STRINGSTRING
Saro_0021 Saro_0021 Saro_0732 Saro_0732 Saro_0733 Saro_0733 Saro_0735 Saro_0735 Saro_0736 Saro_0736 Saro_0874 Saro_0874 Saro_0995 Saro_0995 mdh mdh Saro_1685 Saro_1685 Saro_1688 Saro_1688 Saro_1964 Saro_1964 eno eno glyA glyA Saro_2259 Saro_2259 Saro_2567 Saro_2567 acsA acsA Saro_2679 Saro_2679 Saro_2680 Saro_2680 Saro_2922 Saro_2922 Saro_3028 Saro_3028 gpmA gpmA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Saro_0021Fructose-1,6-bisphosphatase, class II. (330 aa)
Saro_0732Formate dehydrogenase gamma subunit. (137 aa)
Saro_0733Formate dehydrogenase beta subunit. (512 aa)
Saro_0735Formate dehydrogenase alpha subunit. (952 aa)
Saro_0736Hypothetical protein. (88 aa)
Saro_0874Alcohol dehydrogenase superfamily, zinc-containing; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa)
Saro_0995Alcohol dehydrogenase, zinc-containing. (362 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
Saro_1685Amine dehydrogenase. (391 aa)
Saro_1688Amine dehydrogenase; Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin; Belongs to the aromatic amine dehydrogenase light chain family. (186 aa)
Saro_1964Fructose-bisphosphate aldolase. (301 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (436 aa)
Saro_2259Phosphoserine phosphatase. (294 aa)
Saro_2567Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (927 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
Saro_2679Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (379 aa)
Saro_2680D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (540 aa)
Saro_2922Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. (285 aa)
Saro_3028Quinohemoprotein amine dehydrogenase, 60 kDa subunit. (594 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (228 aa)
Your Current Organism:
Novosphingobium aromaticivorans
NCBI taxonomy Id: 279238
Other names: N. aromaticivorans DSM 12444, Novosphingobium aromaticivorans DSM 12444, Novosphingobium aromaticivorans str. DSM 12444, Novosphingobium aromaticivorans strain DSM 12444
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