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G1K855_ANOCA G1K855_ANOCA LOC100555851 LOC100555851 CACNA1E CACNA1E CACNG4 CACNG4 CACNG1 CACNG1 GOLM1 GOLM1 LOC100555312 LOC100555312 TRPC7 TRPC7 PKD2L1 PKD2L1 trpv5 trpv5 GRIN2A GRIN2A CATSPER3 CATSPER3 TRPV3 TRPV3 ITGAV ITGAV ORAI1 ORAI1 Ryr1 Ryr1 H9G6F5_ANOCA H9G6F5_ANOCA H9G738_ANOCA H9G738_ANOCA Ryr2 Ryr2 G1KC21_ANOCA G1KC21_ANOCA TRPM7 TRPM7 TMC2 TMC2 CATSPER4 CATSPER4 Cacna1a Cacna1a TRPC1 TRPC1 SLC24A5 SLC24A5 TPCN1 TPCN1 CACNA1G CACNA1G SLC24A3 SLC24A3 TRPM6 TRPM6 OPRM1 OPRM1 CACNB2 CACNB2 GPM6A GPM6A LOC100566721 LOC100566721 Pkd1 Pkd1 CACNA2D2 CACNA2D2 CACNA1I CACNA1I ORAI3 ORAI3 PKD1L3 PKD1L3 CALHM1 CALHM1 CACHD1 CACHD1 LOC100566195 LOC100566195 LOC100552814 LOC100552814 Catsper1 Catsper1 TRPM2 TRPM2 pkd1l2 pkd1l2 SLC24A4 SLC24A4 H9GEX9_ANOCA H9GEX9_ANOCA TMEM37 TMEM37 CACNA1S CACNA1S TRPM8 TRPM8 ITPR1 ITPR1 GRIN2B GRIN2B ANXA6 ANXA6 cacna2d4 cacna2d4 GRIN3A GRIN3A CACNG5 CACNG5 Cacna1d Cacna1d G1KLC7_ANOCA G1KLC7_ANOCA CACNA2D3 CACNA2D3 CACNA1B CACNA1B CACNA1C CACNA1C ITPR2 ITPR2 LOC100560693 LOC100560693 cacnb4 cacnb4 TRPC3 TRPC3 PKD2 PKD2 TRPC6 TRPC6 MCOLN3 MCOLN3 TRPM4 TRPM4 CACNA2D1 CACNA2D1 TMCO1 TMCO1 CACNA1F CACNA1F TRPC5 TRPC5 TRPV1 TRPV1 PANX1 PANX1 TRPA1 TRPA1 STIM2 STIM2 PKDREJ PKDREJ H9GMB4_ANOCA H9GMB4_ANOCA RYR3 RYR3 tpcn2 tpcn2 PSEN1 PSEN1 CACNG2 CACNG2 GRIN2D GRIN2D MCOLN1 MCOLN1 P2RX4 P2RX4 ITPR3 ITPR3 CACNG6 CACNG6 CACNG7 CACNG7 PKD2L2 PKD2L2 CACNB1 CACNB1 TRPC4 TRPC4 SLC24A2 SLC24A2 MCOLN2 MCOLN2 Trpm5 Trpm5 MARCKSL1 MARCKSL1 CACNG8 CACNG8 G1KXM7_ANOCA G1KXM7_ANOCA G1KXS1_ANOCA G1KXS1_ANOCA LOC103282539 LOC103282539 H9GUY3_ANOCA H9GUY3_ANOCA LOC100559498 LOC100559498 H9GVG2_ANOCA H9GVG2_ANOCA CACFD1 CACFD1 CACNB3 CACNB3 GRIN2C GRIN2C
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G1K855_ANOCAVGCC_alpha2 domain-containing protein. (273 aa)
LOC100555851Ion_trans domain-containing protein. (483 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2415 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (308 aa)
CACNG1Calcium voltage-gated channel auxiliary subunit gamma 1. (227 aa)
GOLM1Golgi membrane protein 1. (427 aa)
LOC100555312Ion_trans domain-containing protein. (401 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (860 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (688 aa)
trpv5ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (726 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (684 aa)
CATSPER3Cation channel sperm associated 3. (368 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3. (324 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1041 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (226 aa)
Ryr1RIH_assoc domain-containing protein. (1224 aa)
H9G6F5_ANOCAUncharacterized protein. (664 aa)
H9G738_ANOCARYDR_ITPR domain-containing protein. (381 aa)
Ryr2Uncharacterized protein. (1021 aa)
G1KC21_ANOCAUncharacterized protein. (824 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1856 aa)
TMC2Transmembrane channel-like protein. (864 aa)
CATSPER4Cation channel sperm associated 4. (408 aa)
Cacna1aIon_trans domain-containing protein. (204 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (511 aa)
TPCN1Two pore segment channel 1. (806 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2312 aa)
SLC24A3Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (643 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2022 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (645 aa)
GPM6AGlycoprotein M6A. (280 aa)
LOC100566721Ion_trans domain-containing protein. (336 aa)
Pkd1Uncharacterized protein. (816 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (694 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2127 aa)
ORAI3ORAI calcium release-activated calcium modulator 2. (285 aa)
PKD1L3Uncharacterized protein. (1273 aa)
CALHM1Calcium homeostasis modulator 1. (336 aa)
CACHD1Cache domain containing 1. (1285 aa)
LOC100566195ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (733 aa)
LOC100552814Ion_trans domain-containing protein. (739 aa)
Catsper1Ion_trans domain-containing protein. (360 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1415 aa)
pkd1l2Uncharacterized protein. (2464 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (563 aa)
H9GEX9_ANOCAUncharacterized protein. (3670 aa)
TMEM37Transmembrane protein 37. (197 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1843 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1103 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2695 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1500 aa)
ANXA6Annexin. (693 aa)
cacna2d4VWFA domain-containing protein. (501 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1092 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (271 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1136 aa)
G1KLC7_ANOCACa_chan_IQ domain-containing protein. (872 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1098 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2188 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2065 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
LOC100560693Uncharacterized protein. (362 aa)
cacnb4SH3 domain-containing protein. (502 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (938 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (873 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (890 aa)
MCOLN3Mucolipin 3. (553 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1159 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1113 aa)
TMCO1Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2073 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (988 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1. (439 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (437 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1188 aa)
STIM2Stromal interaction molecule 2. (689 aa)
PKDREJPolycystin family receptor for egg jelly. (2088 aa)
H9GMB4_ANOCAIon_trans domain-containing protein. (182 aa)
RYR3Ryanodine receptor 3. (4700 aa)
tpcn2Uncharacterized protein. (709 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1252 aa)
MCOLN1Mucolipin 1. (572 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (393 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2659 aa)
CACNG6Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (259 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (281 aa)
PKD2L2Polycystin 2 like 2, transient receptor potential cation channel. (632 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (620 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (976 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (643 aa)
MCOLN2Mucolipin 2. (544 aa)
Trpm5LSDAT_euk domain-containing protein. (375 aa)
MARCKSL1MARCKS like 1. (279 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (368 aa)
G1KXM7_ANOCAUncharacterized protein. (666 aa)
G1KXS1_ANOCAIon_trans domain-containing protein. (785 aa)
LOC103282539Uncharacterized protein. (227 aa)
H9GUY3_ANOCAUncharacterized protein. (603 aa)
LOC100559498Uncharacterized protein. (756 aa)
H9GVG2_ANOCAUncharacterized protein. (589 aa)
CACFD1Calcium channel flower domain containing 1. (132 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (561 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1387 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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