STRINGSTRING
PPP2R5C PPP2R5C lcmt2 lcmt2 CACNG4 CACNG4 LCMT1 LCMT1 PPP6C PPP6C PPP2R3C PPP2R3C PPP2CA PPP2CA PPP2CB PPP2CB PPP4R3B PPP4R3B PPP4R1 PPP4R1 PPP4R4 PPP4R4 ppp2r2c ppp2r2c PPP2R5D PPP2R5D PPP2R2A PPP2R2A TRMT5 TRMT5 PPP2R2D PPP2R2D igbp1 igbp1 FNBP4 FNBP4 PPME1 PPME1 PPP4R3A PPP4R3A PPP2R1A PPP2R1A TIPRL TIPRL TYW3 TYW3 CACNG5 CACNG5 PPP2R3B PPP2R3B PTPA PTPA PPEF2 PPEF2 PPP2R2B PPP2R2B LOC100556649 LOC100556649 PPP4R2 PPP4R2 PPP4C PPP4C PPP2R5E PPP2R5E CACNG8 CACNG8 OCLN OCLN PPP2R5A PPP2R5A PPP1R1A PPP1R1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (579 aa)
lcmt2Uncharacterized protein. (263 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (308 aa)
LCMT1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (331 aa)
PPP6CSerine/threonine-protein phosphatase. (279 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (450 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PPP4R3BSMK-1 domain-containing protein. (820 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (953 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (765 aa)
ppp2r2cSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
PPP2R5DSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (618 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (448 aa)
TRMT5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (510 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (454 aa)
igbp1Uncharacterized protein. (359 aa)
FNBP4Formin binding protein 4. (961 aa)
PPME1Protein phosphatase methylesterase 1. (214 aa)
PPP4R3AProtein phosphatase 4 regulatory subunit 3A. (816 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (614 aa)
TIPRLTOR signaling pathway regulator. (268 aa)
TYW3tRNA-yW synthesizing protein 3 homolog. (267 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (271 aa)
PPP2R3BProtein phosphatase 2 regulatory subunit B''beta. (533 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (285 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (707 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
LOC100556649WRNPLPNID domain-containing protein. (938 aa)
PPP4R2Protein phosphatase 4 regulatory subunit 2. (406 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
PPP2R5ESerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (467 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (368 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (524 aa)
PPP2R5ASerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (499 aa)
PPP1R1AProtein phosphatase 1 regulatory inhibitor subunit 1A. (189 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.