103 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	s1pr5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	LOC103278186	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
	H9GD08_ANOCA	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (473 aa)
	H9GD36_ANOCA	G_PROTEIN_RECEP_F1_2 domain-containing protein. (694 aa)
	RAMP3	Receptor activity modifying protein 3. (147 aa)
	MC4R	Melanocortin 4 receptor. (312 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
	ADGRB3	Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1267 aa)
	Adgrb2	Uncharacterized protein. (253 aa)
	ADGRG6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1201 aa)
	PTGIR	Prostaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (292 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	LOC100563268	Uncharacterized protein. (382 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (172 aa)
	GPR119	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (330 aa)
	adgrf3	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (861 aa)
	H9GF10_ANOCA	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (391 aa)
	TMEM116	Transmembrane protein 116. (327 aa)
	Gpr144	Uncharacterized protein. (92 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	LOC100567205	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	GPR68	G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (433 aa)
	ADRB1	Adrenoceptor beta 1. (432 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1122 aa)
	PTGER4	Prostaglandin E receptor 4. (161 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1227 aa)
	LOC103282163	Uncharacterized protein. (370 aa)
	GPR161	G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	G1KKH9_ANOCA	AC_N domain-containing protein. (356 aa)
	ADGRE5	Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (759 aa)
	DRD5	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	adcy5	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (794 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1483 aa)
	ghrh	GLUCAGON domain-containing protein. (170 aa)
	H9GIH8_ANOCA	G_PROTEIN_RECEP_F2_3 domain-containing protein. (885 aa)
	ADGRG2	Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. (938 aa)
	MC2R	Melanocortin 2 receptor. (318 aa)
	LOC103278676	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (684 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
	GPR65	G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1301 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
	RAMP2	Receptor activity modifying protein 2. (119 aa)
	CNR1	Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family. (473 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (453 aa)
	ADGRG1	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (675 aa)
	ADRB2	Adrenoceptor beta 2. (417 aa)
	ADRA2A	Adrenoceptor alpha 2A. (451 aa)
	RAMP1	Receptor activity modifying protein 1. (143 aa)
	MC3R	Melanocortin 3 receptor. (295 aa)
	GPHB5	Glycoprotein hormone subunit beta 5. (131 aa)
	adgrb1	G_PROTEIN_RECEP_F2_3 domain-containing protein. (850 aa)
	Adgrb1	G_PROTEIN_RECEP_F2_4 domain-containing protein. (645 aa)
	G1KSH8_ANOCA	G_PROTEIN_RECEP_F1_2 domain-containing protein. (228 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1604 aa)
	S1PR3	Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	RXFP1	Relaxin family peptide receptor 1. (761 aa)
	LOC100566713	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (435 aa)
	G1KSU8_ANOCA	Uncharacterized protein. (105 aa)
	H9GNL1_ANOCA	G_PROTEIN_RECEP_F1_2 domain-containing protein. (328 aa)
	PTGER1	Prostaglandin E receptor 1. (358 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (704 aa)
	S1PR4	Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (388 aa)
	GPR26	G protein-coupled receptor 26. (354 aa)
	H9GPF8_ANOCA	ANK_REP_REGION domain-containing protein. (260 aa)
	PLN	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
	GPR3	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (296 aa)
	PTHLH	Parathyroid hormone like hormone. (176 aa)
	gpa2	Putative glycoprotein hormone-alpha2. (61 aa)
	LOC103282528	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (267 aa)
	G1KWL3_ANOCA	Uncharacterized protein. (98 aa)
	akap13	Uncharacterized protein. (383 aa)
	ADCY3	Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (734 aa)
	GPR6	G protein-coupled receptor 6; Belongs to the G-protein coupled receptor 1 family. (327 aa)
	LOC100552643	G_PROTEIN_RECEP_F1_2 domain-containing protein. (241 aa)
	PTGER2	Prostaglandin E receptor 2. (304 aa)
	GALR1	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	LOC103278097	Uncharacterized protein. (382 aa)
	ADRA1D	Adrenoceptor alpha 1D; Belongs to the G-protein coupled receptor 1 family. (512 aa)
	LOC100554073	Uncharacterized protein. (251 aa)
	adrb3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (479 aa)
	gnas	Uncharacterized protein. (379 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	CALCRL	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (490 aa)
	ucn3	CRF domain-containing protein. (154 aa)
	S1PR1	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (546 aa)
	GPR12	G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	ADORA2A	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (393 aa)
	LOC103280671	G_PROTEIN_RECEP_F1_2 domain-containing protein. (336 aa)
	s1pr2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	LPAR2	Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	CNR2	Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (313 aa)
	VIP	Vasoactive intestinal peptide. (201 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (435 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (817 aa)
	LOC100555911	G_PROTEIN_RECEP_F1_2 domain-containing protein. (436 aa)
	ADGRL4	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (778 aa)
	ADGRL2	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1415 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSACAP00000007882	ENSACAP00000009989	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.456
ADCY1	ADCY3	ENSACAP00000007882	ENSACAP00000019460	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.578
ADCY1	ADCY4	ENSACAP00000007882	ENSACAP00000009399	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.463
ADCY1	ADCY6	ENSACAP00000007882	ENSACAP00000008442	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.442
ADCY1	ADCY7	ENSACAP00000007882	ENSACAP00000013999	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.469
ADCY1	ADCY8	ENSACAP00000007882	ENSACAP00000010472	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.955
ADCY1	ADCY9	ENSACAP00000007882	ENSACAP00000016127	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.668
ADCY1	ADRA2A	ENSACAP00000007882	ENSACAP00000015578	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adrenoceptor alpha 2A.	0.457
ADCY1	G1KKH9_ANOCA	ENSACAP00000007882	ENSACAP00000010568	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AC_N domain-containing protein.	0.416
ADCY1	LOC100555911	ENSACAP00000007882	ENSACAP00000006170	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.457
ADCY1	LOC100563268	ENSACAP00000007882	ENSACAP00000008459	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.960
ADCY1	LOC103278097	ENSACAP00000007882	ENSACAP00000023226	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.960
ADCY1	RAPGEF4	ENSACAP00000007882	ENSACAP00000006135	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Rap guanine nucleotide exchange factor 4.	0.914
ADCY1	adcy5	ENSACAP00000007882	ENSACAP00000010795	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.436
ADCY1	gnas	ENSACAP00000007882	ENSACAP00000000732	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.960
ADCY2	ADCY1	ENSACAP00000009989	ENSACAP00000007882	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.456
ADCY2	ADCY3	ENSACAP00000009989	ENSACAP00000019460	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.441
ADCY2	ADCY6	ENSACAP00000009989	ENSACAP00000008442	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.582
ADCY2	ADCY8	ENSACAP00000009989	ENSACAP00000010472	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.454
ADCY2	ADCY9	ENSACAP00000009989	ENSACAP00000016127	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.574