STRINGSTRING
ldh ldh ARJ28550.1 ARJ28550.1 ARJ28604.1 ARJ28604.1 ARJ28607.1 ARJ28607.1 ARJ28740.1 ARJ28740.1 ARJ28741.1 ARJ28741.1 mqo mqo ARJ28789.1 ARJ28789.1 ARJ28809.1 ARJ28809.1 ARJ28816.1 ARJ28816.1 ldh-2 ldh-2 ARJ28836.1 ARJ28836.1 ARJ28839.1 ARJ28839.1 lpdA lpdA mqo-2 mqo-2 ARJ29236.1 ARJ29236.1 leuA leuA ARJ29352.1 ARJ29352.1 fumC fumC pckA pckA ARJ29495.1 ARJ29495.1 ackA ackA ARJ29524.1 ARJ29524.1 accD accD accA accA ARJ29528.1 ARJ29528.1 ARJ29604.1 ARJ29604.1 ARJ29605.1 ARJ29605.1 ARJ29659.1 ARJ29659.1 accB accB ARJ29677.1 ARJ29677.1 ARJ29686.1 ARJ29686.1 ARJ29784.1 ARJ29784.1 ARJ29886.1 ARJ29886.1 ARJ29887.1 ARJ29887.1 ARJ29943.1 ARJ29943.1 ARJ30033.1 ARJ30033.1 ARJ30051.1 ARJ30051.1 ARJ30052.1 ARJ30052.1 ARJ30053.1 ARJ30053.1 pdhA pdhA mdh mdh pta pta
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (320 aa)
ARJ28550.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (748 aa)
ARJ28604.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
ARJ28607.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
ARJ28740.1acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
ARJ28741.1Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (874 aa)
mqoMalate dehydrogenase (quinone); Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
ARJ28789.1Lactate dehydrogenase; Catalyzes the formation of pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
ARJ28809.13-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (384 aa)
ARJ28816.1Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (579 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (321 aa)
ARJ28836.1Lactate dehydrogenase; Catalyzes the formation of pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
ARJ28839.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (497 aa)
lpdADihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
mqo-2Malate dehydrogenase (quinone); Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
ARJ29236.1Aldehyde dehydrogenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (516 aa)
ARJ29352.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (459 aa)
fumCClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
ARJ29495.1acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
ARJ29524.1NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
accDacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (285 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa)
ARJ29528.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (586 aa)
ARJ29604.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
ARJ29605.1acetyl-CoA carboxylase biotin carboxylase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
ARJ29659.1Hydroxyacylglutathione hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa)
ARJ29677.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
ARJ29686.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
ARJ29784.1Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
ARJ29886.12-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
ARJ29887.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
ARJ29943.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (381 aa)
ARJ30033.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
ARJ30051.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
ARJ30052.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
ARJ30053.1Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (370 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (314 aa)
ptaPhosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
Your Current Organism:
Staphylococcus lugdunensis
NCBI taxonomy Id: 28035
Other names: ATCC 43809, CCUG 25348, CIP 103642, DSM 4804, LMG 13346, LMG:13346, NCTC 12217, NRRL B-14774, S. lugdunensis, strain N860297
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