(26 nodes) Serpin domain, and Fibrinolysis network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100553524	Uncharacterized protein. (350 aa)
	SERPIND1	Serpin family D member 1; Belongs to the serpin family. (492 aa)
	PLG	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (801 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (612 aa)
	SERPINA10	Serpin family A member 10; Belongs to the serpin family. (379 aa)
	LOC100562920	SERPIN domain-containing protein; Belongs to the serpin family. (438 aa)
	LOC100560417	SERPIN domain-containing protein; Belongs to the serpin family. (386 aa)
	LOC100560613	SERPIN domain-containing protein; Belongs to the serpin family. (435 aa)
	ITIH2	Inter-alpha-trypsin inhibitor heavy chain 2. (921 aa)
	G1KDZ2_ANOCA	SERPIN domain-containing protein; Belongs to the serpin family. (391 aa)
	FGL1	Fibrinogen like 1. (313 aa)
	AHSG	Alpha 2-HS glycoprotein. (360 aa)
	F13B	Coagulation factor XIII B chain. (654 aa)
	F9	Coagulation factor IX. (402 aa)
	SERPINC1	Serpin family C member 1; Belongs to the serpin family. (467 aa)
	FGG	Fibrinogen gamma chain. (436 aa)
	FGA	Fibrinogen alpha chain. (739 aa)
	FGB	Fibrinogen beta chain. (500 aa)
	SERPINB5	Serpin family B member 5; Belongs to the serpin family. (378 aa)
	H9GPG8_ANOCA	SERPIN domain-containing protein; Belongs to the serpin family. (395 aa)
	LOC100555089	Uncharacterized protein. (298 aa)
	HRG	Histidine rich glycoprotein. (544 aa)
	LOC100560217	SERPIN domain-containing protein; Belongs to the serpin family. (428 aa)
	c8g	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (137 aa)
	LOC100564642	Uncharacterized protein. (1493 aa)
	LOC100563702	SERPIN domain-containing protein; Belongs to the serpin family. (375 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSG	FGA	ENSACAP00000007726	ENSACAP00000015390	Alpha 2-HS glycoprotein.	Fibrinogen alpha chain.	0.954
AHSG	FGB	ENSACAP00000007726	ENSACAP00000015416	Alpha 2-HS glycoprotein.	Fibrinogen beta chain.	0.785
AHSG	FGG	ENSACAP00000007726	ENSACAP00000015388	Alpha 2-HS glycoprotein.	Fibrinogen gamma chain.	0.886
AHSG	HRG	ENSACAP00000007726	ENSACAP00000019612	Alpha 2-HS glycoprotein.	Histidine rich glycoprotein.	0.703
AHSG	ITIH2	ENSACAP00000007726	ENSACAP00000004629	Alpha 2-HS glycoprotein.	Inter-alpha-trypsin inhibitor heavy chain 2.	0.509
AHSG	LOC100553524	ENSACAP00000007726	ENSACAP00000001274	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.758
AHSG	LOC100555089	ENSACAP00000007726	ENSACAP00000017981	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.758
AHSG	LOC100564642	ENSACAP00000007726	ENSACAP00000020699	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.450
AHSG	PLG	ENSACAP00000007726	ENSACAP00000003302	Alpha 2-HS glycoprotein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.923
AHSG	SERPINA10	ENSACAP00000007726	ENSACAP00000003935	Alpha 2-HS glycoprotein.	Serpin family A member 10; Belongs to the serpin family.	0.459
AHSG	SERPINC1	ENSACAP00000007726	ENSACAP00000015125	Alpha 2-HS glycoprotein.	Serpin family C member 1; Belongs to the serpin family.	0.762
AHSG	SERPIND1	ENSACAP00000007726	ENSACAP00000002155	Alpha 2-HS glycoprotein.	Serpin family D member 1; Belongs to the serpin family.	0.459
AHSG	c8g	ENSACAP00000007726	ENSACAP00000020075	Alpha 2-HS glycoprotein.	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.	0.880
AHSG	f2	ENSACAP00000007726	ENSACAP00000003746	Alpha 2-HS glycoprotein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.967
F13B	F9	ENSACAP00000009109	ENSACAP00000014356	Coagulation factor XIII B chain.	Coagulation factor IX.	0.522
F13B	FGA	ENSACAP00000009109	ENSACAP00000015390	Coagulation factor XIII B chain.	Fibrinogen alpha chain.	0.928
F13B	FGB	ENSACAP00000009109	ENSACAP00000015416	Coagulation factor XIII B chain.	Fibrinogen beta chain.	0.817
F13B	FGG	ENSACAP00000009109	ENSACAP00000015388	Coagulation factor XIII B chain.	Fibrinogen gamma chain.	0.798
F13B	HRG	ENSACAP00000009109	ENSACAP00000019612	Coagulation factor XIII B chain.	Histidine rich glycoprotein.	0.763
F13B	PLG	ENSACAP00000009109	ENSACAP00000003302	Coagulation factor XIII B chain.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.479