STRINGSTRING
CYME_CML168C CYME_CML168C CYME_CMT412C CYME_CMT412C CYME_CMS272C CYME_CMS272C CYME_CMD058C CYME_CMD058C CYME_CMJ055C CYME_CMJ055C CYME_CMH008C CYME_CMH008C CYME_CMN336C CYME_CMN336C CYME_CMT209C CYME_CMT209C CYME_CMF068C CYME_CMF068C CYME_CMH132C CYME_CMH132C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYME_CML168CBranched-chain alpha-keto acid decarboxylase E1 beta subunit. (447 aa)
CYME_CMT412CIsocitrate dehydrogenase subunit 1, mitochondrial. (414 aa)
CYME_CMS272CIsocitrate dehydrogenase subunit 2, mitochondrial. (388 aa)
CYME_CMD058CFumarate hydratase. (553 aa)
CYME_CMJ055C2-oxoglutarate dehydrogenase E2 component. (481 aa)
CYME_CMH008C2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (477 aa)
CYME_CMN336CAcetyl-CoA synthetase. (1026 aa)
CYME_CMT209CSuccinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (461 aa)
CYME_CMF068C2-oxoglutarate dehydrogenase, E1 component. (1066 aa)
CYME_CMH132CSuccinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (357 aa)
Your Current Organism:
Cyanidioschyzon merolae
NCBI taxonomy Id: 280699
Other names: C. merolae strain 10D, Cyanidioschyzon merolae strain 10D
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.