STRINGSTRING
RPS6KA5 RPS6KA5 CAMK1 CAMK1 LOC100556560 LOC100556560 DYRK4 DYRK4 LOC100564355 LOC100564355 MAPKAPK5 MAPKAPK5 BRSK2 BRSK2 TGFBR1 TGFBR1 H9GEX9_ANOCA H9GEX9_ANOCA PNCK PNCK DYRK1A DYRK1A MAST1 MAST1 CAMK1D CAMK1D PRKCD PRKCD MYO3A MYO3A CSNK2A2 CSNK2A2 CAMKV CAMKV RPS6KB2 RPS6KB2 csnk1e csnk1e LRRK2 LRRK2 ROCK1 ROCK1 MASTL MASTL IL24 IL24 MAP3K13 MAP3K13 ILK ILK MAPKAPK2 MAPKAPK2 DYRK3 DYRK3 MAPK7 MAPK7 STK32C STK32C ULK1 ULK1 CAMK4 CAMK4 MAPKAPK3 MAPKAPK3 PDK3 PDK3 SMTNL1 SMTNL1 Pkd1 Pkd1 CSNK1G1 CSNK1G1 LATS1 LATS1 PRKAA2 PRKAA2 AKT3 AKT3 LOC103282236 LOC103282236 prkch prkch prkx prkx LOC100561800 LOC100561800 LOC100563653 LOC100563653 atm atm prkcq prkcq ATR ATR AURKB AURKB TTBK1 TTBK1 G1KCP9_ANOCA G1KCP9_ANOCA LOC100566597 LOC100566597 VRK2 VRK2 PRKCE PRKCE Tssk4 Tssk4 DYRK2 DYRK2 GSK3B GSK3B PDPK1 PDPK1 TBK1 TBK1 gsk3a gsk3a CSNK1G3 CSNK1G3 HIPK3 HIPK3 AKT2 AKT2 LOC100556408 LOC100556408 TNKS TNKS LATS2 LATS2 CSNK1D CSNK1D HIPK1 HIPK1 SGK2 SGK2 EIF2AK3 EIF2AK3 H9G626_ANOCA H9G626_ANOCA MAPK12 MAPK12 mknk1 mknk1 PKN2 PKN2 CDC7 CDC7 MAPK1 MAPK1 PRKCA PRKCA SMG1 SMG1 NTRK2 NTRK2 MAP3K12 MAP3K12 SYK SYK GAS6 GAS6 ULK2 ULK2 LOC100559765 LOC100559765 MTOR MTOR MKNK2 MKNK2 DGKQ DGKQ ROCK2 ROCK2 NLK NLK CSNK1A1 CSNK1A1 RPS6KA4 RPS6KA4 TTBK2 TTBK2 MAST2 MAST2 AURKA AURKA PRKCI PRKCI PBK PBK MAST4 MAST4 PAK2 PAK2 BAK1 BAK1 PRKCG PRKCG SGK3 SGK3 TLK1 TLK1 rps6ka1 rps6ka1 STK38 STK38 MAPK9 MAPK9 DYRK1B DYRK1B TLK2 TLK2 MYO3B MYO3B PKN1 PKN1 MAPK13 MAPK13 kiaa1549 kiaa1549 BRSK1 BRSK1 LOC100555783 LOC100555783 H9GTZ6_ANOCA H9GTZ6_ANOCA H9GTR0_ANOCA H9GTR0_ANOCA LOC100562662 LOC100562662 H9GSU7_ANOCA H9GSU7_ANOCA MAST3 MAST3 LOC100560018 LOC100560018 CDK1 CDK1 HIPK4 HIPK4 G1KVX5_ANOCA G1KVX5_ANOCA LOC100555978 LOC100555978 RIPK1 RIPK1 BCL2 BCL2 BAX BAX TTK TTK clspn clspn TOP1 TOP1 LOC100567618 LOC100567618 SGK1 SGK1 PRKAA1 PRKAA1 DCLK3 DCLK3 RICTOR RICTOR PIKFYVE PIKFYVE RPS6KA2 RPS6KA2 vrk3 vrk3 MAPK3 MAPK3 H9GLN0_ANOCA H9GLN0_ANOCA NEK7 NEK7 STK32A STK32A rps6ka6 rps6ka6 TGFBR2 TGFBR2 VRK1 VRK1 LOC103282869 LOC103282869 IKBKE IKBKE rps6kb1 rps6kb1 LOC100553094 LOC100553094 RPS6KA3 RPS6KA3 IKBKB IKBKB morc3 morc3 STK38L STK38L H9GIS8_ANOCA H9GIS8_ANOCA CHUK CHUK PLK1 PLK1 PRKDC PRKDC AKT1 AKT1 csnk2a1 csnk2a1 PDGFB PDGFB LOC100554122-2 LOC100554122-2 LOC103282196 LOC103282196 H9GVG2_ANOCA H9GVG2_ANOCA LOC103282539 LOC103282539
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KA5Ribosomal protein S6 kinase. (838 aa)
CAMK1Calcium/calmodulin dependent protein kinase I. (346 aa)
LOC100556560Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (481 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (387 aa)
LOC100564355Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (307 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
BRSK2BR serine/threonine kinase 2. (620 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
H9GEX9_ANOCAUncharacterized protein. (3670 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase. (334 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (753 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1517 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (368 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1771 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (317 aa)
CAMKVCaM kinase like vesicle associated. (478 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (528 aa)
csnk1eProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
LRRK2Leucine rich repeat kinase 2. (2540 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1357 aa)
MASTLMicrotubule associated serine/threonine kinase like. (847 aa)
IL24Interleukin 24. (178 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (943 aa)
ILKIntegrin linked kinase. (321 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (398 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (516 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (801 aa)
STK32CSerine/threonine kinase 32C. (379 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1031 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (415 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
PDK3Protein-serine/threonine kinase. (413 aa)
SMTNL1Smoothelin like 1. (440 aa)
Pkd1Uncharacterized protein. (816 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (458 aa)
LATS1Large tumor suppressor kinase 1. (1126 aa)
PRKAA2Non-specific serine/threonine protein kinase. (565 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC103282236Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (214 aa)
prkchProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (579 aa)
prkxUncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
LOC100561800Protein kinase domain-containing protein. (252 aa)
LOC100563653Protein kinase domain-containing protein. (314 aa)
atmUncharacterized protein; Belongs to the PI3/PI4-kinase family. (423 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2649 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (366 aa)
TTBK1Tau tubulin kinase 1. (1251 aa)
G1KCP9_ANOCAProtein kinase domain-containing protein. (368 aa)
LOC100566597Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
VRK2VRK serine/threonine kinase 2. (277 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (740 aa)
Tssk4Protein kinase domain-containing protein. (219 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (526 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (546 aa)
TBK1TANK binding kinase 1. (729 aa)
gsk3aProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (448 aa)
HIPK3Homeodomain interacting protein kinase 3. (1189 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC100556408FAT domain-containing protein. (2448 aa)
TNKSPoly [ADP-ribose] polymerase. (1286 aa)
LATS2Large tumor suppressor kinase 2. (1095 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (417 aa)
HIPK1Homeodomain interacting protein kinase 1. (1417 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (411 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1026 aa)
H9G626_ANOCAPhorbol-ester/DAG-type domain-containing protein. (291 aa)
MAPK12Mitogen-activated protein kinase. (361 aa)
mknk1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (466 aa)
PKN2Protein kinase N2. (982 aa)
CDC7Cell division cycle 7. (561 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (626 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3667 aa)
NTRK2Tyrosine-protein kinase receptor. (864 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (879 aa)
SYKTyrosine-protein kinase. (634 aa)
GAS6Growth arrest specific 6. (591 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1047 aa)
LOC100559765Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (230 aa)
MTORSerine/threonine-protein kinase TOR. (2314 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (395 aa)
DGKQDiacylglycerol kinase. (910 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1412 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
RPS6KA4Ribosomal protein S6 kinase. (766 aa)
TTBK2Tau tubulin kinase 2. (1234 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1390 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (456 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (693 aa)
PBKProtein kinase domain-containing protein. (329 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2610 aa)
PAK2Non-specific serine/threonine protein kinase. (527 aa)
BAK1BCL2 antagonist/killer 1. (214 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
TLK1Tousled like kinase 1. (719 aa)
rps6ka1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (468 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (690 aa)
TLK2Tousled like kinase 2. (750 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1123 aa)
PKN1Protein kinase N1. (943 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
kiaa1549KIAA1549. (1939 aa)
BRSK1BR serine/threonine kinase 1. (788 aa)
LOC100555783Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (271 aa)
H9GTZ6_ANOCAUncharacterized protein. (621 aa)
H9GTR0_ANOCAC2 domain-containing protein. (122 aa)
LOC100562662Protein kinase domain-containing protein. (278 aa)
H9GSU7_ANOCARRM domain-containing protein. (392 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1062 aa)
LOC100560018Protein kinase domain-containing protein. (173 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (313 aa)
HIPK4Homeodomain interacting protein kinase 4. (613 aa)
G1KVX5_ANOCAProtein kinase domain-containing protein. (147 aa)
LOC100555978Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (275 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (699 aa)
BCL2BCL2 apoptosis regulator. (170 aa)
BAXBCL2 associated X, apoptosis regulator. (207 aa)
TTKTTK protein kinase. (883 aa)
clspnUncharacterized protein. (283 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
LOC100567618Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
PRKAA1Non-specific serine/threonine protein kinase. (550 aa)
DCLK3Doublecortin like kinase 3. (652 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1731 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2125 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
vrk3Protein kinase domain-containing protein. (183 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
H9GLN0_ANOCAProtein kinase domain-containing protein. (213 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (306 aa)
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (396 aa)
rps6ka6Non-specific serine/threonine protein kinase. (700 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (417 aa)
LOC103282869Uncharacterized protein. (113 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (717 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa)
LOC100553094Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (349 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (711 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (761 aa)
morc3CW-type domain-containing protein. (932 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (464 aa)
H9GIS8_ANOCAAGC-kinase C-terminal domain-containing protein. (99 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (679 aa)
PLK1Polo like kinase 1. (416 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4100 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
csnk2a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (247 aa)
LOC100554122-2Uncharacterized protein. (221 aa)
LOC103282196Uncharacterized protein. (232 aa)
H9GVG2_ANOCAUncharacterized protein. (589 aa)
LOC103282539Uncharacterized protein. (227 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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