A0A212F0H0	A0A212FI89	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Ras-specific guanine nucleotide-releasing factor 1 like protein.	0.457
KGM_200171	KGM_201381	A0A212F0H0	A0A212FHJ2	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Putative Ral guanine nucleotide exchange factor.	0.457
KGM_200171	KGM_201490	A0A212F0H0	A0A212FK85	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Shc transforming protein.	0.618
KGM_200171	KGM_201775	A0A212F0H0	A0A212FHM5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Insulin receptor.	0.455
KGM_200171	KGM_202429	A0A212F0H0	A0A212FER2	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Putative E3 ubiquitin-protein ligase CBL.	0.638
KGM_200171	KGM_202868	A0A212F0H0	A0A212FKB6	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase receptor torso; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.424
KGM_200171	KGM_203407	A0A212F0H0	A0A212EQI6	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein phosphatase non-receptor type 6.	0.435
KGM_200171	KGM_203453	A0A212F0H0	A0A212F5U9	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Putative ras GTP exchange factor son of sevenless.	0.719
KGM_200171	KGM_203965	A0A212F0H0	A0A212F9N2	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Tyrosine phosphatase.	0.464
KGM_200171	KGM_204405	A0A212F0H0	A0A212F3Y3	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Guanine nucleotide-releasing factor 2 like protein.	0.422
KGM_200171	KGM_205303	A0A212F0H0	A0A212EQ43	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.440
KGM_200171	KGM_205344	A0A212F0H0	A0A212FIT9	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	DRK protein.	0.688
KGM_200171	KGM_205518A	A0A212F0H0	A0A212FJE7	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Leukocyte receptor tyrosine protein kinase.	0.570
KGM_200171	KGM_205518B	A0A212F0H0	A0A212F8R6	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Leukocyte receptor tyrosine protein kinase.	0.570
KGM_200171	KGM_206145	A0A212F0H0	A0A212EGL9	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Putative GRB2-associated-binding protein.	0.588
KGM_200171	KGM_206801	A0A212F0H0	A0A212FMG7	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Receptor protein-tyrosine kinase.	0.749
KGM_200171	KGM_208557	A0A212F0H0	A0A212F3L7	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Putative fibroblast growth factor receptor substrate 2.	0.566
KGM_200171	KGM_210076	A0A212F0H0	A0A212F2X8	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.536
KGM_200171	KGM_211780	A0A212F0H0	A0A212EX88	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase Src42A.	0.417
KGM_200171	KGM_211781	A0A212F0H0	A0A212EX35	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform like protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase Src42A isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.417