STRINGSTRING
recC recC mtgA mtgA zipA zipA smc smc ccmI ccmI AOM03224.1 AOM03224.1 dsbE dsbE AOM02391.1 AOM02391.1 ccmE ccmE ccmD ccmD glmU glmU uvrD uvrD hupA hupA recG recG rep rep typA typA rapA rapA murJ murJ AOM00145.1 AOM00145.1 pilV pilV AOM00148.1 AOM00148.1 AOM00149.1 AOM00149.1 AOM00152.1 AOM00152.1 AOM00154.1 AOM00154.1 AOM00155.1 AOM00155.1 AOM00156.1 AOM00156.1 AOM02722.1 AOM02722.1 bamD bamD AOM00191.1 AOM00191.1 minC minC minD minD AOM00202.1 AOM00202.1 prfB prfB zapB zapB frr frr uppS uppS bamA bamA AOM00260.1 AOM00260.1 priA priA AOM02742.1 AOM02742.1 AOM00295.1 AOM00295.1 pilO pilO AOM00297.1 AOM00297.1 AOM00342.1 AOM00342.1 lptD lptD surA surA mltF mltF AOM00372.1 AOM00372.1 AOM00374.1 AOM00374.1 uppP uppP bamB bamB pilW pilW iscA iscA iscS iscS murI murI gyrA gyrA AOM00601.1 AOM00601.1 AOM00621.1 AOM00621.1 AOM00636.1 AOM00636.1 AOM00671.1 AOM00671.1 AOM00677.1 AOM00677.1 hupB hupB rplT rplT cpdA cpdA parE parE parC parC AOM02871.1 AOM02871.1 ureE ureE prfC prfC yaeJ yaeJ fliS fliS AOM01340.1 AOM01340.1 flhC flhC bamE bamE engB engB AOM02613.1 AOM02613.1 secB secB zapA zapA gyrB gyrB AOM03288.1 AOM03288.1 csgF csgF csgG csgG flhA flhA AOM01352.1 AOM01352.1 flgM flgM flgA flgA yhbY yhbY pilT pilT hfaB hfaB AOM02482.1 AOM02482.1 yeiU yeiU AOM03236.1 AOM03236.1 dnaB dnaB ccmA ccmA ccmB ccmB flgD flgD flgK flgK fliR fliR fliQ fliQ fliP fliP fliO fliO AOM01372.1 AOM01372.1 fliJ fliJ AOM01375.1 AOM01375.1 nfuA nfuA yidD yidD AOM01413.1 AOM01413.1 AOM01414.1 AOM01414.1 ccmC ccmC AOM01428.1 AOM01428.1 ybgF ybgF ruvB ruvB ruvA ruvA AOM01490.1 AOM01490.1 arsH arsH AOM01561.1 AOM01561.1 ddpX ddpX AOM01718.1 AOM01718.1 AOM03069.1 AOM03069.1 sufT sufT sufD sufD sufC sufC sufB sufB AOM01909.1 AOM01909.1 AOM03114.1 AOM03114.1 ctaG ctaG pqiB pqiB AOM03126.1 AOM03126.1 AOM01979.1 AOM01979.1 pilZ pilZ mltG mltG murB murB mfd mfd nagZ nagZ topA topA dacC dacC rlpA rlpA rodA rodA mrdA mrdA rsfS rsfS mpl mpl dsbD dsbD BFX80_13365 BFX80_13365 ftsZ ftsZ ftsQ ftsQ ddl ddl murC murC murG murG ftsW ftsW murD murD mraY mraY murF murF murE murE erpA erpA ftsI ftsI murA murA AOM02144.1 AOM02144.1 AOM02145.1 AOM02145.1 AOM02146.1 AOM02146.1 AOM03155.1 AOM03155.1 lptC lptC lptA lptA prfA prfA AOM03180.1 AOM03180.1 AOM02227.1 AOM02227.1 AOM02250.1 AOM02250.1 recD recD AOM02295.1 AOM02295.1 recB recB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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recCExodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1350 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (253 aa)
zipAHypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (419 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1172 aa)
ccmIC-type cytochrome biogenesis protein CcmI; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (445 aa)
AOM03224.1Cytochrome C; Possible subunit of a heme lyase. (168 aa)
dsbEThiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
AOM02391.1Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology. (666 aa)
ccmECytochrome c biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (165 aa)
ccmDHeme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (64 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
uvrDDNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (740 aa)
hupADNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (690 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (693 aa)
typAGTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
rapARNA polymerase-binding ATPase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (980 aa)
murJMurein biosynthesis integral membrane protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (532 aa)
AOM00145.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
pilVType IV pilus modification protein PilV; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (166 aa)
AOM00148.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (325 aa)
AOM00149.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (192 aa)
AOM00152.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
AOM00154.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (162 aa)
AOM00155.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (311 aa)
AOM00156.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (179 aa)
AOM02722.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
bamDOuter membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (267 aa)
AOM00191.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (940 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (260 aa)
minDSeptum site-determining protein MinD; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AOM00202.1Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (293 aa)
zapBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
uppSDi-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (247 aa)
bamAOuter membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (771 aa)
AOM00260.1Molecular chaperone Skp; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (755 aa)
AOM02742.1Pilus assembly protein PilM; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
AOM00295.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
pilOPilus assembly protein PilO; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AOM00297.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
AOM00342.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (399 aa)
lptDLPS biosynthesis protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (812 aa)
surAHypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (427 aa)
mltFLytic transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (488 aa)
AOM00372.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AOM00374.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (271 aa)
bamBOuter membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (386 aa)
pilWType IV pilus biogenesis/stability protein PilW; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
iscAIron-sulfur cluster assembly protein IscA; Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. (108 aa)
iscSIscS subfamily cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (284 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (937 aa)
AOM00601.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AOM00621.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (445 aa)
AOM00636.1DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AOM00671.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
AOM00677.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (297 aa)
hupBDNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
cpdAMetallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (244 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (626 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (758 aa)
AOM02871.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (195 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa)
yaeJpeptidyl-tRNA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
fliSFlagellar export chaperone FliS; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
AOM01340.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (519 aa)
flhCTranscriptional regulator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (177 aa)
bamEHypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (142 aa)
engBYihA family ribosome biogenesis GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (229 aa)
AOM02613.1Among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
secBProtein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (167 aa)
zapAHypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (120 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (805 aa)
AOM03288.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
csgFCurli production assembly/transport protein CsgF; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
csgGCurli production assembly/transport protein CsgG; Involved in the stability of the curlin proteins during assembly; involved in the secretion of the major curlin subunit CsgA across the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
flhAFlagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (698 aa)
AOM01352.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (157 aa)
flgMFlagellar biosynthesis anti-sigma factor FlgM; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (90 aa)
flgAFlagella basal body P-ring formation protein FlgA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (258 aa)
yhbYRibosome assembly protein YhbY; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
pilTTwitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
hfaBHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (225 aa)
AOM02482.1DNA starvation/stationary phase protection protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family. (159 aa)
yeiUPA-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AOM03236.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (459 aa)
ccmAHeme ABC transporter ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (237 aa)
ccmBHeme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (240 aa)
flgDFlagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein. (230 aa)
flgKFlagellar hook-associated protein FlgK; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
fliRFlagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (263 aa)
fliQEscS/YscS/HrcS family type III secretion system export apparatus protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (260 aa)
fliOFlagellar biosynthetic protein FliO; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (186 aa)
AOM01372.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (460 aa)
fliJFlagellar export protein FliJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AOM01375.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (299 aa)
nfuAFe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (196 aa)
yidDMembrane protein insertion efficiency factor YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (99 aa)
AOM01413.1Fe-S cluster assembly protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AOM01414.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (321 aa)
ccmCHeme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (265 aa)
AOM01428.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (379 aa)
ybgFTol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (256 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (347 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (204 aa)
AOM01490.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (940 aa)
arsHArsenical resistance protein ArsH; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AOM01561.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
ddpXD-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (253 aa)
AOM01718.1Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AOM03069.1K+/H+ antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
sufTPutative Fe-S cluster assembly protein SufT; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
sufDFe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
sufCFe-S cluster assembly ATPase SufC; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
sufBFe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
AOM01909.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (697 aa)
AOM03114.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
ctaGCytochrome c oxidase assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
pqiBMammalian cell entry protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
AOM03126.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
AOM01979.1DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (860 aa)
pilZPilus assembly protein PilZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
mltGBCR, YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (340 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (353 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1175 aa)
nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (364 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (880 aa)
dacCSerine-type D-Ala-D-Ala carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (400 aa)
rlpAHypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (342 aa)
rodARod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (382 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (650 aa)
rsfSRibosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (119 aa)
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (480 aa)
dsbDHypothetical protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (676 aa)
BFX80_13365Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (389 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (241 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (317 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (470 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (358 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (405 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (495 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (479 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (515 aa)
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (117 aa)
ftsICell division protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (553 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
AOM02144.1Cell division protein BolA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (84 aa)
AOM02145.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (125 aa)
AOM02146.1Toluene tolerance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
AOM03155.1ABC transporter maintaining outer membrane lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
lptCLPS export ABC transporter periplasmic protein LptC; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (227 aa)
lptALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (172 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (361 aa)
AOM03180.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
AOM02227.1LemA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AOM02250.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
recDExodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (719 aa)
AOM02295.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (616 aa)
recBHypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...] (788 aa)
Your Current Organism:
Cobetia marina
NCBI taxonomy Id: 28258
Other names: ATCC 25374, ATCC 29686 [[Halomonas halodurans]], Arthrobacter marinus, C. marina, CCUG 49558, CECT 4278, CIP 104765, DSM 4741, DSM 5160 [[Halomonas halodurans]], Deleya marina, Halomonas halodurans, Halomonas marina, IFO 15607 [[Halomonas halodurans]], JCM 21022, LMG 2217, LMG:2217, NBRC 102605, NBRC 15607 [[Halomonas halodurans]], Pseudomonas halodurans, Pseudomonas marina, strain 219
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