(10 nodes) Regulation of complement activation network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4GB06_ANOCA	Uncharacterized protein. (101 aa)
	SUSD4	Sushi domain containing 4. (301 aa)
	vsig4	V-set and immunoglobulin domain containing 4. (415 aa)
	PHB	Prohibitin. (275 aa)
	C1QBP	Complement C1q binding protein. (284 aa)
	SERPING1	Serpin family G member 1; Belongs to the serpin family. (483 aa)
	LOC100564157	Prohibitin. (272 aa)
	H9GFU8_ANOCA	Uncharacterized protein. (504 aa)
	H9GK43_ANOCA	Uncharacterized protein. (1804 aa)
	H9GTG4_ANOCA	Uncharacterized protein. (394 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QBP	LOC100564157	ENSACAP00000007009	ENSACAP00000009184	Complement C1q binding protein.	Prohibitin.	0.686
C1QBP	PHB	ENSACAP00000007009	ENSACAP00000004698	Complement C1q binding protein.	Prohibitin.	0.686
C1QBP	SERPING1	ENSACAP00000007009	ENSACAP00000007015	Complement C1q binding protein.	Serpin family G member 1; Belongs to the serpin family.	0.643
LOC100564157	C1QBP	ENSACAP00000009184	ENSACAP00000007009	Prohibitin.	Complement C1q binding protein.	0.686
PHB	C1QBP	ENSACAP00000004698	ENSACAP00000007009	Prohibitin.	Complement C1q binding protein.	0.686
R4GB06_ANOCA	SERPING1	ENSACAP00000022471	ENSACAP00000007015	Uncharacterized protein.	Serpin family G member 1; Belongs to the serpin family.	0.461
SERPING1	C1QBP	ENSACAP00000007015	ENSACAP00000007009	Serpin family G member 1; Belongs to the serpin family.	Complement C1q binding protein.	0.643
SERPING1	R4GB06_ANOCA	ENSACAP00000007015	ENSACAP00000022471	Serpin family G member 1; Belongs to the serpin family.	Uncharacterized protein.	0.461