17 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADAM10	ADAM metallopeptidase domain 10. (750 aa)
	DAG1	Dystroglycan 1. (888 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (454 aa)
	BACE2	Beta-secretase 2; Belongs to the peptidase A1 family. (513 aa)
	SPPL2A	Signal peptide peptidase like 2A. (552 aa)
	ADAM19	ADAM metallopeptidase domain 19. (911 aa)
	ADAM17	ADAM metallopeptidase domain 17. (835 aa)
	BACE1	Beta-secretase 1; Belongs to the peptidase A1 family. (318 aa)
	LRIG2	Leucine rich repeats and immunoglobulin like domains 2. (1053 aa)
	H9GQ91_ANOCA	Uncharacterized protein. (134 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (568 aa)
	LOC100553635	ZnMc domain-containing protein. (256 aa)
	LOC103278953	Peptidase S72 domain-containing protein. (1278 aa)
	psenen	Uncharacterized protein. (101 aa)
	ncstn	Ncstrn_small domain-containing protein. (340 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
	LOC100553835	ZnMc domain-containing protein. (265 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	H9GQ91_ANOCA	ENSACAP00000014756	ENSACAP00000018051	ADAM metallopeptidase domain 10.	Uncharacterized protein.	0.493
ADAM10	PSEN1	ENSACAP00000014756	ENSACAP00000015950	ADAM metallopeptidase domain 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.534
ADAM10	PSEN2	ENSACAP00000014756	ENSACAP00000006363	ADAM metallopeptidase domain 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.479
ADAM10	ncstn	ENSACAP00000014756	ENSACAP00000015968	ADAM metallopeptidase domain 10.	Ncstrn_small domain-containing protein.	0.493
ADAM10	psenen	ENSACAP00000014756	ENSACAP00000016385	ADAM metallopeptidase domain 10.	Uncharacterized protein.	0.574
ADAM17	BACE1	ENSACAP00000001499	ENSACAP00000001380	ADAM metallopeptidase domain 17.	Beta-secretase 1; Belongs to the peptidase A1 family.	0.478
ADAM17	H9GQ91_ANOCA	ENSACAP00000001499	ENSACAP00000018051	ADAM metallopeptidase domain 17.	Uncharacterized protein.	0.407
ADAM17	ncstn	ENSACAP00000001499	ENSACAP00000015968	ADAM metallopeptidase domain 17.	Ncstrn_small domain-containing protein.	0.504
ADAM17	psenen	ENSACAP00000001499	ENSACAP00000016385	ADAM metallopeptidase domain 17.	Uncharacterized protein.	0.458
BACE1	ADAM17	ENSACAP00000001380	ENSACAP00000001499	Beta-secretase 1; Belongs to the peptidase A1 family.	ADAM metallopeptidase domain 17.	0.478
BACE1	ncstn	ENSACAP00000001380	ENSACAP00000015968	Beta-secretase 1; Belongs to the peptidase A1 family.	Ncstrn_small domain-containing protein.	0.552
H9GQ91_ANOCA	ADAM10	ENSACAP00000018051	ENSACAP00000014756	Uncharacterized protein.	ADAM metallopeptidase domain 10.	0.493
H9GQ91_ANOCA	ADAM17	ENSACAP00000018051	ENSACAP00000001499	Uncharacterized protein.	ADAM metallopeptidase domain 17.	0.407
H9GQ91_ANOCA	PSEN1	ENSACAP00000018051	ENSACAP00000015950	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.954
H9GQ91_ANOCA	PSEN2	ENSACAP00000018051	ENSACAP00000006363	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.954
H9GQ91_ANOCA	ncstn	ENSACAP00000018051	ENSACAP00000015968	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.940
H9GQ91_ANOCA	psenen	ENSACAP00000018051	ENSACAP00000016385	Uncharacterized protein.	Uncharacterized protein.	0.962
LOC100553635	LOC100553835	ENSACAP00000018804	ENSACAP00000012383	ZnMc domain-containing protein.	ZnMc domain-containing protein.	0.903
LOC100553835	LOC100553635	ENSACAP00000012383	ENSACAP00000018804	ZnMc domain-containing protein.	ZnMc domain-containing protein.	0.903
PSEN1	ADAM10	ENSACAP00000015950	ENSACAP00000014756	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	ADAM metallopeptidase domain 10.	0.534