STRINGSTRING
NAXE NAXE PCSK9 PCSK9 SYK SYK GPS2 GPS2 EPRS1 EPRS1 APOA4 APOA4 nfkbia nfkbia ITGAV ITGAV TNFSF11 TNFSF11 ARV1 ARV1 ADIPOQ ADIPOQ ABCG4 ABCG4 ACSL1 ACSL1 GALR1 GALR1 TNFRSF11A TNFRSF11A C1QTNF1 C1QTNF1 BMP6 BMP6 NR1H3 NR1H3 ABCG1 ABCG1 LOC100555537 LOC100555537 PRELID1 PRELID1 C1QTNF8 C1QTNF8 CAV1 CAV1 LPCAT3 LPCAT3 EEPD1 EEPD1 PLA2G6 PLA2G6 SCP2 SCP2 PTGES PTGES LOC100567117 LOC100567117 LOC100561467 LOC100561467 LOC100567205 LOC100567205 ACSL5 ACSL5 LOC100568171 LOC100568171 DAB2 DAB2 SIRT1 SIRT1 POMC POMC CAV3 CAV3 PLA2R1 PLA2R1 NR1H2 NR1H2 SPP1 SPP1 yjefn3 yjefn3 PTCH1 PTCH1 LOC100561963 LOC100561963 Ldlrap1 Ldlrap1 PLTP PLTP NUS1 NUS1 LAMTOR1 LAMTOR1 CRY2 CRY2 SURF4 SURF4 ABCG5 ABCG5 TMF1 TMF1 CRY1 CRY1 ABCG8 ABCG8 ABCA12 ABCA12 PODNL1 PODNL1 ENPP7 ENPP7 C1QTNF6 C1QTNF6 CRH CRH itgb3 itgb3 LOC100567765 LOC100567765 TTC39B TTC39B P2RX7 P2RX7 apoe apoe PODN PODN FASLG FASLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (690 aa)
SYKTyrosine-protein kinase. (634 aa)
GPS2G protein pathway suppressor 2. (136 aa)
EPRS1Glutamyl-prolyl-tRNA synthetase. (1524 aa)
APOA4Apolipoprotein A4. (369 aa)
nfkbiaANK_REP_REGION domain-containing protein. (310 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1041 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (234 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (252 aa)
ABCG4ATP binding cassette subfamily G member 4. (580 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
TNFRSF11ATNF receptor superfamily member 11a. (657 aa)
C1QTNF1C1q and TNF related 1. (272 aa)
BMP6Bone morphogenetic protein 6. (299 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (408 aa)
ABCG1ATP binding cassette subfamily G member 1. (666 aa)
LOC100555537FAD_binding_7 domain-containing protein. (392 aa)
PRELID1PRELI domain containing 1. (216 aa)
C1QTNF8C1q and TNF related 8. (199 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (476 aa)
EEPD1Endonuclease/exonuclease/phosphatase family domain containing 1. (556 aa)
PLA2G6Phospholipase A2 group VI. (663 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa)
PTGESProstaglandin E synthase. (146 aa)
LOC100567117Uncharacterized protein. (270 aa)
LOC100561467Uncharacterized protein. (441 aa)
LOC100567205G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (696 aa)
LOC100568171Phospholipase A(2). (124 aa)
DAB2DAB adaptor protein 2. (638 aa)
SIRT1Sirtuin 1. (634 aa)
POMCProopiomelanocortin. (240 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (157 aa)
PLA2R1Phospholipase A2 receptor 1. (1473 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (436 aa)
SPP1Secreted phosphoprotein 1. (289 aa)
yjefn3YjeF N-terminal domain-containing protein. (235 aa)
PTCH1Patched 1. (1047 aa)
LOC100561963Photolyase/cryptochrome alpha/beta domain-containing protein. (554 aa)
Ldlrap1PID domain-containing protein. (64 aa)
PLTPPhospholipid transfer protein. (489 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (292 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
CRY2Cryptochrome circadian regulator 2. (586 aa)
SURF4SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (677 aa)
ABCG5ATP binding cassette subfamily G member 5. (619 aa)
TMF1TATA element modulatory factor 1. (1098 aa)
CRY1Cryptochrome circadian regulator 1. (621 aa)
ABCG8ATP binding cassette subfamily G member 8. (675 aa)
ABCA12ATP binding cassette subfamily A member 12. (2593 aa)
PODNL1Podocan like 1. (584 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (417 aa)
C1QTNF6C1q and TNF related 6. (261 aa)
CRHCorticotropin releasing hormone. (202 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (585 aa)
LOC100567765Uncharacterized protein. (528 aa)
TTC39BTetratricopeptide repeat domain 39B. (554 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (568 aa)
apoeUncharacterized protein. (252 aa)
PODNPodocan. (597 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (261 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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