STRINGSTRING
ARJ28603.1 ARJ28603.1 ARJ28788.1 ARJ28788.1 ARJ28828.1 ARJ28828.1 ARJ28829.1 ARJ28829.1 sdaAA sdaAA ARJ28831.1 ARJ28831.1 ARJ28884.1 ARJ28884.1 luxS luxS metK metK dat dat ARJ29508.1 ARJ29508.1 mtnN mtnN ARJ29718.1 ARJ29718.1 ARJ29772.1 ARJ29772.1 asd asd dapA dapA dapB dapB dapD dapD ARJ29777.1 ARJ29777.1 ARJ29778.1 ARJ29778.1 lysA lysA ARJ29851.1 ARJ29851.1 thrB thrB ARJ29853.1 ARJ29853.1 ARJ29854.1 ARJ29854.1 ARJ29855.1 ARJ29855.1 tdcB tdcB ARJ30633.1 ARJ30633.1 cysK cysK ARJ30704.1 ARJ30704.1 ARJ30885.1 ARJ30885.1 ARJ30749.1 ARJ30749.1 ARJ30750.1 ARJ30750.1 ARJ30751.1 ARJ30751.1 ARJ30752.1 ARJ30752.1 ARJ30801.1 ARJ30801.1 B6N84_12775 B6N84_12775
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARJ28603.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ARJ28788.1N-succinyldiaminopimelate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ARJ28828.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ARJ28829.1L-serine dehydratase, iron-sulfur-dependent subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (226 aa)
sdaAAL-serine dehydratase, iron-sulfur-dependent subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (298 aa)
ARJ28831.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
ARJ28884.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
luxSS-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (156 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (398 aa)
datD-amino-acid transaminase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. (281 aa)
ARJ29508.1Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
mtnN5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (228 aa)
ARJ29718.1L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
ARJ29772.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (400 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (329 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (241 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (239 aa)
ARJ29777.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
ARJ29778.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (358 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
ARJ29851.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa)
ARJ29853.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa)
ARJ29854.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
ARJ29855.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (457 aa)
tdcBSerine/threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (346 aa)
ARJ30633.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
cysKCysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
ARJ30704.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
ARJ30885.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ARJ30749.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ARJ30750.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
ARJ30751.1Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (612 aa)
ARJ30752.15-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (742 aa)
ARJ30801.1Homoserine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (322 aa)
B6N84_12775Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
Your Current Organism:
Staphylococcus lugdunensis
NCBI taxonomy Id: 28035
Other names: ATCC 43809, CCUG 25348, CIP 103642, DSM 4804, LMG 13346, LMG:13346, NCTC 12217, NRRL B-14774, S. lugdunensis, strain N860297
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