(63 nodes) C2 domain superfamily network (Danaus plexippus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KGM_215834	Uncharacterized protein. (1138 aa)
	KGM_214205	E3 ubiquitin-protein ligase. (878 aa)
	KGM_202972	Synaptotagmin-7 like protein. (181 aa)
	KGM_205916	Uncharacterized protein. (1039 aa)
	KGM_204846	Uncharacterized protein. (818 aa)
	KGM_204847	C2 domain-containing protein. (170 aa)
	KGM_213448	Putative pre-mRNA-splicing helicase BRR2. (404 aa)
	KGM_201862	Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (1991 aa)
	KGM_202230	Putative Rpgrip1 like protein. (1300 aa)
	KGM_207160	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1190 aa)
	KGM_205166	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide; Belongs to the PI3/PI4-kinase family. (1747 aa)
	KGM_212588	Phosphoinositide phospholipase C. (959 aa)
	KGM_208825	Uncharacterized protein. (851 aa)
	KGM_201261	Synaptotagmin protein 5. (1977 aa)
	KGM_207805	Active breakpoint cluster region-related protein. (1347 aa)
	KGM_205176	Putative Synaptotagmin-6. (519 aa)
	KGM_200172	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (843 aa)
	KGM_204822	Putative unc-13. (176 aa)
	KGM_204821	Putative unc-13. (58 aa)
	KGM_211535	Multiple C2 and transmembrane domain-containing protein 2. (803 aa)
	KGM_211534	Multiple C2 and transmembrane domain-containing protein 2. (200 aa)
	KGM_216101	Putative Toll-interacting protein. (290 aa)
	KGM_215503	Putative synaptotagmin X. (488 aa)
	KGM_203258	Dedicator of cytokinesis protein 3; Belongs to the DOCK family. (1710 aa)
	KGM_205515	Uncharacterized protein. (837 aa)
	KGM_214256	Dedicator of cytokinesis protein 9; Belongs to the DOCK family. (1678 aa)
	KGM_208658	Multiple C2 and transmembrane domain-containing protein 1. (524 aa)
	KGM_205420	Putative Synaptotagmin-4. (433 aa)
	KGM_214852A	C2 domain-containing protein. (214 aa)
	KGM_214641	Synaptotagmin-14. (587 aa)
	KGM_213788	Kibra isoform 1. (1262 aa)
	KGM_207942	C2 domain-containing protein. (385 aa)
	KGM_203982	Type 1 inositol-3,4-bisphosphate 4-phosphatase isoform 1. (1153 aa)
	KGM_201093	Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
	KGM_201754	FIP-RBD domain-containing protein. (476 aa)
	KGM_203274	Putative rho-gtpase-activating protein. (1280 aa)
	KGM_202973	Synaptotagmin-7 like protein. (293 aa)
	KGM_206976	Uncharacterized protein. (618 aa)
	KGM_206317	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (642 aa)
	KGM_207550	Uncharacterized protein. (1114 aa)
	KGM_205398	Putative coiled-coil domain containing 100. (683 aa)
	KGM_205796	Synaptotagmin I. (428 aa)
	KGM_203241	E3 ubiquitin-protein ligase. (754 aa)
	KGM_213125	Synaptic ras GTPase activating protein. (1783 aa)
	KGM_205379B	Putative pre-mRNA-splicing helicase BRR2. (880 aa)
	KGM_202446	DnaJ-19. (750 aa)
	KGM_208642	C2 domain-containing protein. (132 aa)
	KGM_207251	Multiple C2 and transmembrane domain-containing protein 1. (726 aa)
	KGM_212831	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (752 aa)
	KGM_204827	Uncharacterized protein. (897 aa)
	KGM_204826	Uncharacterized protein. (1873 aa)
	KGM_210366	Putative coiled-coil and C2 domain containing 2A. (1366 aa)
	KGM_214853	C2 domain-containing protein. (1715 aa)
	KGM_203021	Otoferlin. (1687 aa)
	KGM_203020	Otoferlin like protein. (406 aa)
	KGM_203019	Uncharacterized protein. (111 aa)
	KGM_201549A	Uncharacterized protein. (775 aa)
	KGM_206017A	E3 ubiquitin-protein ligase Nedd-4 isoform 1. (275 aa)
	KGM_204224	Putative synaptotagmin. (1014 aa)
	KGM_204270	GTPase-activating protein. (1415 aa)
	KGM_209169	Uncharacterized protein. (1271 aa)
	KGM_201001	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (573 aa)
	KGM_204820	Ras gtpase activating protein. (837 aa)

Your Current Organism:

Danaus plexippus

NCBI taxonomy Id: 278856
Other names: D. plexippus plexippus, Danaus plexippus plexippus

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGM_200172	KGM_201001	A0A212F0E0	A0A212EQA5	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	0.953
KGM_200172	KGM_201093	A0A212F0E0	A0A212F9V4	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.553
KGM_200172	KGM_205166	A0A212F0E0	A0A212EY28	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide; Belongs to the PI3/PI4-kinase family.	0.597
KGM_200172	KGM_207160	A0A212F0E0	A0A212EMM4	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.942
KGM_200172	KGM_212588	A0A212F0E0	A0A212EY45	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphoinositide phospholipase C.	0.904
KGM_200172	KGM_215834	A0A212F0E0	A0A212ET20	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.441
KGM_201001	KGM_200172	A0A212EQA5	A0A212F0E0	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.953
KGM_201001	KGM_201093	A0A212EQA5	A0A212F9V4	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.931
KGM_201001	KGM_205166	A0A212EQA5	A0A212EY28	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide; Belongs to the PI3/PI4-kinase family.	0.930
KGM_201001	KGM_206017A	A0A212EQA5	A0A212ELW9	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	E3 ubiquitin-protein ligase Nedd-4 isoform 1.	0.495
KGM_201001	KGM_207160	A0A212EQA5	A0A212EMM4	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.914
KGM_201001	KGM_207550	A0A212EQA5	A0A212FFD0	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Uncharacterized protein.	0.917
KGM_201001	KGM_212588	A0A212EQA5	A0A212EY45	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Phosphoinositide phospholipase C.	0.900
KGM_201001	KGM_213788	A0A212EQA5	A0A212F9C2	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Kibra isoform 1.	0.473
KGM_201001	KGM_214205	A0A212EQA5	A0A212ETT8	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	E3 ubiquitin-protein ligase.	0.629
KGM_201093	KGM_200172	A0A212F9V4	A0A212F0E0	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.553
KGM_201093	KGM_201001	A0A212F9V4	A0A212EQA5	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	0.931
KGM_201093	KGM_205166	A0A212F9V4	A0A212EY28	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide; Belongs to the PI3/PI4-kinase family.	0.682
KGM_201093	KGM_207160	A0A212F9V4	A0A212EMM4	Phosphatidylinositol 3-kinase catalytic subunit type 3.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.900
KGM_201093	KGM_207550	A0A212F9V4	A0A212FFD0	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Uncharacterized protein.	0.431