(58 nodes) Dendrite development network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H9GTM6_ANOCA	Uncharacterized protein. (980 aa)
	H9GHS1_ANOCA	KAP NTPase domain-containing protein. (549 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (1873 aa)
	MAP6	Microtubule associated protein 6. (441 aa)
	CDC42	Uncharacterized protein. (80 aa)
	MECP2	Methyl-CpG binding protein 2. (517 aa)
	PAK3	Non-specific serine/threonine protein kinase. (557 aa)
	DCX	Doublecortin. (265 aa)
	TMEM106B	Transmembrane protein 106B. (271 aa)
	TRAPPC4	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (219 aa)
	APP	Amyloid beta precursor protein. (776 aa)
	scarf1	EGF-like domain-containing protein. (463 aa)
	MCF2	MCF.2 cell line derived transforming sequence. (1091 aa)
	LOC100566319	Uncharacterized protein. (254 aa)
	BAIAP2	BAI1 associated protein 2. (530 aa)
	PRMT3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (526 aa)
	NTN5	Netrin 5. (579 aa)
	SULT4A1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (284 aa)
	PAK2	Non-specific serine/threonine protein kinase. (527 aa)
	FARP1	FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1038 aa)
	NTN1	Netrin 1. (654 aa)
	ABI1	Abl interactor 1. (447 aa)
	H9GQX5_ANOCA	Uncharacterized protein. (56 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1184 aa)
	LOC103280514	SH3 domain-containing protein. (95 aa)
	LOC100554656	CRIB domain-containing protein. (101 aa)
	MAP1A	Microtubule associated protein 1A. (2651 aa)
	PTN	Pleiotrophin. (187 aa)
	MAP2	Microtubule-associated protein. (1785 aa)
	KLHL4	Kelch like family member 4. (717 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1092 aa)
	NCK2	Cytoplasmic protein. (380 aa)
	bbs1	BBS1 domain-containing protein. (569 aa)
	MAP1B	Microtubule associated protein 1B. (2387 aa)
	KLF7	Kruppel like factor 7. (330 aa)
	EPHB1	EPH receptor B1. (1008 aa)
	NFATC4	Nuclear factor of activated T cells 4. (839 aa)
	LOC100558640	Uncharacterized protein. (697 aa)
	CRK	CRK proto-oncogene, adaptor protein. (228 aa)
	EPHB6	EPH receptor B6. (737 aa)
	EPHB3	EPH receptor B3. (987 aa)
	KLHL5	Kelch like family member 5. (756 aa)
	RELN	Reelin. (3312 aa)
	BBS4	Bardet-Biedl syndrome 4. (525 aa)
	LAMC2	Laminin subunit gamma 2. (1173 aa)
	KLHL1	Kelch like family member 1. (750 aa)
	PHACTR1	Phosphatase and actin regulator. (647 aa)
	SDC2	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (205 aa)
	G1KCP9_ANOCA	Protein kinase domain-containing protein. (368 aa)
	NKPD1	NTPase KAP family P-loop domain containing 1. (636 aa)
	DOCK10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2180 aa)
	DTNBP1	Dystrobrevin binding protein 1. (344 aa)
	GRIP1	Glutamate receptor interacting protein 1. (989 aa)
	KIDINS220	Kinase D interacting substrate 220. (1780 aa)
	pak1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (475 aa)
	ABITRAM	Actin binding transcription modulator. (181 aa)
	NTN3	Netrin 3. (647 aa)
	BTBD3	BTB domain containing 3. (461 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	BAIAP2	ENSACAP00000018039	ENSACAP00000015232	Abl interactor 1.	BAI1 associated protein 2.	0.923
ABI1	CDC42	ENSACAP00000018039	ENSACAP00000012248	Abl interactor 1.	Uncharacterized protein.	0.679
ABI1	CRK	ENSACAP00000018039	ENSACAP00000008212	Abl interactor 1.	CRK proto-oncogene, adaptor protein.	0.672
ABI1	LOC100566319	ENSACAP00000018039	ENSACAP00000014632	Abl interactor 1.	Uncharacterized protein.	0.576
ABI1	LOC103280514	ENSACAP00000018039	ENSACAP00000020306	Abl interactor 1.	SH3 domain-containing protein.	0.576
ABI1	NCK2	ENSACAP00000018039	ENSACAP00000010275	Abl interactor 1.	Cytoplasmic protein.	0.824
ABI1	PAK2	ENSACAP00000018039	ENSACAP00000015993	Abl interactor 1.	Non-specific serine/threonine protein kinase.	0.453
ABI1	SHANK3	ENSACAP00000018039	ENSACAP00000018540	Abl interactor 1.	SH3 and multiple ankyrin repeat domains 3.	0.501
APP	MAP2	ENSACAP00000014509	ENSACAP00000010845	Amyloid beta precursor protein.	Microtubule-associated protein.	0.521
APP	RELN	ENSACAP00000014509	ENSACAP00000006746	Amyloid beta precursor protein.	Reelin.	0.437
BAIAP2	ABI1	ENSACAP00000015232	ENSACAP00000018039	BAI1 associated protein 2.	Abl interactor 1.	0.923
BAIAP2	CDC42	ENSACAP00000015232	ENSACAP00000012248	BAI1 associated protein 2.	Uncharacterized protein.	0.969
BAIAP2	CRK	ENSACAP00000015232	ENSACAP00000008212	BAI1 associated protein 2.	CRK proto-oncogene, adaptor protein.	0.609
BAIAP2	LOC100566319	ENSACAP00000015232	ENSACAP00000014632	BAI1 associated protein 2.	Uncharacterized protein.	0.475
BAIAP2	LOC103280514	ENSACAP00000015232	ENSACAP00000020306	BAI1 associated protein 2.	SH3 domain-containing protein.	0.475
BAIAP2	NCK2	ENSACAP00000015232	ENSACAP00000010275	BAI1 associated protein 2.	Cytoplasmic protein.	0.817
BAIAP2	SHANK1	ENSACAP00000015232	ENSACAP00000011965	BAI1 associated protein 2.	SH3 and multiple ankyrin repeat domains 1.	0.442
BAIAP2	SHANK3	ENSACAP00000015232	ENSACAP00000018540	BAI1 associated protein 2.	SH3 and multiple ankyrin repeat domains 3.	0.645
BBS4	KLHL1	ENSACAP00000006722	ENSACAP00000004953	Bardet-Biedl syndrome 4.	Kelch like family member 1.	0.583
BBS4	KLHL4	ENSACAP00000006722	ENSACAP00000011273	Bardet-Biedl syndrome 4.	Kelch like family member 4.	0.583