(13 nodes) Protein repair, and Peroxiredoxin, C-terminal network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	txnip	Arrestin_N domain-containing protein. (124 aa)
	PRDX2	Peroxiredoxin 2. (198 aa)
	MSRB3	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (184 aa)
	prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (206 aa)
	PRDX4	Peroxiredoxin 4. (273 aa)
	ERP44	Endoplasmic reticulum protein 44. (392 aa)
	msra	PMSR domain-containing protein. (235 aa)
	GLRX	Glutaredoxin. (105 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	PRDX1	Peroxiredoxin 1. (199 aa)
	TXN2	Thioredoxin 2. (171 aa)
	G1KUA1_ANOCA	NDK domain-containing protein; Belongs to the NDK family. (119 aa)
	TXNDC8	Thioredoxin; Belongs to the thioredoxin family. (123 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERP44	PRDX1	ENSACAP00000008776	ENSACAP00000014849	Endoplasmic reticulum protein 44.	Peroxiredoxin 1.	0.595
ERP44	PRDX2	ENSACAP00000008776	ENSACAP00000003309	Endoplasmic reticulum protein 44.	Peroxiredoxin 2.	0.595
ERP44	PRDX4	ENSACAP00000008776	ENSACAP00000007342	Endoplasmic reticulum protein 44.	Peroxiredoxin 4.	0.886
ERP44	TXN	ENSACAP00000008776	ENSACAP00000012786	Endoplasmic reticulum protein 44.	Thioredoxin; Belongs to the thioredoxin family.	0.430
ERP44	msra	ENSACAP00000008776	ENSACAP00000009872	Endoplasmic reticulum protein 44.	PMSR domain-containing protein.	0.624
ERP44	prdx5	ENSACAP00000008776	ENSACAP00000006272	Endoplasmic reticulum protein 44.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.543
G1KUA1_ANOCA	GLRX	ENSACAP00000017404	ENSACAP00000012683	NDK domain-containing protein; Belongs to the NDK family.	Glutaredoxin.	0.677
G1KUA1_ANOCA	MSRB3	ENSACAP00000017404	ENSACAP00000003388	NDK domain-containing protein; Belongs to the NDK family.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.580
G1KUA1_ANOCA	PRDX1	ENSACAP00000017404	ENSACAP00000014849	NDK domain-containing protein; Belongs to the NDK family.	Peroxiredoxin 1.	0.837
G1KUA1_ANOCA	PRDX2	ENSACAP00000017404	ENSACAP00000003309	NDK domain-containing protein; Belongs to the NDK family.	Peroxiredoxin 2.	0.837
G1KUA1_ANOCA	PRDX4	ENSACAP00000017404	ENSACAP00000007342	NDK domain-containing protein; Belongs to the NDK family.	Peroxiredoxin 4.	0.837
G1KUA1_ANOCA	TXN2	ENSACAP00000017404	ENSACAP00000016094	NDK domain-containing protein; Belongs to the NDK family.	Thioredoxin 2.	0.757
G1KUA1_ANOCA	msra	ENSACAP00000017404	ENSACAP00000009872	NDK domain-containing protein; Belongs to the NDK family.	PMSR domain-containing protein.	0.940
G1KUA1_ANOCA	prdx5	ENSACAP00000017404	ENSACAP00000006272	NDK domain-containing protein; Belongs to the NDK family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.961
G1KUA1_ANOCA	txnip	ENSACAP00000017404	ENSACAP00000001174	NDK domain-containing protein; Belongs to the NDK family.	Arrestin_N domain-containing protein.	0.604
GLRX	G1KUA1_ANOCA	ENSACAP00000012683	ENSACAP00000017404	Glutaredoxin.	NDK domain-containing protein; Belongs to the NDK family.	0.677
GLRX	MSRB3	ENSACAP00000012683	ENSACAP00000003388	Glutaredoxin.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.568
GLRX	TXN	ENSACAP00000012683	ENSACAP00000012786	Glutaredoxin.	Thioredoxin; Belongs to the thioredoxin family.	0.707
GLRX	TXN2	ENSACAP00000012683	ENSACAP00000016094	Glutaredoxin.	Thioredoxin 2.	0.527
GLRX	TXNDC8	ENSACAP00000012683	ENSACAP00000023334	Glutaredoxin.	Thioredoxin; Belongs to the thioredoxin family.	0.700