STRINGSTRING
THRA THRA LOC100560601 LOC100560601 EDN2 EDN2 CCN2 CCN2 H9G4L9_ANOCA H9G4L9_ANOCA LOC100559751 LOC100559751 LOC100564288 LOC100564288 LOC100564784 LOC100564784 STK40 STK40 MMP14 MMP14 SLC7A11 SLC7A11 HPS1 HPS1 DAG1 DAG1 PHEX PHEX TAB1 TAB1 CCBE1 CCBE1 GATA6 GATA6 DLG5 DLG5 JMJD6 JMJD6 PKDCC PKDCC H9GEX9_ANOCA H9GEX9_ANOCA CREB1 CREB1 ZFPM2 ZFPM2 KDR KDR ESRP2 ESRP2 LOC100559698 LOC100559698 TCF21 TCF21 HOXA5 HOXA5 NKIRAS1 NKIRAS1 THRB THRB SPRY1 SPRY1 FGF2 FGF2 FGF8 FGF8 rc3h2 rc3h2 ITGB6 ITGB6 BAG6 BAG6 SEC24B SEC24B DNAAF1 DNAAF1 LOC100558604 LOC100558604 LOC100552212 LOC100552212 AIMP2 AIMP2 PHF14 PHF14 LOC100558405 LOC100558405 FGF1 FGF1 TGFBR2 TGFBR2 SAV1 SAV1 RDH10 RDH10 H9GL28_ANOCA H9GL28_ANOCA ADAMTSL2 ADAMTSL2 CTSH CTSH FGF7 FGF7 FLT4 FLT4 CCDC40 CCDC40 FNDC3B FNDC3B TIMELESS TIMELESS RXFP1 RXFP1 NKIRAS2 NKIRAS2 TTC25 TTC25 SP3 SP3 MYOCD MYOCD GLI3 GLI3 WNT2B WNT2B LOC100559158 LOC100559158 LOC103282347 LOC103282347 TGFB1 TGFB1 G1KWG1_ANOCA G1KWG1_ANOCA FGF18 FGF18 ATXN1L ATXN1L Numa1 Numa1 LOC103282539 LOC103282539 H9GVG2_ANOCA H9GVG2_ANOCA HSPB11 HSPB11 LOC103278953 LOC103278953 EP300 EP300 PTK7 PTK7 BMPR2 BMPR2 SRF SRF ELK1 ELK1 CTNNB1 CTNNB1 TMEM38B TMEM38B EPAS1 EPAS1 FBXW9 FBXW9 HHIP HHIP H9G7A9_ANOCA H9G7A9_ANOCA FBXW7 FBXW7 LOC100555943 LOC100555943 HOPX HOPX LOC100567564 LOC100567564 itga3 itga3 hsd11b1 hsd11b1 GLI1 GLI1 Pkd1 Pkd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THRAThyroid hormone receptor alpha. (371 aa)
LOC100560601Insulin like growth factor binding protein 5. (146 aa)
EDN2Endothelin 2. (67 aa)
CCN2Cellular communication network factor 2. (350 aa)
H9G4L9_ANOCAPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (280 aa)
LOC100559751Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (309 aa)
LOC100564288Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (309 aa)
LOC100564784PLAC domain-containing protein. (885 aa)
STK40Serine/threonine kinase 40. (441 aa)
MMP14Matrix metallopeptidase 14. (511 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (704 aa)
DAG1Dystroglycan 1. (888 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (751 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (535 aa)
CCBE1Collagen and calcium binding EGF domains 1. (381 aa)
GATA6GATA binding protein 6. (562 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1957 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (294 aa)
H9GEX9_ANOCAUncharacterized protein. (3670 aa)
CREB1cAMP responsive element binding protein 1. (349 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1149 aa)
KDRKinase insert domain receptor. (1357 aa)
ESRP2Epithelial splicing regulatory protein 2. (718 aa)
LOC100559698Uncharacterized protein. (604 aa)
TCF21Transcription factor 21. (178 aa)
HOXA5Homeobox A5. (305 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (191 aa)
THRBThyroid hormone receptor beta. (499 aa)
SPRY1Sprouty RTK signaling antagonist 1. (320 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
rc3h2Uncharacterized protein. (190 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
BAG6BCL2 associated athanogene 6. (1193 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1198 aa)
DNAAF1Dynein assembly factor 1, axonemal. (413 aa)
LOC100558604Uncharacterized protein. (507 aa)
LOC100552212PIP49_C domain-containing protein. (307 aa)
AIMP2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (369 aa)
PHF14PHD finger protein 14. (964 aa)
LOC100558405Uncharacterized protein. (474 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (570 aa)
SAV1Salvador family WW domain containing protein 1. (367 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
H9GL28_ANOCAUncharacterized protein. (835 aa)
ADAMTSL2ADAMTS like 2. (949 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (285 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1384 aa)
CCDC40Coiled-coil domain containing 40. (881 aa)
FNDC3BFibronectin type III domain containing 3B. (1213 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
RXFP1Relaxin family peptide receptor 1. (761 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (215 aa)
TTC25Tetratricopeptide repeat domain 25. (646 aa)
SP3Sp3 transcription factor. (786 aa)
MYOCDMyocardin. (956 aa)
GLI3GLI family zinc finger 3. (1489 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
LOC100559158Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
LOC103282347Integrin_alpha2 domain-containing protein. (329 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
G1KWG1_ANOCAIGFBP N-terminal domain-containing protein. (51 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
ATXN1LAtaxin 1 like. (620 aa)
Numa1Uncharacterized protein. (1009 aa)
LOC103282539Uncharacterized protein. (227 aa)
H9GVG2_ANOCAUncharacterized protein. (589 aa)
HSPB11Heat shock protein family B (small) member 11. (138 aa)
LOC103278953Peptidase S72 domain-containing protein. (1278 aa)
EP300E1A binding protein p300. (2484 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
SRFSerum response factor. (474 aa)
ELK1ETS transcription factor ELK1. (439 aa)
CTNNB1Catenin beta 1. (781 aa)
TMEM38BTransmembrane protein 38B. (290 aa)
EPAS1Endothelial PAS domain protein 1. (871 aa)
FBXW9F-box and WD repeat domain containing 9. (493 aa)
HHIPHedgehog interacting protein. (608 aa)
H9G7A9_ANOCAUncharacterized protein. (197 aa)
FBXW7F-box and WD repeat domain containing 7. (592 aa)
LOC100555943Uncharacterized protein. (290 aa)
HOPXHOP homeobox. (73 aa)
LOC100567564Uncharacterized protein. (189 aa)
itga3Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1053 aa)
hsd11b1Hydroxysteroid 11-beta dehydrogenase 1. (293 aa)
GLI1GLI family zinc finger 1. (1112 aa)
Pkd1Uncharacterized protein. (816 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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