(45 nodes) Mixed, incl. Hyaluronidase, and ERAP1-like C-terminal domain network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NUCB2	Nucleobindin 2. (468 aa)
	LOC100567856	Hyaluronidase. (445 aa)
	G1K984_ANOCA	Hyaluronidase. (314 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (463 aa)
	SLC6A19	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (637 aa)
	LOC100559926	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (388 aa)
	AGTR2	Angiotensin II receptor type 2. (383 aa)
	NFXL1	Nuclear transcription factor, X-box binding like 1. (886 aa)
	LOC100558791	Hyaluronidase. (500 aa)
	AGTR1	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	NPEPPS	Aminopeptidase. (877 aa)
	REN	Renin; Belongs to the peptidase A1 family. (398 aa)
	LOC100554696	C-type lectin domain-containing protein. (160 aa)
	LVRN	Aminopeptidase. (986 aa)
	HYAL2	Hyaluronidase. (474 aa)
	HYAL3	Hyaluronidase. (468 aa)
	TWIST2	Twist family bHLH transcription factor 2. (161 aa)
	ENPEP	Aminopeptidase. (945 aa)
	ARHGAP24	Rho GTPase activating protein 24. (659 aa)
	LNPEP	Leucyl and cystinyl aminopeptidase. (1024 aa)
	ERAP1	Aminopeptidase. (929 aa)
	ELF5	E74 like ETS transcription factor 5. (266 aa)
	ace	Angiotensin-converting enzyme. (1305 aa)
	SLC6A20	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
	G1KQ98_ANOCA	Phospholipase A2. (806 aa)
	LOC100561409	Phospholipase A2. (779 aa)
	LOC100560813	Phospholipase A2. (763 aa)
	G1KQL9_ANOCA	Phospholipase A2. (779 aa)
	ACE2	Angiotensin-converting enzyme. (814 aa)
	cltrn	Collectrin domain-containing protein. (227 aa)
	AOAH	Acyloxyacyl hydrolase. (533 aa)
	HYAL4	Hyaluronidase. (478 aa)
	CRISP3	Cysteine rich secretory protein 3; Belongs to the CRISP family. (241 aa)
	HYAL1	Hyaluronidase. (444 aa)
	TBC1D4	TBC1 domain family member 4. (1150 aa)
	G1KY07_ANOCA	Fibrinogen C-terminal domain-containing protein. (353 aa)
	LOC100560819	G_PROTEIN_RECEP_F1_2 domain-containing protein. (317 aa)
	LOC100557286	COesterase domain-containing protein. (568 aa)
	LOC100563524	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (549 aa)
	LOC103281523	G_PROTEIN_RECEP_F1_2 domain-containing protein. (339 aa)
	LOC100564696	C-type lectin domain-containing protein. (140 aa)
	LOC100566793	Uncharacterized protein. (1660 aa)
	LOC100564895	C-type lectin domain-containing protein. (179 aa)
	LOC103279558	C-type lectin domain-containing protein. (161 aa)
	LOC100554503	C-type lectin domain-containing protein. (202 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	AGT	ENSACAP00000016751	ENSACAP00000001655	Angiotensin-converting enzyme.	Angiotensinogen; Belongs to the serpin family.	0.915
ACE2	AGTR1	ENSACAP00000016751	ENSACAP00000006796	Angiotensin-converting enzyme.	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.510
ACE2	LNPEP	ENSACAP00000016751	ENSACAP00000012036	Angiotensin-converting enzyme.	Leucyl and cystinyl aminopeptidase.	0.443
ACE2	REN	ENSACAP00000016751	ENSACAP00000007721	Angiotensin-converting enzyme.	Renin; Belongs to the peptidase A1 family.	0.617
ACE2	SLC6A19	ENSACAP00000016751	ENSACAP00000001755	Angiotensin-converting enzyme.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.873
ACE2	SLC6A20	ENSACAP00000016751	ENSACAP00000014137	Angiotensin-converting enzyme.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.758
ACE2	ace	ENSACAP00000016751	ENSACAP00000012980	Angiotensin-converting enzyme.	Angiotensin-converting enzyme.	0.418
AGT	ACE2	ENSACAP00000001655	ENSACAP00000016751	Angiotensinogen; Belongs to the serpin family.	Angiotensin-converting enzyme.	0.915
AGT	AGTR1	ENSACAP00000001655	ENSACAP00000006796	Angiotensinogen; Belongs to the serpin family.	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.999
AGT	AGTR2	ENSACAP00000001655	ENSACAP00000004690	Angiotensinogen; Belongs to the serpin family.	Angiotensin II receptor type 2.	0.999
AGT	ENPEP	ENSACAP00000001655	ENSACAP00000010382	Angiotensinogen; Belongs to the serpin family.	Aminopeptidase.	0.793
AGT	ERAP1	ENSACAP00000001655	ENSACAP00000012320	Angiotensinogen; Belongs to the serpin family.	Aminopeptidase.	0.598
AGT	LNPEP	ENSACAP00000001655	ENSACAP00000012036	Angiotensinogen; Belongs to the serpin family.	Leucyl and cystinyl aminopeptidase.	0.720
AGT	LOC100560819	ENSACAP00000001655	ENSACAP00000021085	Angiotensinogen; Belongs to the serpin family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.943
AGT	LOC103281523	ENSACAP00000001655	ENSACAP00000022063	Angiotensinogen; Belongs to the serpin family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.455
AGT	LVRN	ENSACAP00000001655	ENSACAP00000007980	Angiotensinogen; Belongs to the serpin family.	Aminopeptidase.	0.747
AGT	NPEPPS	ENSACAP00000001655	ENSACAP00000007170	Angiotensinogen; Belongs to the serpin family.	Aminopeptidase.	0.748
AGT	REN	ENSACAP00000001655	ENSACAP00000007721	Angiotensinogen; Belongs to the serpin family.	Renin; Belongs to the peptidase A1 family.	0.819
AGT	ace	ENSACAP00000001655	ENSACAP00000012980	Angiotensinogen; Belongs to the serpin family.	Angiotensin-converting enzyme.	0.965
AGT	cltrn	ENSACAP00000001655	ENSACAP00000016753	Angiotensinogen; Belongs to the serpin family.	Collectrin domain-containing protein.	0.806