65 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NAXE	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (690 aa)
	SYK	Tyrosine-protein kinase. (634 aa)
	GPS2	G protein pathway suppressor 2. (136 aa)
	EPRS1	Glutamyl-prolyl-tRNA synthetase. (1524 aa)
	APOA4	Apolipoprotein A4. (369 aa)
	nfkbia	ANK_REP_REGION domain-containing protein. (310 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1041 aa)
	TNFSF11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)
	ARV1	ARV1 homolog, fatty acid homeostasis modulator. (234 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (252 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (580 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (698 aa)
	GALR1	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	TNFRSF11A	TNF receptor superfamily member 11a. (657 aa)
	C1QTNF1	C1q and TNF related 1. (272 aa)
	BMP6	Bone morphogenetic protein 6. (299 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (408 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (666 aa)
	LOC100555537	FAD_binding_7 domain-containing protein. (392 aa)
	PRELID1	PRELI domain containing 1. (216 aa)
	C1QTNF8	C1q and TNF related 8. (199 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LPCAT3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (476 aa)
	EEPD1	Endonuclease/exonuclease/phosphatase family domain containing 1. (556 aa)
	PLA2G6	Phospholipase A2 group VI. (663 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa)
	PTGES	Prostaglandin E synthase. (146 aa)
	LOC100567117	Uncharacterized protein. (270 aa)
	LOC100561467	Uncharacterized protein. (441 aa)
	LOC100567205	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	ACSL5	Acyl-CoA synthetase long chain family member 5. (696 aa)
	LOC100568171	Phospholipase A(2). (124 aa)
	DAB2	DAB adaptor protein 2. (638 aa)
	SIRT1	Sirtuin 1. (634 aa)
	POMC	Proopiomelanocortin. (240 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (157 aa)
	PLA2R1	Phospholipase A2 receptor 1. (1473 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (436 aa)
	SPP1	Secreted phosphoprotein 1. (289 aa)
	yjefn3	YjeF N-terminal domain-containing protein. (235 aa)
	PTCH1	Patched 1. (1047 aa)
	LOC100561963	Photolyase/cryptochrome alpha/beta domain-containing protein. (554 aa)
	Ldlrap1	PID domain-containing protein. (64 aa)
	PLTP	Phospholipid transfer protein. (489 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (292 aa)
	LAMTOR1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
	CRY2	Cryptochrome circadian regulator 2. (586 aa)
	SURF4	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (677 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (619 aa)
	TMF1	TATA element modulatory factor 1. (1098 aa)
	CRY1	Cryptochrome circadian regulator 1. (621 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (675 aa)
	ABCA12	ATP binding cassette subfamily A member 12. (2593 aa)
	PODNL1	Podocan like 1. (584 aa)
	ENPP7	Ectonucleotide pyrophosphatase/phosphodiesterase 7. (417 aa)
	C1QTNF6	C1q and TNF related 6. (261 aa)
	CRH	Corticotropin releasing hormone. (202 aa)
	itgb3	Integrin beta; Belongs to the integrin beta chain family. (585 aa)
	LOC100567765	Uncharacterized protein. (528 aa)
	TTC39B	Tetratricopeptide repeat domain 39B. (554 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (568 aa)
	apoe	Uncharacterized protein. (252 aa)
	PODN	Podocan. (597 aa)
	FASLG	Fas ligand; Belongs to the tumor necrosis factor family. (261 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA12	PCSK9	ENSACAP00000015245	ENSACAP00000000160	ATP binding cassette subfamily A member 12.	Proprotein convertase subtilisin/kexin type 9.	0.423
ABCA12	apoe	ENSACAP00000015245	ENSACAP00000018466	ATP binding cassette subfamily A member 12.	Uncharacterized protein.	0.489
ABCG1	ABCG5	ENSACAP00000003045	ENSACAP00000014992	ATP binding cassette subfamily G member 1.	ATP binding cassette subfamily G member 5.	0.797
ABCG1	NR1H2	ENSACAP00000003045	ENSACAP00000012374	ATP binding cassette subfamily G member 1.	Nuclear receptor subfamily 1 group H member 2.	0.423
ABCG1	apoe	ENSACAP00000003045	ENSACAP00000018466	ATP binding cassette subfamily G member 1.	Uncharacterized protein.	0.597
ABCG4	ABCG5	ENSACAP00000002376	ENSACAP00000014992	ATP binding cassette subfamily G member 4.	ATP binding cassette subfamily G member 5.	0.787
ABCG4	apoe	ENSACAP00000002376	ENSACAP00000018466	ATP binding cassette subfamily G member 4.	Uncharacterized protein.	0.597
ABCG5	ABCG1	ENSACAP00000014992	ENSACAP00000003045	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 1.	0.797
ABCG5	ABCG4	ENSACAP00000014992	ENSACAP00000002376	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 4.	0.787
ABCG5	ABCG8	ENSACAP00000014992	ENSACAP00000015078	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	APOA4	ENSACAP00000014992	ENSACAP00000001607	ATP binding cassette subfamily G member 5.	Apolipoprotein A4.	0.430
ABCG5	NR1H2	ENSACAP00000014992	ENSACAP00000012374	ATP binding cassette subfamily G member 5.	Nuclear receptor subfamily 1 group H member 2.	0.423
ABCG5	NR1H3	ENSACAP00000014992	ENSACAP00000002908	ATP binding cassette subfamily G member 5.	Nuclear receptor subfamily 1 group H member 3.	0.423
ABCG5	apoe	ENSACAP00000014992	ENSACAP00000018466	ATP binding cassette subfamily G member 5.	Uncharacterized protein.	0.542
ABCG8	ABCG5	ENSACAP00000015078	ENSACAP00000014992	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	apoe	ENSACAP00000015078	ENSACAP00000018466	ATP binding cassette subfamily G member 8.	Uncharacterized protein.	0.523
ACSL1	ACSL5	ENSACAP00000002577	ENSACAP00000009720	Acyl-CoA synthetase long chain family member 1.	Acyl-CoA synthetase long chain family member 5.	0.607
ACSL1	SCP2	ENSACAP00000002577	ENSACAP00000008417	Acyl-CoA synthetase long chain family member 1.	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.680
ACSL5	ACSL1	ENSACAP00000009720	ENSACAP00000002577	Acyl-CoA synthetase long chain family member 5.	Acyl-CoA synthetase long chain family member 1.	0.607
ACSL5	SCP2	ENSACAP00000009720	ENSACAP00000008417	Acyl-CoA synthetase long chain family member 5.	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.680