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EPB41L5 EPB41L5 LOC100556863 LOC100556863 EZR EZR MYO6 MYO6 ASAP3 ASAP3 LOC100563818 LOC100563818 CIB3 CIB3 SH3YL1 SH3YL1 WIPF1 WIPF1 APPL1 APPL1 MKLN1 MKLN1 G1KEQ8_ANOCA G1KEQ8_ANOCA PDLIM7 PDLIM7 EPHA2 EPHA2 ARHGEF26 ARHGEF26 JCAD JCAD TLN2 TLN2 ROCK1 ROCK1 COBL COBL CIB1 CIB1 CFL1 CFL1 NF2 NF2 myo1h myo1h PLCG2 PLCG2 INPP5J INPP5J MTMR14 MTMR14 MTMR9 MTMR9 FAM107A FAM107A TLN1 TLN1 TLNRD1 TLNRD1 LOC100564889 LOC100564889 R4G9P8_ANOCA R4G9P8_ANOCA PLCG1 PLCG1 DBNL DBNL ITGA5 ITGA5 CAPG CAPG EPS8L3 EPS8L3 SPRY4 SPRY4 CLASP2 CLASP2 TLR4 TLR4 LOC100554572 LOC100554572 ARHGAP18 ARHGAP18 PSD PSD PSD3 PSD3 RASGRP2 RASGRP2 EPS8 EPS8 RAB22A RAB22A PIP5K1A PIP5K1A PLA2G4F PLA2G4F EPS8L2 EPS8L2 FRMD4B FRMD4B BAIAP2 BAIAP2 APPL2 APPL2 KIF18A KIF18A PACSIN1 PACSIN1 HIP1R HIP1R PACSIN2 PACSIN2 aif1 aif1 INPP5E INPP5E MYADM MYADM TESC TESC ARHGEF2 ARHGEF2 FGD2 FGD2 EPS8L1 EPS8L1 LIMA1 LIMA1 C2CD5 C2CD5 plekho1 plekho1 WASF2 WASF2 H9GQ96_ANOCA H9GQ96_ANOCA H9GR05_ANOCA H9GR05_ANOCA TIRAP TIRAP LOC100558191 LOC100558191 myo9b myo9b LOC103282689 LOC103282689 LOC103281908 LOC103281908 itgb3 itgb3 ptprj ptprj MYO10 MYO10 RASA1 RASA1 PLEK PLEK ALS2 ALS2 ARF6 ARF6 CLIP1 CLIP1 AIF1L AIF1L MTSS2 MTSS2 ITGAV ITGAV LOC100566976 LOC100566976 ITGB1BP1 ITGB1BP1 rps3 rps3 NME1-NME2 NME1-NME2 PSD2 PSD2 LOC100560688 LOC100560688 PDE9A PDE9A arhgap45 arhgap45 spata13 spata13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (737 aa)
LOC100556863Myotubularin phosphatase domain-containing protein. (551 aa)
EZREzrin. (586 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1263 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (723 aa)
LOC100563818Uncharacterized protein. (423 aa)
CIB3Calcium and integrin binding family member 3. (135 aa)
SH3YL1SH3 and SYLF domain containing 1. (336 aa)
WIPF1WAS/WASL interacting protein family member 1. (505 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
MKLN1Muskelin 1. (717 aa)
G1KEQ8_ANOCAUncharacterized protein. (226 aa)
PDLIM7PDZ and LIM domain 7. (452 aa)
EPHA2EPH receptor A2. (981 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (877 aa)
JCADJunctional cadherin 5 associated. (1339 aa)
TLN2Uncharacterized protein. (2256 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1357 aa)
COBLCordon-bleu WH2 repeat protein. (1398 aa)
CIB1Uncharacterized protein. (85 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
NF2Neurofibromin 2. (596 aa)
myo1hMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (323 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1263 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (692 aa)
MTMR14Myotubularin related protein 14. (624 aa)
MTMR9Myotubularin related protein 9. (555 aa)
FAM107AFamily with sequence similarity 107 member A. (175 aa)
TLN1Talin 1. (2356 aa)
TLNRD1Talin rod domain containing 1. (352 aa)
LOC100564889EF-hand domain-containing protein. (93 aa)
R4G9P8_ANOCAUncharacterized protein. (1180 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1283 aa)
DBNLDrebrin like. (484 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1032 aa)
CAPGCapping actin protein, gelsolin like. (349 aa)
EPS8L3EPS8 like 3. (596 aa)
SPRY4Sprouty RTK signaling antagonist 4. (300 aa)
CLASP2Cytoplasmic linker associated protein 2. (791 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (841 aa)
LOC100554572Uncharacterized protein. (209 aa)
ARHGAP18Rho GTPase activating protein 18. (710 aa)
PSDPleckstrin and Sec7 domain containing. (946 aa)
PSD3Pleckstrin and Sec7 domain containing 3. (336 aa)
RASGRP2RAS guanyl releasing protein 2. (277 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (845 aa)
RAB22ARAB22A, member RAS oncogene family. (194 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (490 aa)
PLA2G4FPhospholipase A2. (865 aa)
EPS8L2EPS8 like 2. (736 aa)
FRMD4BFERM domain containing 4B. (1034 aa)
BAIAP2BAI1 associated protein 2. (530 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (661 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (920 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (445 aa)
HIP1RHuntingtin interacting protein 1 related. (1063 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (482 aa)
aif1EF-hand domain-containing protein. (119 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (485 aa)
MYADMMyeloid associated differentiation marker. (272 aa)
TESCTescalcin. (214 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (383 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (637 aa)
EPS8L1EPS8 like 1. (715 aa)
LIMA1LIM domain and actin binding 1. (761 aa)
C2CD5C2 calcium dependent domain containing 5. (1081 aa)
plekho1PH domain-containing protein. (84 aa)
WASF2WASP family member 2. (495 aa)
H9GQ96_ANOCAI/LWEQ domain-containing protein. (149 aa)
H9GR05_ANOCAADF-H domain-containing protein. (328 aa)
TIRAPTIR domain containing adaptor protein. (215 aa)
LOC100558191IPPc domain-containing protein. (202 aa)
myo9bUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (800 aa)
LOC103282689IPPc domain-containing protein. (201 aa)
LOC103281908Phosphoinositide phospholipase C. (334 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (585 aa)
ptprjUncharacterized protein. (1332 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2006 aa)
RASA1RAS p21 protein activator 1. (1018 aa)
PLEKPleckstrin. (358 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1649 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1442 aa)
AIF1LAllograft inflammatory factor 1 like. (152 aa)
MTSS2MTSS I-BAR domain containing 2. (765 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1041 aa)
LOC100566976Phosphoinositide phospholipase C. (889 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
rps3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
NME1-NME2Nucleoside diphosphate kinase. (267 aa)
PSD2Pleckstrin and Sec7 domain containing 2. (707 aa)
LOC100560688Uncharacterized protein. (291 aa)
PDE9APhosphodiesterase. (539 aa)
arhgap45Rho GTPase activating protein 45. (981 aa)
spata13Uncharacterized protein. (1266 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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