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lpxD_1 lpxD_1 lpxB lpxB M6VG51_9LEPT M6VG51_9LEPT M6VX95_9LEPT M6VX95_9LEPT kdsB kdsB M6VDJ3_9LEPT M6VDJ3_9LEPT M6VZC6_9LEPT M6VZC6_9LEPT GCA_001568325_02920 GCA_001568325_02920 M6VIW0_9LEPT M6VIW0_9LEPT lpxC lpxC rfaD rfaD M6VCI1_9LEPT M6VCI1_9LEPT GCA_001568325_01130 GCA_001568325_01130 lpxK lpxK kdsA kdsA rfaE1 rfaE1 GCA_001568325_02917 GCA_001568325_02917 GCA_001568325_02770 GCA_001568325_02770 lpxD_2 lpxD_2 waaA waaA M6W1B7_9LEPT M6W1B7_9LEPT M6VK08_9LEPT M6VK08_9LEPT M6W181_9LEPT M6W181_9LEPT M6VIJ2_9LEPT M6VIJ2_9LEPT M6V4Q0_9LEPT M6V4Q0_9LEPT lpxA lpxA GCA_001568325_01623 GCA_001568325_01623 M6VJD6_9LEPT M6VJD6_9LEPT rfaE2 rfaE2 GCA_001568325_01621 GCA_001568325_01621 M6VKV3_9LEPT M6VKV3_9LEPT gmhA gmhA M6VMR9_9LEPT M6VMR9_9LEPT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpxD_1Unannotated protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (340 aa)
lpxBUnannotated protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (429 aa)
M6VG51_9LEPTUnannotated protein. (714 aa)
M6VX95_9LEPTUnannotated protein. (343 aa)
kdsBUnannotated protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
M6VDJ3_9LEPTUnannotated protein. (571 aa)
M6VZC6_9LEPTUnannotated protein. (235 aa)
GCA_001568325_02920Unannotated protein. (510 aa)
M6VIW0_9LEPTUnannotated protein; Belongs to the SIS family. GutQ/KpsF subfamily. (322 aa)
lpxCUnannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (301 aa)
rfaDUnannotated protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose. (323 aa)
M6VCI1_9LEPTUnannotated protein. (430 aa)
GCA_001568325_01130Unannotated protein. (292 aa)
lpxKUnannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa)
kdsAUnannotated protein; Belongs to the KdsA family. (287 aa)
rfaE1Unannotated protein. (337 aa)
GCA_001568325_02917Unannotated protein. (185 aa)
GCA_001568325_02770Unannotated protein. (598 aa)
lpxD_2Unannotated protein. (352 aa)
waaAUnannotated protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (418 aa)
M6W1B7_9LEPTUnannotated protein. (300 aa)
M6VK08_9LEPTUnannotated protein. (439 aa)
M6W181_9LEPTUnannotated protein. (343 aa)
M6VIJ2_9LEPTUnannotated protein. (609 aa)
M6V4Q0_9LEPTUnannotated protein. (264 aa)
lpxAUnannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (259 aa)
GCA_001568325_01623Unannotated protein. (258 aa)
M6VJD6_9LEPTUnannotated protein. (273 aa)
rfaE2Unannotated protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (158 aa)
GCA_001568325_01621Unannotated protein. (187 aa)
M6VKV3_9LEPTUnannotated protein. (796 aa)
gmhAUnannotated protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (195 aa)
M6VMR9_9LEPTUnannotated protein. (445 aa)
Your Current Organism:
Leptospira noguchii
NCBI taxonomy Id: 28182
Other names: ATCC 43288, DSM 21520, L. noguchii, strain CZ 214
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