(48 nodes) Class B/2 (Secretin family receptors), and Dipeptidylpeptidase IV, N-terminal domain network (Anolis carolinensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCTR	Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (432 aa)
	CALCRL	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
	LOC100562512	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (298 aa)
	PLEKHN1	Pleckstrin homology domain containing N1. (697 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (490 aa)
	VIPR2	Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa)
	ANO6	Anoctamin. (913 aa)
	DPP10	Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (747 aa)
	ucn3	CRF domain-containing protein. (154 aa)
	LOC100556910	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (513 aa)
	RNPEP	Arginyl aminopeptidase. (716 aa)
	H9G9B1_ANOCA	Uncharacterized protein. (141 aa)
	pth1r	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (482 aa)
	VIP	Vasoactive intestinal peptide. (201 aa)
	CRHR2	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	LOC103279270	GLUCAGON domain-containing protein. (149 aa)
	ADCYAP1R1	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (505 aa)
	LOC100564129	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (440 aa)
	VIPR1	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (449 aa)
	PLSCR5	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (268 aa)
	LOC103278186	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
	RAMP3	Receptor activity modifying protein 3. (147 aa)
	CRHBP	Corticotropin releasing hormone binding protein. (405 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (172 aa)
	LOC100556423	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (430 aa)
	MCRIP1	MAPK regulated corepressor interacting protein 1. (97 aa)
	GCGR	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (500 aa)
	PTH2R	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (530 aa)
	ghrh	GLUCAGON domain-containing protein. (170 aa)
	CALCB	Calcitonin related polypeptide beta. (140 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
	GCG	Glucagon. (86 aa)
	RAMP2	Receptor activity modifying protein 2. (119 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (754 aa)
	RAMP1	Receptor activity modifying protein 1. (143 aa)
	LTBP2	Latent transforming growth factor beta binding protein 2. (1735 aa)
	CRH	Corticotropin releasing hormone. (202 aa)
	ADA	Adenosine deaminase. (360 aa)
	DHRS7C	Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
	GLP2R	Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (494 aa)
	IAPP	Islet amyloid polypeptide. (130 aa)
	crhr1	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (412 aa)
	PTHLH	Parathyroid hormone like hormone. (176 aa)
	Pth	Uncharacterized protein. (36 aa)
	fap	Uncharacterized protein; Belongs to the peptidase S9B family. (763 aa)
	SAYSD1	SAYSVFN motif domain containing 1. (181 aa)
	pth2	Uncharacterized protein. (214 aa)
	slamf8	IGv domain-containing protein. (337 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	DPP10	ENSACAP00000016622	ENSACAP00000002444	Adenosine deaminase.	Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.	0.453
ADA	DPP4	ENSACAP00000016622	ENSACAP00000014338	Adenosine deaminase.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.964
ADA	GCG	ENSACAP00000016622	ENSACAP00000013914	Adenosine deaminase.	Glucagon.	0.593
ADA	fap	ENSACAP00000016622	ENSACAP00000020919	Adenosine deaminase.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.593
ADCYAP1	ADCYAP1R1	ENSACAP00000008538	ENSACAP00000006216	Adenylate cyclase activating polypeptide 1.	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	0.998
ADCYAP1	CALCR	ENSACAP00000008538	ENSACAP00000013020	Adenylate cyclase activating polypeptide 1.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.565
ADCYAP1	CALCRL	ENSACAP00000008538	ENSACAP00000001103	Adenylate cyclase activating polypeptide 1.	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	CRH	ENSACAP00000008538	ENSACAP00000016393	Adenylate cyclase activating polypeptide 1.	Corticotropin releasing hormone.	0.481
ADCYAP1	CRHR2	ENSACAP00000008538	ENSACAP00000005627	Adenylate cyclase activating polypeptide 1.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	GCGR	ENSACAP00000008538	ENSACAP00000010491	Adenylate cyclase activating polypeptide 1.	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	GLP1R	ENSACAP00000008538	ENSACAP00000001897	Adenylate cyclase activating polypeptide 1.	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.631
ADCYAP1	GLP2R	ENSACAP00000008538	ENSACAP00000016714	Adenylate cyclase activating polypeptide 1.	Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	H9G9B1_ANOCA	ENSACAP00000008538	ENSACAP00000004528	Adenylate cyclase activating polypeptide 1.	Uncharacterized protein.	0.545
ADCYAP1	LOC100556423	ENSACAP00000008538	ENSACAP00000009320	Adenylate cyclase activating polypeptide 1.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	LOC100556910	ENSACAP00000008538	ENSACAP00000003878	Adenylate cyclase activating polypeptide 1.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	LOC100562512	ENSACAP00000008538	ENSACAP00000001325	Adenylate cyclase activating polypeptide 1.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	LOC100564129	ENSACAP00000008538	ENSACAP00000006343	Adenylate cyclase activating polypeptide 1.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.780
ADCYAP1	PTH2R	ENSACAP00000008538	ENSACAP00000010946	Adenylate cyclase activating polypeptide 1.	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.547
ADCYAP1	SCTR	ENSACAP00000008538	ENSACAP00000000908	Adenylate cyclase activating polypeptide 1.	Secretin receptor; Belongs to the G-protein coupled receptor 2 family.	0.823
ADCYAP1	VIPR1	ENSACAP00000008538	ENSACAP00000006503	Adenylate cyclase activating polypeptide 1.	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.951