(11 nodes) Tumor necrosis factor-mediated signaling pathway network (Danaus plexippus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KGM_202512	ADAM 17 protease. (724 aa)
	KGM_200347	Putative mitogen-activated protein kinase; Belongs to the protein kinase superfamily. (338 aa)
	KGM_203909	Uncharacterized protein. (227 aa)
	KGM_200977	TAK1-associated binding protein 2 isoform A. (578 aa)
	KGM_213331	TRAF3 protein. (501 aa)
	KGM_202662	TRAF6 protein. (480 aa)
	KGM_213169	Mitogen-activated protein kinase. (449 aa)
	KGM_215738	TNFSF13 protein; Belongs to the tumor necrosis factor family. (461 aa)
	KGM_216084	Serine/threonine-protein kinase mig-15. (1359 aa)
	KGM_200381	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (409 aa)
	KGM_208786	Mkk7. (682 aa)

Your Current Organism:

Danaus plexippus

NCBI taxonomy Id: 278856
Other names: D. plexippus plexippus, Danaus plexippus plexippus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGM_200347	KGM_200977	A0A212EP69	A0A212FBJ8	Putative mitogen-activated protein kinase; Belongs to the protein kinase superfamily.	TAK1-associated binding protein 2 isoform A.	0.590
KGM_200347	KGM_202662	A0A212EP69	A0A212ES92	Putative mitogen-activated protein kinase; Belongs to the protein kinase superfamily.	TRAF6 protein.	0.728
KGM_200347	KGM_213169	A0A212EP69	A0A212EUW4	Putative mitogen-activated protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.750
KGM_200381	KGM_200977	A0A212EZX7	A0A212FBJ8	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	TAK1-associated binding protein 2 isoform A.	0.498
KGM_200381	KGM_202662	A0A212EZX7	A0A212ES92	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	TRAF6 protein.	0.681
KGM_200381	KGM_208786	A0A212EZX7	A0A212F8P7	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mkk7.	0.747
KGM_200381	KGM_213169	A0A212EZX7	A0A212EUW4	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.998
KGM_200977	KGM_200347	A0A212FBJ8	A0A212EP69	TAK1-associated binding protein 2 isoform A.	Putative mitogen-activated protein kinase; Belongs to the protein kinase superfamily.	0.590
KGM_200977	KGM_200381	A0A212FBJ8	A0A212EZX7	TAK1-associated binding protein 2 isoform A.	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.498
KGM_200977	KGM_202662	A0A212FBJ8	A0A212ES92	TAK1-associated binding protein 2 isoform A.	TRAF6 protein.	0.998
KGM_200977	KGM_208786	A0A212FBJ8	A0A212F8P7	TAK1-associated binding protein 2 isoform A.	Mkk7.	0.643
KGM_200977	KGM_213331	A0A212FBJ8	A0A212FGT7	TAK1-associated binding protein 2 isoform A.	TRAF3 protein.	0.777
KGM_202662	KGM_200347	A0A212ES92	A0A212EP69	TRAF6 protein.	Putative mitogen-activated protein kinase; Belongs to the protein kinase superfamily.	0.728
KGM_202662	KGM_200381	A0A212ES92	A0A212EZX7	TRAF6 protein.	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.681
KGM_202662	KGM_200977	A0A212ES92	A0A212FBJ8	TRAF6 protein.	TAK1-associated binding protein 2 isoform A.	0.998
KGM_202662	KGM_208786	A0A212ES92	A0A212F8P7	TRAF6 protein.	Mkk7.	0.415
KGM_202662	KGM_213169	A0A212ES92	A0A212EUW4	TRAF6 protein.	Mitogen-activated protein kinase.	0.404
KGM_202662	KGM_213331	A0A212ES92	A0A212FGT7	TRAF6 protein.	TRAF3 protein.	0.973
KGM_202662	KGM_216084	A0A212ES92	A0A212EY98	TRAF6 protein.	Serine/threonine-protein kinase mig-15.	0.912
KGM_203909	KGM_215738	A0A212F9Q4	A0A212EVD9	Uncharacterized protein.	TNFSF13 protein; Belongs to the tumor necrosis factor family.	0.914