(62 nodes) Actin filament-based movement network (Anolis carolinensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYO5C	Myosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1453 aa)
	LOC100566259	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (992 aa)
	WIPF3	WAS/WASL interacting protein family member 3. (523 aa)
	LOC103281985	TH1 domain-containing protein. (143 aa)
	WIPF2	WAS/WASL interacting protein family member 2. (440 aa)
	MYO7A	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2164 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (737 aa)
	LOC100564878	Uncharacterized protein; Belongs to the potassium channel family. (632 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (198 aa)
	SCN3B	Sodium voltage-gated channel beta subunit 3. (215 aa)
	MYO6	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1263 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CACNA1G	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2312 aa)
	kcne1	Uncharacterized protein. (127 aa)
	WIPF1	WAS/WASL interacting protein family member 1. (505 aa)
	FNBP1L	Formin binding protein 1 like. (615 aa)
	MYO7B	Myosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2205 aa)
	SCN1B	Sodium voltage-gated channel beta subunit 1. (221 aa)
	WAS	WASP actin nucleation promoting factor. (502 aa)
	MYO1B	Myosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1173 aa)
	LOC100563782	Uncharacterized protein. (728 aa)
	SCN2B	Sodium voltage-gated channel beta subunit 2. (216 aa)
	SCN4B	Sodium voltage-gated channel beta subunit 4. (115 aa)
	MYO1A	Myosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1073 aa)
	MYL6	Uncharacterized protein. (151 aa)
	SUN2	Sad1 and UNC84 domain containing 2. (716 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1357 aa)
	frmd1	FERM domain-containing protein. (604 aa)
	SNTA1	Syntrophin alpha 1. (592 aa)
	LOC103282691	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (231 aa)
	myo1h	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (323 aa)
	MYO19	Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (855 aa)
	LOC103282001	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (785 aa)
	LOC100555044	Nucleoporin_N domain-containing protein. (631 aa)
	SHTN1	Shootin 1. (650 aa)
	H9GHE9_ANOCA	TH1 domain-containing protein. (193 aa)
	MYO5A	Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1823 aa)
	LOC100567364	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1072 aa)
	PKP2	Plakophilin 2. (799 aa)
	KCNE5	Potassium voltage-gated channel subfamily E regulatory subunit 5. (93 aa)
	MYO1E	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1079 aa)
	L7N022_ANOCA	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (303 aa)
	MYO1D	Myosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (711 aa)
	LOC100567040	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (670 aa)
	KCNJ8	Potassium voltage-gated channel subfamily J member 8. (421 aa)
	ABCC9	ATP binding cassette subfamily C member 9. (1296 aa)
	EPDR1	Ependymin related 1. (179 aa)
	WASF2	WASP family member 2. (495 aa)
	FRMD6	FERM domain containing 6. (622 aa)
	LOC100553759	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1104 aa)
	H9GQ14_ANOCA	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (294 aa)
	H9GQI4_ANOCA	Nucleoporin_C domain-containing protein. (498 aa)
	KCNJ5	Potassium voltage-gated channel subfamily J member 5. (455 aa)
	H9GTF9_ANOCA	MyTH4 domain-containing protein. (680 aa)
	LIMCH1	LIM and calponin homology domains 1. (1043 aa)
	H9GTP0_ANOCA	Nucleoporin_N domain-containing protein. (572 aa)
	myo9b	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (800 aa)
	MYL6B	Uncharacterized protein. (203 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (116 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (707 aa)
	WASL	WASP like actin nucleation promoting factor. (513 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC9	KCNJ5	ENSACAP00000016958	ENSACAP00000019964	ATP binding cassette subfamily C member 9.	Potassium voltage-gated channel subfamily J member 5.	0.471
ABCC9	KCNJ8	ENSACAP00000016958	ENSACAP00000016855	ATP binding cassette subfamily C member 9.	Potassium voltage-gated channel subfamily J member 8.	0.976
CACNA1G	SCN1B	ENSACAP00000004908	ENSACAP00000005635	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Sodium voltage-gated channel beta subunit 1.	0.587
CACNA1G	SCN3B	ENSACAP00000004908	ENSACAP00000004672	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Sodium voltage-gated channel beta subunit 3.	0.584
FNBP1L	LOC100566259	ENSACAP00000005402	ENSACAP00000000689	Formin binding protein 1 like.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.659
FNBP1L	LOC100567040	ENSACAP00000005402	ENSACAP00000016697	Formin binding protein 1 like.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.659
FNBP1L	MYO1E	ENSACAP00000005402	ENSACAP00000015047	Formin binding protein 1 like.	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.659
FNBP1L	WAS	ENSACAP00000005402	ENSACAP00000006165	Formin binding protein 1 like.	WASP actin nucleation promoting factor.	0.935
FNBP1L	WASF2	ENSACAP00000005402	ENSACAP00000017556	Formin binding protein 1 like.	WASP family member 2.	0.488
FNBP1L	WASL	ENSACAP00000005402	ENSACAP00000022831	Formin binding protein 1 like.	WASP like actin nucleation promoting factor.	0.935
FNBP1L	WIPF1	ENSACAP00000005402	ENSACAP00000005306	Formin binding protein 1 like.	WAS/WASL interacting protein family member 1.	0.630
FNBP1L	WIPF2	ENSACAP00000005402	ENSACAP00000002419	Formin binding protein 1 like.	WAS/WASL interacting protein family member 2.	0.606
FNBP1L	WIPF3	ENSACAP00000005402	ENSACAP00000000760	Formin binding protein 1 like.	WAS/WASL interacting protein family member 3.	0.596
H9GHE9_ANOCA	H9GQ14_ANOCA	ENSACAP00000011077	ENSACAP00000017838	TH1 domain-containing protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.898
H9GHE9_ANOCA	L7N022_ANOCA	ENSACAP00000011077	ENSACAP00000015080	TH1 domain-containing protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.913
H9GHE9_ANOCA	LOC100567040	ENSACAP00000011077	ENSACAP00000016697	TH1 domain-containing protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.823
H9GHE9_ANOCA	LOC103282001	ENSACAP00000011077	ENSACAP00000009488	TH1 domain-containing protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.727
H9GHE9_ANOCA	LOC103282691	ENSACAP00000011077	ENSACAP00000008561	TH1 domain-containing protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.645
H9GHE9_ANOCA	MYO1E	ENSACAP00000011077	ENSACAP00000015047	TH1 domain-containing protein.	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.671
H9GHE9_ANOCA	MYO6	ENSACAP00000011077	ENSACAP00000004853	TH1 domain-containing protein.	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.400