(12 nodes) NADPH oxidase complex, and FAD-binding 8 network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOX5	NADPH oxidase 5. (737 aa)
	Noxo1	SH3 domain-containing protein. (66 aa)
	NOX3	NADPH oxidase 3. (568 aa)
	H9GBP2_ANOCA	Uncharacterized protein. (276 aa)
	CYBA	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (186 aa)
	DUOX2	Dual oxidase 2. (1534 aa)
	CYBB	Cytochrome b-245 beta chain. (521 aa)
	NOX4	NADPH oxidase 4. (581 aa)
	ncf2	Uncharacterized protein. (545 aa)
	NCF4	Neutrophil cytosolic factor 4. (348 aa)
	NCF1	Neutrophil cytosolic factor 1. (195 aa)
	LOC103282746	SH3 domain-containing protein. (143 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYBA	CYBB	ENSACAP00000006491	ENSACAP00000014601	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Cytochrome b-245 beta chain.	0.890
CYBA	DUOX2	ENSACAP00000006491	ENSACAP00000006548	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Dual oxidase 2.	0.776
CYBA	LOC103282746	ENSACAP00000006491	ENSACAP00000021163	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	SH3 domain-containing protein.	0.795
CYBA	NCF1	ENSACAP00000006491	ENSACAP00000018714	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 1.	0.943
CYBA	NCF4	ENSACAP00000006491	ENSACAP00000018582	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 4.	0.924
CYBA	NOX3	ENSACAP00000006491	ENSACAP00000005110	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase 3.	0.961
CYBA	NOX4	ENSACAP00000006491	ENSACAP00000014675	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase 4.	0.976
CYBA	NOX5	ENSACAP00000006491	ENSACAP00000001723	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase 5.	0.916
CYBA	Noxo1	ENSACAP00000006491	ENSACAP00000002329	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	SH3 domain-containing protein.	0.886
CYBA	ncf2	ENSACAP00000006491	ENSACAP00000014871	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Uncharacterized protein.	0.863
CYBB	CYBA	ENSACAP00000014601	ENSACAP00000006491	Cytochrome b-245 beta chain.	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	0.890
CYBB	H9GBP2_ANOCA	ENSACAP00000014601	ENSACAP00000006470	Cytochrome b-245 beta chain.	Uncharacterized protein.	0.572
CYBB	LOC103282746	ENSACAP00000014601	ENSACAP00000021163	Cytochrome b-245 beta chain.	SH3 domain-containing protein.	0.573
CYBB	NCF1	ENSACAP00000014601	ENSACAP00000018714	Cytochrome b-245 beta chain.	Neutrophil cytosolic factor 1.	0.701
CYBB	NCF4	ENSACAP00000014601	ENSACAP00000018582	Cytochrome b-245 beta chain.	Neutrophil cytosolic factor 4.	0.738
CYBB	NOX3	ENSACAP00000014601	ENSACAP00000005110	Cytochrome b-245 beta chain.	NADPH oxidase 3.	0.550
CYBB	NOX4	ENSACAP00000014601	ENSACAP00000014675	Cytochrome b-245 beta chain.	NADPH oxidase 4.	0.844
CYBB	Noxo1	ENSACAP00000014601	ENSACAP00000002329	Cytochrome b-245 beta chain.	SH3 domain-containing protein.	0.647
CYBB	ncf2	ENSACAP00000014601	ENSACAP00000014871	Cytochrome b-245 beta chain.	Uncharacterized protein.	0.715
DUOX2	CYBA	ENSACAP00000006548	ENSACAP00000006491	Dual oxidase 2.	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	0.776