| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFG36181.1 | cysE | SAMN04488517_10467 | SAMN04488517_103115 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Serine O-acetyltransferase. | 0.764 |
| SFG36181.1 | glyA2 | SAMN04488517_10467 | SAMN04488517_11824 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.715 |
| SFG36181.1 | sdaA | SAMN04488517_10467 | SAMN04488517_11825 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.746 |
| SFG36181.1 | serB | SAMN04488517_10467 | SAMN04488517_102301 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Phosphoserine phosphatase. | 0.780 |
| cysE | SFG36181.1 | SAMN04488517_103115 | SAMN04488517_10467 | Serine O-acetyltransferase. | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | 0.764 |
| cysE | cysK | SAMN04488517_103115 | SAMN04488517_10784 | Serine O-acetyltransferase. | Cysteine synthase A. | 0.973 |
| cysE | cysS | SAMN04488517_103115 | SAMN04488517_10753 | Serine O-acetyltransferase. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.981 |
| cysE | glyA2 | SAMN04488517_103115 | SAMN04488517_11824 | Serine O-acetyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.771 |
| cysE | sdaA | SAMN04488517_103115 | SAMN04488517_11825 | Serine O-acetyltransferase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.869 |
| cysE | serB | SAMN04488517_103115 | SAMN04488517_102301 | Serine O-acetyltransferase. | Phosphoserine phosphatase. | 0.891 |
| cysK | cysE | SAMN04488517_10784 | SAMN04488517_103115 | Cysteine synthase A. | Serine O-acetyltransferase. | 0.973 |
| cysK | cysS | SAMN04488517_10784 | SAMN04488517_10753 | Cysteine synthase A. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.898 |
| cysK | sdaA | SAMN04488517_10784 | SAMN04488517_11825 | Cysteine synthase A. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.450 |
| cysS | cysE | SAMN04488517_10753 | SAMN04488517_103115 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Serine O-acetyltransferase. | 0.981 |
| cysS | cysK | SAMN04488517_10753 | SAMN04488517_10784 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Cysteine synthase A. | 0.898 |
| cysS | glyA2 | SAMN04488517_10753 | SAMN04488517_11824 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.456 |
| cysS | sdaA | SAMN04488517_10753 | SAMN04488517_11825 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.401 |
| cysS | serB | SAMN04488517_10753 | SAMN04488517_102301 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phosphoserine phosphatase. | 0.472 |
| glyA2 | SFG36181.1 | SAMN04488517_11824 | SAMN04488517_10467 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | 0.715 |
| glyA2 | cysE | SAMN04488517_11824 | SAMN04488517_103115 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine O-acetyltransferase. | 0.771 |