(5 nodes) Mixed, incl. Glutamate receptor clustering, and Cornichon network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TBC1D12	TBC1 domain family member 12. (312 aa)
	LRRTM3	Leucine rich repeat transmembrane neuronal 3. (574 aa)
	CCDC167	Coiled-coil domain containing 167. (97 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (519 aa)
	CNIH3	Cornichon family AMPA receptor auxiliary protein 3. (160 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC167	LRRTM4	ENSACAP00000014077	ENSACAP00000017794	Coiled-coil domain containing 167.	Leucine rich repeat transmembrane neuronal 4.	0.556
CNIH3	LRRTM4	ENSACAP00000022223	ENSACAP00000017794	Cornichon family AMPA receptor auxiliary protein 3.	Leucine rich repeat transmembrane neuronal 4.	0.706
LRRTM3	TBC1D12	ENSACAP00000010466	ENSACAP00000007573	Leucine rich repeat transmembrane neuronal 3.	TBC1 domain family member 12.	0.737
LRRTM4	CCDC167	ENSACAP00000017794	ENSACAP00000014077	Leucine rich repeat transmembrane neuronal 4.	Coiled-coil domain containing 167.	0.556
LRRTM4	CNIH3	ENSACAP00000017794	ENSACAP00000022223	Leucine rich repeat transmembrane neuronal 4.	Cornichon family AMPA receptor auxiliary protein 3.	0.706
TBC1D12	LRRTM3	ENSACAP00000007573	ENSACAP00000010466	TBC1 domain family member 12.	Leucine rich repeat transmembrane neuronal 3.	0.737