STRINGSTRING
Saro_0010 Saro_0010 Saro_0084 Saro_0084 Saro_0086 Saro_0086 Saro_0091 Saro_0091 Saro_0105 Saro_0105 Saro_0139 Saro_0139 Saro_0144 Saro_0144 Saro_0145 Saro_0145 xseA xseA Saro_0173 Saro_0173 Saro_0174 Saro_0174 Saro_0177 Saro_0177 Saro_0192 Saro_0192 Saro_0211 Saro_0211 Saro_0237 Saro_0237 Saro_0280 Saro_0280 Saro_0385 Saro_0385 Saro_0414 Saro_0414 Saro_0473 Saro_0473 Saro_0505 Saro_0505 Saro_0538 Saro_0538 Saro_0539 Saro_0539 Saro_0554 Saro_0554 Saro_0559 Saro_0559 dut dut Saro_0591 Saro_0591 Saro_0604 Saro_0604 Saro_0673 Saro_0673 Saro_0691 Saro_0691 Saro_0704 Saro_0704 Saro_0707 Saro_0707 Saro_0713 Saro_0713 Saro_0716 Saro_0716 Saro_0776 Saro_0776 Saro_0782 Saro_0782 Saro_0802 Saro_0802 Saro_0840 Saro_0840 Saro_0861 Saro_0861 Saro_0869 Saro_0869 Saro_0871 Saro_0871 astB astB Saro_0883 Saro_0883 astD astD Saro_0941 Saro_0941 Saro_0962 Saro_0962 Saro_1020 Saro_1020 Saro_1054 Saro_1054 Saro_1074 Saro_1074 Saro_1083 Saro_1083 rnhA rnhA Saro_1097 Saro_1097 Saro_1098 Saro_1098 Saro_1099 Saro_1099 Saro_1100 Saro_1100 bpt bpt Saro_1223 Saro_1223 Saro_1233 Saro_1233 Saro_1234 Saro_1234 Saro_1288 Saro_1288 Saro_1292 Saro_1292 gloB gloB Saro_1346 Saro_1346 Saro_1347 Saro_1347 Saro_1434 Saro_1434 Saro_1483 Saro_1483 Saro_1509 Saro_1509 Saro_1546 Saro_1546 Saro_1572 Saro_1572 Saro_1586 Saro_1586 Saro_1637 Saro_1637 Saro_1641 Saro_1641 Saro_1654 Saro_1654 Saro_1680 Saro_1680 Saro_1681 Saro_1681 Saro_1682 Saro_1682 Saro_1701 Saro_1701 Saro_1702 Saro_1702 Saro_1703 Saro_1703 Saro_1798 Saro_1798 Saro_1819 Saro_1819 Saro_1825 Saro_1825 rnhB rnhB Saro_1848 Saro_1848 Saro_1850 Saro_1850 gcvH gcvH gcvPA gcvPA Saro_1853 Saro_1853 edd edd Saro_1933 Saro_1933 Saro_1966 Saro_1966 Saro_2045 Saro_2045 rph rph Saro_2062 Saro_2062 Saro_2092 Saro_2092 Saro_2104 Saro_2104 Saro_2169 Saro_2169 xseB xseB Saro_2266 Saro_2266 Saro_2268 Saro_2268 rne rne Saro_2404 Saro_2404 Saro_2405 Saro_2405 Saro_2422 Saro_2422 Saro_2426 Saro_2426 Saro_2430 Saro_2430 Saro_2431 Saro_2431 Saro_2432 Saro_2432 Saro_2441 Saro_2441 Saro_2443 Saro_2443 Saro_2456 Saro_2456 Saro_2457 Saro_2457 Saro_2461 Saro_2461 Saro_2463 Saro_2463 pnp pnp Saro_2501 Saro_2501 Saro_2515 Saro_2515 Saro_2584 Saro_2584 Saro_2591 Saro_2591 Saro_2598 Saro_2598 Saro_2746 Saro_2746 Saro_2806 Saro_2806 Saro_2809 Saro_2809 Saro_2812 Saro_2812 Saro_2813 Saro_2813 Saro_2814 Saro_2814 Saro_2815 Saro_2815 Saro_2818 Saro_2818 Saro_2819 Saro_2819 Saro_2823 Saro_2823 Saro_2861 Saro_2861 katG katG Saro_2922 Saro_2922 Saro_2939 Saro_2939 Saro_2940 Saro_2940 Saro_2964 Saro_2964 Saro_3037 Saro_3037 Saro_3090 Saro_3090 Saro_3187 Saro_3187 Saro_3281 Saro_3281 Saro_3335 Saro_3335
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Saro_0010Conserved hypothetical protein. (103 aa)
Saro_0084Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (489 aa)
Saro_0086Beta-lactamase-like protein. (311 aa)
Saro_0091NADH:flavin oxidoreductase/NADH oxidase. (367 aa)
Saro_0105Heparinase II/III-like protein. (628 aa)
Saro_0139Carboxymethylenebutenolidase. (232 aa)
Saro_0144Glycoside hydrolase, family 25. (231 aa)
Saro_0145Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (145 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (453 aa)
Saro_0173Isochorismatase hydrolase. (209 aa)
Saro_0174succinyl-CoA:(R)-citramalate CoA-transferase; Belongs to the CoA-transferase III family. (400 aa)
Saro_0177hydroxymethylglutaryl-CoA lyase. (304 aa)
Saro_0192Gamma-glutamyltransferase 1, Threonine peptidase, MEROPS family T03. (583 aa)
Saro_0211Glutamate dehydrogenase (NAD). (1573 aa)
Saro_0237DEAD/DEAH box helicase-like protein. (498 aa)
Saro_0280Beta-lactamase. (353 aa)
Saro_0385Hypothetical protein. (325 aa)
Saro_0414Glutathione-dependent formaldehyde-activating, GFA. (132 aa)
Saro_0473Ppx/GppA phosphatase. (435 aa)
Saro_0505Hypothetical protein. (128 aa)
Saro_0538Benzoate 1,2-dioxygenase, alpha subunit. (444 aa)
Saro_05392-chlorobenzoate 1,2-dioxygenase. (161 aa)
Saro_05543-hydroxyacyl-CoA dehydrogenase. (290 aa)
Saro_05595'-nucleotidase; Belongs to the 5'-nucleotidase family. (583 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (157 aa)
Saro_0591Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (395 aa)
Saro_0604Hypothetical protein. (310 aa)
Saro_0673Fumarylacetoacetate (FAA) hydrolase. (314 aa)
Saro_0691Alpha/beta hydrolase. (290 aa)
Saro_0704L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1147 aa)
Saro_0707Rieske (2Fe-2S) protein. (341 aa)
Saro_0713Glyoxalase/bleomycin resistance protein/dioxygenase. (300 aa)
Saro_0716Putative cyclase. (259 aa)
Saro_0776Oxidoreductase-like protein. (391 aa)
Saro_0782Phytanoyl-CoA dioxygenase. (274 aa)
Saro_0802Carotenoid oxygenase. (494 aa)
Saro_0840Flavin-containing monooxygenase FMO. (507 aa)
Saro_08613-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (289 aa)
Saro_08693-hydroxyacyl-CoA dehydrogenase. (418 aa)
Saro_0871Conserved hypothetical protein. (282 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (421 aa)
Saro_0883Arginine succinyltransferase. (345 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (471 aa)
Saro_0941Alpha/beta hydrolase. (284 aa)
Saro_0962NUDIX hydrolase. (293 aa)
Saro_1020Phytanoyl-CoA dioxygenase. (296 aa)
Saro_1054Amidohydrolase-like protein. (576 aa)
Saro_1074Fumarylacetoacetate (FAA) hydrolase. (335 aa)
Saro_1083FAD dependent oxidoreductase. (369 aa)
rnhARNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (143 aa)
Saro_1097Amidohydrolase. (568 aa)
Saro_10983-hydroxyisobutyrate dehydrogenase. (312 aa)
Saro_1099Hypothetical protein. (136 aa)
Saro_1100L-threonine ammonia-lyase. (421 aa)
bptArginyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. (284 aa)
Saro_1223L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (409 aa)
Saro_1233Protocatechuate 4,5-dioxygenase alpha subunit. (242 aa)
Saro_1234Protocatechuate 4,5-dioxygenase beta subunit. (280 aa)
Saro_1288N-formylglutamate amidohydrolase. (302 aa)
Saro_1292DEAD/DEAH box helicase-like protein; Belongs to the DEAD box helicase family. (464 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (254 aa)
Saro_1346(2Fe-2S)-binding protein. (175 aa)
Saro_1347Twin-arginine translocation pathway signal. (769 aa)
Saro_1434Alpha/beta hydrolase. (261 aa)
Saro_1483Phytanoyl-CoA dioxygenase. (269 aa)
Saro_1509Hypothetical protein. (129 aa)
Saro_1546Taurine dioxygenase. (316 aa)
Saro_1572NADH:flavin oxidoreductase/NADH oxidase. (363 aa)
Saro_15864-hydroxyphenylpyruvate dioxygenase. (621 aa)
Saro_1637DoxX. (137 aa)
Saro_1641MaoC-like dehydratase. (149 aa)
Saro_1654Isoamylase; Belongs to the glycosyl hydrolase 13 family. (588 aa)
Saro_1680Ring hydroxylating dioxygenase, alpha subunit. (447 aa)
Saro_1681Aromatic-ring-hydroxylating dioxygenase, beta subunit. (166 aa)
Saro_1682L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
Saro_1701Protein of unknown function DUF182. (325 aa)
Saro_1702Twin-arginine translocation pathway signal. (720 aa)
Saro_1703(2Fe-2S)-binding protein. (167 aa)
Saro_1798Beta-lactamase-like protein. (306 aa)
Saro_1819Flavin-containing monooxygenase FMO. (505 aa)
Saro_1825Glutathione-dependent formaldehyde-activating, GFA. (135 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (196 aa)
Saro_1848Deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (389 aa)
Saro_1850Aminomethyltransferase. (388 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa)
Saro_1853Glycine dehydrogenase (decarboxylating) beta subunit. (519 aa)
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (606 aa)
Saro_1933MazG family protein. (274 aa)
Saro_1966Conserved hypothetical protein. (156 aa)
Saro_2045L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (355 aa)
rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (227 aa)
Saro_2062Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (209 aa)
Saro_2092Glutathione-dependent formaldehyde-activating, GFA. (147 aa)
Saro_2104Dienelactone hydrolase. (234 aa)
Saro_2169TraG-like protein. (900 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (83 aa)
Saro_2266Epoxide hydrolase-like protein. (377 aa)
Saro_2268Amidohydrolase 2. (348 aa)
rneRNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (935 aa)
Saro_2404Aminomethyltransferase; Belongs to the GcvT family. (462 aa)
Saro_2405Glutathione S-transferase-like protein. (279 aa)
Saro_2422Hypothetical protein. (757 aa)
Saro_24265-carboxymethyl-2-hydroxymuconate delta-isomerase. (281 aa)
Saro_2430Altronate dehydratase. (402 aa)
Saro_2431D-galactarate dehydratase/Altronate hydrolase-like protein. (109 aa)
Saro_2432Amidohydrolase 2. (277 aa)
Saro_2441Glycerol kinase; Belongs to the FGGY kinase family. (487 aa)
Saro_2443Alkanesulfonate monooxygenase. (362 aa)
Saro_2456L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (408 aa)
Saro_2457Beta-lactamase-like protein. (301 aa)
Saro_2461Phosphoesterase, PA-phosphatase related protein. (254 aa)
Saro_2463Fumarylacetoacetate hydrolase. (431 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (772 aa)
Saro_2501L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (390 aa)
Saro_2515Amidohydrolase. (426 aa)
Saro_2584DEAD/DEAH box helicase-like protein; Belongs to the DEAD box helicase family. (590 aa)
Saro_2591Dipeptidyl-peptidase 7, Serine peptidase, MEROPS family S46; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. (714 aa)
Saro_25985-carboxymethyl-2-hydroxymuconate delta-isomerase. (296 aa)
Saro_2746Glycoside hydrolase, family 19. (196 aa)
Saro_2806Dienelactone hydrolase. (287 aa)
Saro_2809Carotenoid oxygenase. (497 aa)
Saro_2812Protocatechuate 4,5-dioxygenase beta subunit. (280 aa)
Saro_2813Protocatechuate 4,5-dioxygenase alpha subunit. (145 aa)
Saro_28144-oxalomesaconate hydratase. (341 aa)
Saro_28156-phosphogluconate dehydrogenase, NAD-binding protein. (277 aa)
Saro_2818Methylitaconate delta2-delta3-isomerase. (352 aa)
Saro_28192-pyrone-4,6-dicarboxylate hydrolase. (296 aa)
Saro_2823Amidohydrolase. (422 aa)
Saro_2861Aminomethyltransferase; Belongs to the GcvT family. (466 aa)
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (747 aa)
Saro_2922Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. (285 aa)
Saro_2939FAD dependent oxidoreductase. (378 aa)
Saro_2940BFD-like (2Fe-2S)-binding protein. (459 aa)
Saro_2964Beta-lactamase-like protein. (292 aa)
Saro_3037Glyoxalase/bleomycin resistance protein/dioxygenase. (145 aa)
Saro_3090Endoribonuclease L-PSP. (128 aa)
Saro_3187Phenylalanine 4-hydroxylase. (312 aa)
Saro_3281(2Fe-2S)-binding protein. (169 aa)
Saro_3335Twin-arginine translocation pathway signal. (766 aa)
Your Current Organism:
Novosphingobium aromaticivorans
NCBI taxonomy Id: 279238
Other names: N. aromaticivorans DSM 12444, Novosphingobium aromaticivorans DSM 12444, Novosphingobium aromaticivorans str. DSM 12444, Novosphingobium aromaticivorans strain DSM 12444
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