(13 nodes) Mixed, incl. Mitogen-activated protein (MAP) kinase p38-like, and Protein-tyrosine phosphatase, KIM-containing network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPN5	Protein tyrosine phosphatase non-receptor type 5. (526 aa)
	MAP2K3	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (348 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	MAPK12	Mitogen-activated protein kinase. (361 aa)
	PTPN7	Protein tyrosine phosphatase non-receptor type 7. (364 aa)
	dusp3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (398 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	PTPRR	Protein tyrosine phosphatase receptor type R. (658 aa)
	map2k6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAP2K3	MAPK11	ENSACAP00000001724	ENSACAP00000001802	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.984
MAP2K3	MAPK12	ENSACAP00000001724	ENSACAP00000001910	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.974
MAP2K3	MAPK13	ENSACAP00000001724	ENSACAP00000016684	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.974
MAP2K3	MAPK14	ENSACAP00000001724	ENSACAP00000016739	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.984
MAP2K3	MAPK3	ENSACAP00000001724	ENSACAP00000014825	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.965
MAP2K3	MAPKAPK2	ENSACAP00000001724	ENSACAP00000007702	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily.	0.547
MAP2K3	MAPKAPK3	ENSACAP00000001724	ENSACAP00000007073	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.552
MAP2K3	map2k6	ENSACAP00000001724	ENSACAP00000023446	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.901
MAPK11	MAP2K3	ENSACAP00000001802	ENSACAP00000001724	Mitogen-activated protein kinase.	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.984
MAPK11	MAPK12	ENSACAP00000001802	ENSACAP00000001910	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.610
MAPK11	MAPK13	ENSACAP00000001802	ENSACAP00000016684	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.601
MAPK11	MAPK3	ENSACAP00000001802	ENSACAP00000014825	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.937
MAPK11	MAPKAPK2	ENSACAP00000001802	ENSACAP00000007702	Mitogen-activated protein kinase.	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily.	0.991
MAPK11	MAPKAPK3	ENSACAP00000001802	ENSACAP00000007073	Mitogen-activated protein kinase.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.980
MAPK11	PTPN5	ENSACAP00000001802	ENSACAP00000000066	Mitogen-activated protein kinase.	Protein tyrosine phosphatase non-receptor type 5.	0.930
MAPK11	PTPN7	ENSACAP00000001802	ENSACAP00000004268	Mitogen-activated protein kinase.	Protein tyrosine phosphatase non-receptor type 7.	0.951
MAPK11	PTPRR	ENSACAP00000001802	ENSACAP00000017883	Mitogen-activated protein kinase.	Protein tyrosine phosphatase receptor type R.	0.953
MAPK11	dusp3	ENSACAP00000001802	ENSACAP00000004668	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.930
MAPK11	map2k6	ENSACAP00000001802	ENSACAP00000023446	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.984
MAPK12	MAP2K3	ENSACAP00000001910	ENSACAP00000001724	Mitogen-activated protein kinase.	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.974