STRINGSTRING
rfaE1 rfaE1 rfaE2 rfaE2 kdsA kdsA M6VK80_9LEPT M6VK80_9LEPT M6W188_9LEPT M6W188_9LEPT lptB lptB rpoN rpoN hprK hprK FF021_08125 FF021_08125 M6VRA6_9LEPT M6VRA6_9LEPT M6VJU6_9LEPT M6VJU6_9LEPT M6W0S9_9LEPT M6W0S9_9LEPT priA priA fmt fmt M6VDJ4_9LEPT M6VDJ4_9LEPT FF021_16535 FF021_16535 rimM rimM trmD trmD rnhB rnhB M6VEY5_9LEPT M6VEY5_9LEPT M6VD59_9LEPT M6VD59_9LEPT M6VR70_9LEPT M6VR70_9LEPT M6VF54_9LEPT M6VF54_9LEPT FF021_05550 FF021_05550 rfaD rfaD ptsP ptsP lpxC lpxC M6VIW0_9LEPT M6VIW0_9LEPT M6VW49_9LEPT M6VW49_9LEPT gmhA gmhA M6VA72_9LEPT M6VA72_9LEPT M6VAA5_9LEPT M6VAA5_9LEPT M6VKV3_9LEPT M6VKV3_9LEPT M6VBA3_9LEPT M6VBA3_9LEPT lpxK lpxK lpxA lpxA GCA_001568325_01621 GCA_001568325_01621 GCA_001568325_01623 GCA_001568325_01623 M6VCE1_9LEPT M6VCE1_9LEPT lnt-2 lnt-2 M6W1B7_9LEPT M6W1B7_9LEPT yidD yidD FF021_01265 FF021_01265 waaA waaA lpxD_2 lpxD_2 M6VZC6_9LEPT M6VZC6_9LEPT kdsB kdsB M6VC97_9LEPT M6VC97_9LEPT M6VHL4_9LEPT M6VHL4_9LEPT M6V5D2_9LEPT M6V5D2_9LEPT M6VSS5_9LEPT M6VSS5_9LEPT M6VHM5_9LEPT M6VHM5_9LEPT lpxB lpxB lpxD_1 lpxD_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfaE1Unannotated protein. (337 aa)
rfaE2Unannotated protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (158 aa)
kdsAUnannotated protein; Belongs to the KdsA family. (287 aa)
M6VK80_9LEPTUnannotated protein. (191 aa)
M6W188_9LEPTUnannotated protein. (453 aa)
lptBUnannotated protein. (235 aa)
rpoNUnannotated protein. (473 aa)
hprKUnannotated protein; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (321 aa)
FF021_08125Unannotated protein. (87 aa)
M6VRA6_9LEPTUnannotated protein. (596 aa)
M6VJU6_9LEPTUnannotated protein. (448 aa)
M6W0S9_9LEPTUnannotated protein. (277 aa)
priAUnannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (647 aa)
fmtUnannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa)
M6VDJ4_9LEPTUnannotated protein. (331 aa)
FF021_16535Unannotated protein; Belongs to the UPF0109 family. (76 aa)
rimMUnannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (176 aa)
trmDUnannotated protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (231 aa)
rnhBUnannotated protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (226 aa)
M6VEY5_9LEPTUnannotated protein. (247 aa)
M6VD59_9LEPTUnannotated protein. (87 aa)
M6VR70_9LEPTUnannotated protein. (394 aa)
M6VF54_9LEPTUnannotated protein; Belongs to the UPF0102 family. (116 aa)
FF021_05550Unannotated protein. (65 aa)
rfaDUnannotated protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose. (323 aa)
ptsPUnannotated protein; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (580 aa)
lpxCUnannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (301 aa)
M6VIW0_9LEPTUnannotated protein; Belongs to the SIS family. GutQ/KpsF subfamily. (322 aa)
M6VW49_9LEPTUnannotated protein. (479 aa)
gmhAUnannotated protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (195 aa)
M6VA72_9LEPTUnannotated protein. (258 aa)
M6VAA5_9LEPTUnannotated protein. (290 aa)
M6VKV3_9LEPTUnannotated protein. (796 aa)
M6VBA3_9LEPTUnannotated protein. (153 aa)
lpxKUnannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa)
lpxAUnannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (259 aa)
GCA_001568325_01621Unannotated protein. (187 aa)
GCA_001568325_01623Unannotated protein. (258 aa)
M6VCE1_9LEPTUnannotated protein. (386 aa)
lnt-2Unannotated protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (593 aa)
M6W1B7_9LEPTUnannotated protein. (300 aa)
yidDUnannotated protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (76 aa)
FF021_01265Unannotated protein. (236 aa)
waaAUnannotated protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (418 aa)
lpxD_2Unannotated protein. (352 aa)
M6VZC6_9LEPTUnannotated protein. (235 aa)
kdsBUnannotated protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
M6VC97_9LEPTUnannotated protein. (624 aa)
M6VHL4_9LEPTUnannotated protein. (522 aa)
M6V5D2_9LEPTUnannotated protein. (477 aa)
M6VSS5_9LEPTUnannotated protein. (81 aa)
M6VHM5_9LEPTUnannotated protein. (282 aa)
lpxBUnannotated protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (429 aa)
lpxD_1Unannotated protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (340 aa)
Your Current Organism:
Leptospira noguchii
NCBI taxonomy Id: 28182
Other names: ATCC 43288, DSM 21520, L. noguchii, strain CZ 214
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