STRINGSTRING
dapB dapB aroC aroC nadA nadA aroE aroE Saro_0174 Saro_0174 Saro_0211 Saro_0211 Saro_2567 Saro_2567 lysA lysA Saro_2823 Saro_2823 Saro_3092 Saro_3092 Saro_3175 Saro_3175 Saro_3176 Saro_3176 Saro_3291 Saro_3291 Saro_3304 Saro_3304 Saro_3309 Saro_3309 Saro_0238 Saro_0238 Saro_2515 Saro_2515 Saro_2501 Saro_2501 Saro_2456 Saro_2456 Saro_2337 Saro_2337 Saro_2244 Saro_2244 aroQ aroQ Saro_2045 Saro_2045 Saro_1981 Saro_1981 aroK aroK aroB aroB dapD dapD fumC fumC Saro_1670 Saro_1670 aroE-2 aroE-2 dapA dapA Saro_1433 Saro_1433 asd asd dapF dapF Saro_1352 Saro_1352 aroA aroA Saro_1299 Saro_1299 Saro_1223 Saro_1223 astD astD Saro_0884 Saro_0884 astB astB Saro_0704 Saro_0704 dapE dapE
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (242 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (356 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (332 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa)
Saro_0174succinyl-CoA:(R)-citramalate CoA-transferase; Belongs to the CoA-transferase III family. (400 aa)
Saro_0211Glutamate dehydrogenase (NAD). (1573 aa)
Saro_2567Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (927 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (419 aa)
Saro_2823Amidohydrolase. (422 aa)
Saro_30922-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (167 aa)
Saro_3175Glutamate synthase (NADH) small subunit. (477 aa)
Saro_3176Glutamate synthase (NADH) large subunit. (1546 aa)
Saro_3291Allosteric NADP-dependent malic enzyme. (754 aa)
Saro_3304Aspartate kinase; Belongs to the aspartokinase family. (418 aa)
Saro_3309Peptidase M20. (472 aa)
Saro_0238Peptidase M20. (436 aa)
Saro_2515Amidohydrolase. (426 aa)
Saro_2501L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (390 aa)
Saro_2456L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (408 aa)
Saro_2337Orn/DAP/Arg decarboxylase 2. (408 aa)
Saro_2244Chorismate mutase. (100 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa)
Saro_2045L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (355 aa)
Saro_1981Protein of unknown function DUF339. (93 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (216 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (279 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
Saro_1670Peptidase M20. (467 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (276 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
Saro_1433FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (434 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (275 aa)
Saro_1352Chorismate mutase. (96 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (441 aa)
Saro_1299FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (435 aa)
Saro_1223L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (409 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (471 aa)
Saro_0884Peptidase dimerization. (402 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (421 aa)
Saro_0704L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1147 aa)
dapESuccinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa)
Your Current Organism:
Novosphingobium aromaticivorans
NCBI taxonomy Id: 279238
Other names: N. aromaticivorans DSM 12444, Novosphingobium aromaticivorans DSM 12444, Novosphingobium aromaticivorans str. DSM 12444, Novosphingobium aromaticivorans strain DSM 12444
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