(21 nodes) Retromer complex, and Phox homology network (Anolis carolinensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OTULIN	OTU deubiquitinase with linear linkage specificity. (335 aa)
	SNX7	Sorting nexin 7. (473 aa)
	VPS26B	VPS26, retromer complex component B. (336 aa)
	H9G4V0_ANOCA	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
	vps29	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
	SNX6	Sorting nexin; Involved in several stages of intracellular trafficking. (406 aa)
	LOC100553862	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (185 aa)
	SNX2	Sorting nexin 2. (519 aa)
	SORCS3	Sortilin related VPS10 domain containing receptor 3. (736 aa)
	SNX3	Sorting nexin 3. (163 aa)
	SNX1	Sorting nexin 1. (474 aa)
	TBC1D5	TBC1 domain family member 5. (739 aa)
	SNX27	Sorting nexin 27. (442 aa)
	SNX8	Sorting nexin 8. (432 aa)
	VPS26A	VPS26, retromer complex component A. (351 aa)
	VPS35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (838 aa)
	SNX5	Sorting nexin; Involved in several stages of intracellular trafficking. (405 aa)
	SNX12	Sorting nexin 12. (162 aa)
	SNX31	Sorting nexin 31. (436 aa)
	SNX30	Sorting nexin family member 30. (441 aa)
	SNX4	Sorting nexin 4. (476 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H9G4V0_ANOCA	LOC100553862	ENSACAP00000001153	ENSACAP00000002711	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.544
H9G4V0_ANOCA	SNX1	ENSACAP00000001153	ENSACAP00000006787	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 1.	0.843
H9G4V0_ANOCA	SNX12	ENSACAP00000001153	ENSACAP00000014969	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 12.	0.831
H9G4V0_ANOCA	SNX2	ENSACAP00000001153	ENSACAP00000003450	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 2.	0.847
H9G4V0_ANOCA	SNX27	ENSACAP00000001153	ENSACAP00000008596	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 27.	0.441
H9G4V0_ANOCA	SNX3	ENSACAP00000001153	ENSACAP00000005859	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 3.	0.831
H9G4V0_ANOCA	SNX30	ENSACAP00000001153	ENSACAP00000017120	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin family member 30.	0.534
H9G4V0_ANOCA	SNX4	ENSACAP00000001153	ENSACAP00000022499	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 4.	0.593
H9G4V0_ANOCA	SNX5	ENSACAP00000001153	ENSACAP00000013916	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.582
H9G4V0_ANOCA	SNX6	ENSACAP00000001153	ENSACAP00000002455	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.582
H9G4V0_ANOCA	SNX7	ENSACAP00000001153	ENSACAP00000000624	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 7.	0.534
H9G4V0_ANOCA	SNX8	ENSACAP00000001153	ENSACAP00000008851	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 8.	0.687
H9G4V0_ANOCA	TBC1D5	ENSACAP00000001153	ENSACAP00000007759	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	TBC1 domain family member 5.	0.825
H9G4V0_ANOCA	VPS26A	ENSACAP00000001153	ENSACAP00000009568	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	VPS26, retromer complex component A.	0.958
H9G4V0_ANOCA	VPS26B	ENSACAP00000001153	ENSACAP00000000916	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	VPS26, retromer complex component B.	0.936
H9G4V0_ANOCA	VPS35	ENSACAP00000001153	ENSACAP00000013183	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.968
LOC100553862	H9G4V0_ANOCA	ENSACAP00000002711	ENSACAP00000001153	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.544
LOC100553862	SNX1	ENSACAP00000002711	ENSACAP00000006787	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 1.	0.843
LOC100553862	SNX12	ENSACAP00000002711	ENSACAP00000014969	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 12.	0.831
LOC100553862	SNX2	ENSACAP00000002711	ENSACAP00000003450	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin 2.	0.847