node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYME_CMB035C | CYME_CMH034C | M1VA03 | M1UQE4 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Probable DNA repair endonuclease XPF. | 0.511 |
CYME_CMB035C | FEN1 | M1VA03 | M1VBE4 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.927 |
CYME_CMC047C | CYME_CMH034C | M1V3X0 | M1UQE4 | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. | Probable DNA repair endonuclease XPF. | 0.576 |
CYME_CMC047C | FEN1 | M1V3X0 | M1VBE4 | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.531 |
CYME_CMD139C | CYME_CMI230C | M1V6T9 | M1V7V1 | Similar to endonuclease III. | Similar to endonuclease III. | 0.909 |
CYME_CMH034C | CYME_CMB035C | M1UQE4 | M1VA03 | Probable DNA repair endonuclease XPF. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.511 |
CYME_CMH034C | CYME_CMC047C | M1UQE4 | M1V3X0 | Probable DNA repair endonuclease XPF. | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. | 0.576 |
CYME_CMH034C | FEN1 | M1UQE4 | M1VBE4 | Probable DNA repair endonuclease XPF. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.560 |
CYME_CMH233C | CYME_CMK254C | M1VGP4 | M1USE0 | Probable tRNA splicing endonuclease subunit Sen34. | Probable tRNA splicing endonuclease subunit Sen54. | 0.768 |
CYME_CMH233C | CYME_CMN231C | M1VGP4 | M1VJ94 | Probable tRNA splicing endonuclease subunit Sen34. | Probable tRNA splicing endonuclease subunit Sen2. | 0.889 |
CYME_CMI230C | CYME_CMD139C | M1V7V1 | M1V6T9 | Similar to endonuclease III. | Similar to endonuclease III. | 0.909 |
CYME_CMI230C | CYME_CMQ271C | M1V7V1 | M1VKS0 | Similar to endonuclease III. | Similar to endonuclease. | 0.426 |
CYME_CMI230C | FEN1 | M1V7V1 | M1VBE4 | Similar to endonuclease III. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.602 |
CYME_CMK254C | CYME_CMH233C | M1USE0 | M1VGP4 | Probable tRNA splicing endonuclease subunit Sen54. | Probable tRNA splicing endonuclease subunit Sen34. | 0.768 |
CYME_CMK254C | CYME_CMN231C | M1USE0 | M1VJ94 | Probable tRNA splicing endonuclease subunit Sen54. | Probable tRNA splicing endonuclease subunit Sen2. | 0.898 |
CYME_CMK297C | FEN1 | M1VI00 | M1VBE4 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.501 |
CYME_CMN231C | CYME_CMH233C | M1VJ94 | M1VGP4 | Probable tRNA splicing endonuclease subunit Sen2. | Probable tRNA splicing endonuclease subunit Sen34. | 0.889 |
CYME_CMN231C | CYME_CMK254C | M1VJ94 | M1USE0 | Probable tRNA splicing endonuclease subunit Sen2. | Probable tRNA splicing endonuclease subunit Sen54. | 0.898 |
CYME_CMQ271C | CYME_CMI230C | M1VKS0 | M1V7V1 | Similar to endonuclease. | Similar to endonuclease III. | 0.426 |
CYME_CMT626C | FEN1 | M1UY40 | M1VBE4 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.501 |