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Saro_0425 Saro_0425 Saro_0446 Saro_0446 argC argC leuC leuC leuD leuD Saro_1282 Saro_1282 asd asd ilvD ilvD argJ argJ Saro_2032 Saro_2032 Saro_2261 Saro_2261 Saro_2262 Saro_2262 ilvC ilvC leuA leuA Saro_2379 Saro_2379 leuB leuB Saro_2671 Saro_2671 argD argD argB argB Saro_3304 Saro_3304
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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Saro_0425Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (890 aa)
Saro_0446Aminotransferase. (389 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (309 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (478 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa)
Saro_1282Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
ilvDDihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (615 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa)
Saro_2032Citrate synthase; Belongs to the citrate synthase family. (428 aa)
Saro_2261Acetolactate synthase, large subunit. (582 aa)
Saro_2262Acetolactate synthase, small subunit. (172 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (556 aa)
Saro_2379Thiamine pyrophosphate enzyme-like TPP-binding protein; Belongs to the TPP enzyme family. (563 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (369 aa)
Saro_2671Branched chain amino acid aminotransferase apoenzyme. (367 aa)
argDAcetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (397 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (303 aa)
Saro_3304Aspartate kinase; Belongs to the aspartokinase family. (418 aa)
Your Current Organism:
Novosphingobium aromaticivorans
NCBI taxonomy Id: 279238
Other names: N. aromaticivorans DSM 12444, Novosphingobium aromaticivorans DSM 12444, Novosphingobium aromaticivorans str. DSM 12444, Novosphingobium aromaticivorans strain DSM 12444
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