(17 nodes) Complement activation network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MASP1	Mannan binding lectin serine peptidase 1. (696 aa)
	SERPING1	Serpin family G member 1; Belongs to the serpin family. (483 aa)
	C1R	Complement C1r; Belongs to the peptidase S1 family. (719 aa)
	LOC100558615	Uncharacterized protein; Belongs to the peptidase S1 family. (690 aa)
	COLEC10	Collectin subfamily member 10. (273 aa)
	LOC100565791	Uncharacterized protein. (384 aa)
	LOC100559226	Pentaxin. (226 aa)
	cfi	Uncharacterized protein; Belongs to the peptidase S1 family. (577 aa)
	CFP	Complement factor properdin. (464 aa)
	C3AR1	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (469 aa)
	Cfb	Uncharacterized protein; Belongs to the peptidase S1 family. (1108 aa)
	LOC100554736	Uncharacterized protein. (1719 aa)
	c3	Uncharacterized protein. (1655 aa)
	COLEC11	Collectin subfamily member 11. (285 aa)
	LOC100566600	NTR domain-containing protein. (1638 aa)
	H9GUG9_ANOCA	Uncharacterized protein. (579 aa)
	LOC100560720	Uncharacterized protein; Belongs to the peptidase S1 family. (431 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1R	CFP	ENSACAP00000007352	ENSACAP00000010758	Complement C1r; Belongs to the peptidase S1 family.	Complement factor properdin.	0.407
C1R	COLEC10	ENSACAP00000007352	ENSACAP00000008306	Complement C1r; Belongs to the peptidase S1 family.	Collectin subfamily member 10.	0.495
C1R	COLEC11	ENSACAP00000007352	ENSACAP00000016647	Complement C1r; Belongs to the peptidase S1 family.	Collectin subfamily member 11.	0.586
C1R	Cfb	ENSACAP00000007352	ENSACAP00000011394	Complement C1r; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.432
C1R	LOC100554736	ENSACAP00000007352	ENSACAP00000012781	Complement C1r; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.774
C1R	LOC100558615	ENSACAP00000007352	ENSACAP00000007914	Complement C1r; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.978
C1R	LOC100559226	ENSACAP00000007352	ENSACAP00000009890	Complement C1r; Belongs to the peptidase S1 family.	Pentaxin.	0.402
C1R	LOC100560720	ENSACAP00000007352	ENSACAP00000021268	Complement C1r; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.977
C1R	LOC100566600	ENSACAP00000007352	ENSACAP00000017074	Complement C1r; Belongs to the peptidase S1 family.	NTR domain-containing protein.	0.482
C1R	MASP1	ENSACAP00000007352	ENSACAP00000006779	Complement C1r; Belongs to the peptidase S1 family.	Mannan binding lectin serine peptidase 1.	0.416
C1R	SERPING1	ENSACAP00000007352	ENSACAP00000007015	Complement C1r; Belongs to the peptidase S1 family.	Serpin family G member 1; Belongs to the serpin family.	0.924
C1R	c3	ENSACAP00000007352	ENSACAP00000014905	Complement C1r; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.482
C3AR1	CFP	ENSACAP00000011037	ENSACAP00000010758	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	Complement factor properdin.	0.547
C3AR1	LOC100554736	ENSACAP00000011037	ENSACAP00000012781	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.662
C3AR1	LOC100566600	ENSACAP00000011037	ENSACAP00000017074	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	NTR domain-containing protein.	0.478
C3AR1	SERPING1	ENSACAP00000011037	ENSACAP00000007015	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	Serpin family G member 1; Belongs to the serpin family.	0.488
C3AR1	c3	ENSACAP00000011037	ENSACAP00000014905	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.945
C3AR1	cfi	ENSACAP00000011037	ENSACAP00000009904	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.446
CFP	C1R	ENSACAP00000010758	ENSACAP00000007352	Complement factor properdin.	Complement C1r; Belongs to the peptidase S1 family.	0.407
CFP	C3AR1	ENSACAP00000010758	ENSACAP00000011037	Complement factor properdin.	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.547