(25 nodes) Mixed, incl. JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, and Regulation of defense response to fungus network (Danaus plexippus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KGM_210260A	Pelle; Belongs to the protein kinase superfamily. (364 aa)
	KGM_202662	TRAF6 protein. (480 aa)
	KGM_213169	Mitogen-activated protein kinase. (449 aa)
	KGM_202378	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (357 aa)
	KGM_209923A	Uncharacterized protein. (118 aa)
	KGM_200381	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (409 aa)
	KGM_214646	Uncharacterized protein. (107 aa)
	KGM_208945	Putative serine-threonine protein kinase plant-type. (604 aa)
	KGM_215177	Ubiquitin carboxyl-terminal hydrolase; Belongs to the peptidase C19 family. (354 aa)
	KGM_215176	Ubiquitin carboxyl-terminal hydrolase. (661 aa)
	KGM_205421	OTU domain-containing protein 7B. (585 aa)
	KGM_208786	Mkk7. (682 aa)
	KGM_214645	Uncharacterized protein. (106 aa)
	KGM_200977	TAK1-associated binding protein 2 isoform A. (578 aa)
	KGM_200404	Mitogen-activated protein kinase kinase kinase 7. (159 aa)
	KGM_200403	Mitogen-activated protein kinase kinase kinase 7. (609 aa)
	KGM_208215	Zinc finger Ran-binding domain-containing protein 1. (635 aa)
	KGM_207596	E3 ubiquitin-protein ligase NRDP1. (316 aa)
	KGM_210390	Putative mixed lineage kinase. (228 aa)
	KGM_210392	Putative mixed lineage kinase. (400 aa)
	KGM_210391	Putative mixed lineage kinase. (441 aa)
	KGM_201704	Tak1. (459 aa)
	KGM_214647	Pellino. (330 aa)
	KGM_206835	TRAF-type zinc finger domain-containing protein 1. (502 aa)
	KGM_205936	Putative Myeloid differentiation primary response protein MyD88. (389 aa)

Your Current Organism:

Danaus plexippus

NCBI taxonomy Id: 278856
Other names: D. plexippus plexippus, Danaus plexippus plexippus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGM_200381	KGM_200403	A0A212EZX7	A0A212FDQ9	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 7.	0.993
KGM_200381	KGM_200404	A0A212EZX7	A0A212FDM5	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 7.	0.924
KGM_200381	KGM_200977	A0A212EZX7	A0A212FBJ8	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	TAK1-associated binding protein 2 isoform A.	0.498
KGM_200381	KGM_202662	A0A212EZX7	A0A212ES92	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	TRAF6 protein.	0.681
KGM_200381	KGM_208786	A0A212EZX7	A0A212F8P7	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mkk7.	0.747
KGM_200381	KGM_208945	A0A212EZX7	A0A212F1G3	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Putative serine-threonine protein kinase plant-type.	0.421
KGM_200381	KGM_210390	A0A212EZX7	A0A212FG16	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Putative mixed lineage kinase.	0.598
KGM_200381	KGM_210391	A0A212EZX7	A0A212FG25	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Putative mixed lineage kinase.	0.598
KGM_200381	KGM_210392	A0A212EZX7	A0A212FG20	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Putative mixed lineage kinase.	0.598
KGM_200381	KGM_213169	A0A212EZX7	A0A212EUW4	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.998
KGM_200403	KGM_200381	A0A212FDQ9	A0A212EZX7	Mitogen-activated protein kinase kinase kinase 7.	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.993
KGM_200403	KGM_200977	A0A212FDQ9	A0A212FBJ8	Mitogen-activated protein kinase kinase kinase 7.	TAK1-associated binding protein 2 isoform A.	0.995
KGM_200403	KGM_201704	A0A212FDQ9	A0A212FHC2	Mitogen-activated protein kinase kinase kinase 7.	Tak1.	0.967
KGM_200403	KGM_202378	A0A212FDQ9	A0A212EV13	Mitogen-activated protein kinase kinase kinase 7.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1.	0.604
KGM_200403	KGM_202662	A0A212FDQ9	A0A212ES92	Mitogen-activated protein kinase kinase kinase 7.	TRAF6 protein.	0.996
KGM_200403	KGM_205936	A0A212FDQ9	A0A212FNS6	Mitogen-activated protein kinase kinase kinase 7.	Putative Myeloid differentiation primary response protein MyD88.	0.906
KGM_200403	KGM_208215	A0A212FDQ9	A0A212FEC0	Mitogen-activated protein kinase kinase kinase 7.	Zinc finger Ran-binding domain-containing protein 1.	0.453
KGM_200403	KGM_208786	A0A212FDQ9	A0A212F8P7	Mitogen-activated protein kinase kinase kinase 7.	Mkk7.	0.977
KGM_200403	KGM_213169	A0A212FDQ9	A0A212EUW4	Mitogen-activated protein kinase kinase kinase 7.	Mitogen-activated protein kinase.	0.513
KGM_200404	KGM_200381	A0A212FDM5	A0A212EZX7	Mitogen-activated protein kinase kinase kinase 7.	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.924