(32 nodes) Mixed, incl. SMN complex, and Protein arginine N-methyltransferase network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Vwa8	Uncharacterized protein. (788 aa)
	ASTE1	Asteroid homolog 1. (712 aa)
	ANKS1A	Ankyrin repeat and sterile alpha motif domain containing 1A. (1222 aa)
	PRMT5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (639 aa)
	CLNS1A	Chloride nucleotide-sensitive channel 1A. (242 aa)
	GEMIN8	Gem nuclear organelle associated protein 8. (225 aa)
	PDCD2	Programmed cell death 2. (389 aa)
	FAM120B	Family with sequence similarity 120B. (825 aa)
	LOC100566534	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (453 aa)
	PRMT9	Protein arginine methyltransferase 9; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (838 aa)
	GEMIN5	Gem nuclear organelle associated protein 5. (1507 aa)
	GEMIN7	Gem nuclear organelle associated protein 7. (132 aa)
	PRMT1	Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (370 aa)
	GEMIN6	Gem nuclear organelle associated protein 6. (167 aa)
	DDX20	DEAD-box helicase 20; Belongs to the DEAD box helicase family. (752 aa)
	ZNF277	Zinc finger protein 277. (481 aa)
	G1KGW4_ANOCA	FHA domain-containing protein. (1533 aa)
	PRMT8	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (395 aa)
	BTG2	BTG anti-proliferation factor 2. (170 aa)
	LOC100553231	Tudor domain-containing protein. (279 aa)
	hirip3	CHZ domain-containing protein. (585 aa)
	PRMT7	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (688 aa)
	STRAP	Serine/threonine kinase receptor associated protein. (350 aa)
	PRMT3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (526 aa)
	GEMIN2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (265 aa)
	GEMIN4	Gem nuclear organelle associated protein 4. (1010 aa)
	pdcd2l	PDCD2_C domain-containing protein. (378 aa)
	G1KXH6_ANOCA	VWFA domain-containing protein. (370 aa)
	LOC100553792	Uncharacterized protein. (129 aa)
	WDR77	WD repeat domain 77. (324 aa)
	spata6l	SPATA6 domain-containing protein. (432 aa)
	R4GD68_ANOCA	Uncharacterized protein. (401 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASTE1	DDX20	ENSACAP00000001639	ENSACAP00000006167	Asteroid homolog 1.	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	0.486
ASTE1	GEMIN8	ENSACAP00000001639	ENSACAP00000001873	Asteroid homolog 1.	Gem nuclear organelle associated protein 8.	0.413
ASTE1	LOC100553231	ENSACAP00000001639	ENSACAP00000009875	Asteroid homolog 1.	Tudor domain-containing protein.	0.591
BTG2	PRMT1	ENSACAP00000009777	ENSACAP00000004792	BTG anti-proliferation factor 2.	Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.751
BTG2	PRMT8	ENSACAP00000009777	ENSACAP00000009131	BTG anti-proliferation factor 2.	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.470
CLNS1A	GEMIN2	ENSACAP00000001852	ENSACAP00000015604	Chloride nucleotide-sensitive channel 1A.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.412
CLNS1A	GEMIN5	ENSACAP00000001852	ENSACAP00000003886	Chloride nucleotide-sensitive channel 1A.	Gem nuclear organelle associated protein 5.	0.451
CLNS1A	LOC100553231	ENSACAP00000001852	ENSACAP00000009875	Chloride nucleotide-sensitive channel 1A.	Tudor domain-containing protein.	0.952
CLNS1A	PRMT5	ENSACAP00000001852	ENSACAP00000001752	Chloride nucleotide-sensitive channel 1A.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.991
CLNS1A	STRAP	ENSACAP00000001852	ENSACAP00000014144	Chloride nucleotide-sensitive channel 1A.	Serine/threonine kinase receptor associated protein.	0.544
CLNS1A	WDR77	ENSACAP00000001852	ENSACAP00000022481	Chloride nucleotide-sensitive channel 1A.	WD repeat domain 77.	0.984
CLNS1A	spata6l	ENSACAP00000001852	ENSACAP00000022920	Chloride nucleotide-sensitive channel 1A.	SPATA6 domain-containing protein.	0.926
DDX20	ASTE1	ENSACAP00000006167	ENSACAP00000001639	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	Asteroid homolog 1.	0.486
DDX20	FAM120B	ENSACAP00000006167	ENSACAP00000002589	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	Family with sequence similarity 120B.	0.486
DDX20	G1KGW4_ANOCA	ENSACAP00000006167	ENSACAP00000007498	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	FHA domain-containing protein.	0.486
DDX20	G1KXH6_ANOCA	ENSACAP00000006167	ENSACAP00000020099	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	VWFA domain-containing protein.	0.486
DDX20	GEMIN2	ENSACAP00000006167	ENSACAP00000015604	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.996
DDX20	GEMIN4	ENSACAP00000006167	ENSACAP00000015722	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	Gem nuclear organelle associated protein 4.	0.997
DDX20	GEMIN5	ENSACAP00000006167	ENSACAP00000003886	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	Gem nuclear organelle associated protein 5.	0.996
DDX20	GEMIN6	ENSACAP00000006167	ENSACAP00000005985	DEAD-box helicase 20; Belongs to the DEAD box helicase family.	Gem nuclear organelle associated protein 6.	0.939