(120 nodes) Ubiquitin-like protein peptidase activity network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DESI2	Desumoylating isopeptidase 2. (193 aa)
	H9GUS8_ANOCA	DUSP domain-containing protein. (268 aa)
	LOC103278402	Uncharacterized LOC103278402. (152 aa)
	H9GU39_ANOCA	DUSP domain-containing protein. (260 aa)
	Prrt3	Uncharacterized protein. (602 aa)
	H9GTZ3_ANOCA	DUSP domain-containing protein. (258 aa)
	H9GTI6_ANOCA	DUSP domain-containing protein. (150 aa)
	LOC103282719	Uncharacterized protein. (542 aa)
	H9GT34_ANOCA	DUSP domain-containing protein. (256 aa)
	LOC103279137	DUSP domain-containing protein. (152 aa)
	G1KWL9_ANOCA	DUSP domain-containing protein. (156 aa)
	USP2	Ubiquitin carboxyl-terminal hydrolase. (596 aa)
	H9GS08_ANOCA	DUSP domain-containing protein. (258 aa)
	G1KVT8_ANOCA	DUSP domain-containing protein. (260 aa)
	H9GR29_ANOCA	RAMA domain-containing protein. (173 aa)
	Usp30	USP domain-containing protein; Belongs to the peptidase C19 family. (68 aa)
	LOC103280160	DUF862 domain-containing protein. (196 aa)
	usp9x	USP domain-containing protein; Belongs to the peptidase C19 family. (2553 aa)
	USP43	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (926 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (609 aa)
	TNFAIP3	TNF alpha induced protein 3. (829 aa)
	H9GNG7_ANOCA	MitMem_reg domain-containing protein. (229 aa)
	MINDY3	MINDY lysine 48 deubiquitinase 3. (445 aa)
	VCPIP1	Valosin containing protein interacting protein 1. (1216 aa)
	COPS5	COP9 signalosome subunit 5. (293 aa)
	usp36	Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1115 aa)
	USP3	Ubiquitin carboxyl-terminal hydrolase. (533 aa)
	usp32	Uncharacterized protein; Belongs to the peptidase C19 family. (1528 aa)
	MINDY2	MINDY lysine 48 deubiquitinase 2. (491 aa)
	USP31	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1374 aa)
	LOC100555575	Ubiquitin specific peptidase 10. (452 aa)
	ZRANB1	Zinc finger RANBP2-type containing 1. (708 aa)
	CYLD	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
	USP44	Ubiquitin carboxyl-terminal hydrolase. (712 aa)
	Zufsp	Uncharacterized protein. (201 aa)
	YOD1	YOD1 deubiquitinase. (310 aa)
	USP53	Ubiquitin specific peptidase 53. (1105 aa)
	USP19	Ubiquitin specific peptidase 19. (1376 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase. (777 aa)
	MINDY4B	MINDY family member 4B. (356 aa)
	OTUD5	OTU deubiquitinase 5. (346 aa)
	USP33	Ubiquitin carboxyl-terminal hydrolase. (897 aa)
	SENP1	SUMO specific peptidase 1. (629 aa)
	USP7	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1094 aa)
	USP46	Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (366 aa)
	H9GAN4_ANOCA	MINDY_DUB domain-containing protein. (299 aa)
	MINDY4	MINDY lysine 48 deubiquitinase 4. (752 aa)
	USP5	Ubiquitin carboxyl-terminal hydrolase. (832 aa)
	senp3	ULP_PROTEASE domain-containing protein. (567 aa)
	OTULINL	OTU deubiquitinase with linear linkage specificity like. (286 aa)
	MYSM1	Myb like, SWIRM and MPN domains 1. (820 aa)
	USPL1	Ubiquitin specific peptidase like 1. (1072 aa)
	USP11	Ubiquitin specific peptidase 11; Belongs to the peptidase C19 family. (911 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1376 aa)
	SENP6	SUMO specific peptidase 6. (1143 aa)
	DESI1	Desumoylating isopeptidase 1. (169 aa)
	USP13	Ubiquitin carboxyl-terminal hydrolase. (939 aa)
	USP21	Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (595 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1078 aa)
	USP50	Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (378 aa)
	PSMD7	Proteasome 26S subunit, non-ATPase 7. (365 aa)
	OTUD4	OTU deubiquitinase 4. (1124 aa)
	OTUD7B	OTU deubiquitinase 7B. (822 aa)
	OTUD6B	OTU domain containing 6B. (316 aa)
	USP12	Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family. (370 aa)
	OTUD7A	OTU deubiquitinase 7A. (933 aa)
	USP49	Ubiquitin carboxyl-terminal hydrolase. (696 aa)
	USP38	Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family. (1044 aa)
	USP34	Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3560 aa)
	LOC100564160	USP domain-containing protein; Belongs to the peptidase C19 family. (372 aa)
	USP37	Ubiquitin carboxyl-terminal hydrolase. (969 aa)
	UFSP2	UFM1 specific peptidase 2. (479 aa)
	UCHL3	Ubiquitin carboxyl-terminal hydrolase. (231 aa)
	LOC103281743	Uncharacterized protein; Belongs to the peptidase C19 family. (453 aa)
	STAMBP	STAM binding protein. (420 aa)
	USP16	Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (839 aa)
	USP22	Ubiquitin carboxyl-terminal hydrolase. (540 aa)
	CEP112	Centrosomal protein 112. (1004 aa)
	USP15	Ubiquitin specific peptidase 15; Belongs to the peptidase C19 family. (1041 aa)
	UFSP1	UFM1 specific peptidase 1 (inactive). (223 aa)
	USP48	Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (508 aa)
	ATG4B	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
	STAMBPL1	STAM binding protein like 1. (448 aa)
	BRCC3	BRCA1/BRCA2-containing complex subunit 3. (261 aa)
	OTULIN	OTU deubiquitinase with linear linkage specificity. (335 aa)
	USP24	Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2605 aa)
	OTUD1	OTU deubiquitinase 1. (368 aa)
	atxn3	Josephin domain-containing protein. (331 aa)
	Prrt4	Uncharacterized protein. (521 aa)
	COX20	Cytochrome c oxidase assembly factor COX20. (115 aa)
	usp10	USP domain-containing protein; Belongs to the peptidase C19 family. (334 aa)
	USP42	Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (1298 aa)
	OTUB1	Ubiquitin thioesterase. (273 aa)
	USP35	Ubiquitin carboxyl-terminal hydrolase. (781 aa)
	cops6	MitMem_reg domain-containing protein. (150 aa)
	BAP1	BRCA1 associated protein 1. (733 aa)
	usp18	USP domain-containing protein; Belongs to the peptidase C19 family. (387 aa)
	ATG4A	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (397 aa)
	UCHL1	Ubiquitin carboxyl-terminal hydrolase. (224 aa)
	JOSD2	Josephin domain containing 2. (188 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	SENP7	SUMO specific peptidase 7. (1043 aa)
	SENP8	SUMO peptidase family member, NEDD8 specific. (221 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (308 aa)
	COPS4	COP9 signalosome subunit 4. (194 aa)
	USP25	Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (791 aa)
	USP45	Ubiquitin carboxyl-terminal hydrolase. (813 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (330 aa)
	USP54	Ubiquitin specific peptidase 54. (1693 aa)
	USP40	Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1234 aa)
	USP20	Ubiquitin specific peptidase 20; Belongs to the peptidase C19 family. (751 aa)
	LOC103279578	USP domain-containing protein. (209 aa)
	USP28	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1130 aa)
	UCHL5	Ubiquitin carboxyl-terminal hydrolase. (331 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase. (495 aa)
	USP4	Ubiquitin carboxyl-terminal hydrolase. (961 aa)
	USP39	Ubiquitin specific peptidase 39. (456 aa)
	JOSD1	Josephin domain containing 1. (202 aa)
	SENP2	SUMO specific peptidase 2. (518 aa)
	SENP5	SUMO specific peptidase 5. (760 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAP1	BRCC3	ENSACAP00000012153	ENSACAP00000000405	BRCA1 associated protein 1.	BRCA1/BRCA2-containing complex subunit 3.	0.802
BAP1	COPS5	ENSACAP00000012153	ENSACAP00000016152	BRCA1 associated protein 1.	COP9 signalosome subunit 5.	0.661
BAP1	EIF3F	ENSACAP00000012153	ENSACAP00000010109	BRCA1 associated protein 1.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.585
BAP1	H9GNG7_ANOCA	ENSACAP00000012153	ENSACAP00000016388	BRCA1 associated protein 1.	MitMem_reg domain-containing protein.	0.536
BAP1	H9GR29_ANOCA	ENSACAP00000012153	ENSACAP00000018552	BRCA1 associated protein 1.	RAMA domain-containing protein.	0.736
BAP1	MYSM1	ENSACAP00000012153	ENSACAP00000005394	BRCA1 associated protein 1.	Myb like, SWIRM and MPN domains 1.	0.809
BAP1	PSMD14	ENSACAP00000012153	ENSACAP00000011690	BRCA1 associated protein 1.	Proteasome 26S subunit, non-ATPase 14.	0.973
BAP1	PSMD7	ENSACAP00000012153	ENSACAP00000003771	BRCA1 associated protein 1.	Proteasome 26S subunit, non-ATPase 7.	0.963
BAP1	STAMBP	ENSACAP00000012153	ENSACAP00000001747	BRCA1 associated protein 1.	STAM binding protein.	0.621
BAP1	STAMBPL1	ENSACAP00000012153	ENSACAP00000000645	BRCA1 associated protein 1.	STAM binding protein like 1.	0.621
BAP1	USP14	ENSACAP00000012153	ENSACAP00000008126	BRCA1 associated protein 1.	Ubiquitin carboxyl-terminal hydrolase.	0.931
BAP1	cops6	ENSACAP00000012153	ENSACAP00000012174	BRCA1 associated protein 1.	MitMem_reg domain-containing protein.	0.536
BRCC3	BAP1	ENSACAP00000000405	ENSACAP00000012153	BRCA1/BRCA2-containing complex subunit 3.	BRCA1 associated protein 1.	0.802
BRCC3	CEP112	ENSACAP00000000405	ENSACAP00000001404	BRCA1/BRCA2-containing complex subunit 3.	Centrosomal protein 112.	0.404
BRCC3	COPS4	ENSACAP00000000405	ENSACAP00000010485	BRCA1/BRCA2-containing complex subunit 3.	COP9 signalosome subunit 4.	0.746
BRCC3	EIF3H	ENSACAP00000000405	ENSACAP00000010921	BRCA1/BRCA2-containing complex subunit 3.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.786
BRCC3	PSMD7	ENSACAP00000000405	ENSACAP00000003771	BRCA1/BRCA2-containing complex subunit 3.	Proteasome 26S subunit, non-ATPase 7.	0.950
BRCC3	Prrt3	ENSACAP00000000405	ENSACAP00000020465	BRCA1/BRCA2-containing complex subunit 3.	Uncharacterized protein.	0.404
BRCC3	Prrt4	ENSACAP00000000405	ENSACAP00000022095	BRCA1/BRCA2-containing complex subunit 3.	Uncharacterized protein.	0.404
BRCC3	SENP8	ENSACAP00000000405	ENSACAP00000011282	BRCA1/BRCA2-containing complex subunit 3.	SUMO peptidase family member, NEDD8 specific.	0.483