STRINGSTRING
tmem249 tmem249 LOC100555851 LOC100555851 CACNA1E CACNA1E CACNG4 CACNG4 CACNG1 CACNG1 PKD2L1 PKD2L1 MCU MCU trpv5 trpv5 MICU1 MICU1 CATSPER3 CATSPER3 LOC103280541 LOC103280541 H9G624_ANOCA H9G624_ANOCA LOC100557448 LOC100557448 AKAP6 AKAP6 MICU2 MICU2 CATSPER4 CATSPER4 SMDT1 SMDT1 CACNB3 CACNB3 H9GVG2_ANOCA H9GVG2_ANOCA LOC103282539 LOC103282539 catsperd catsperd H9GSM9_ANOCA H9GSM9_ANOCA H9GRJ6_ANOCA H9GRJ6_ANOCA CACNG8 CACNG8 TRPC4 TRPC4 CACNB1 CACNB1 CACNG6 CACNG6 CACNG2 CACNG2 H9GMB4_ANOCA H9GMB4_ANOCA EFCAB9 EFCAB9 TRPC5 TRPC5 CACNA1F CACNA1F CACNA2D1 CACNA2D1 MCUB MCUB cacnb4 cacnb4 LOC100560693 LOC100560693 CACNA1C CACNA1C CACNA1B CACNA1B CACNA2D3 CACNA2D3 G1KLC7_ANOCA G1KLC7_ANOCA FKBP1B FKBP1B Cacna1d Cacna1d PTPA PTPA cacna2d4 cacna2d4 CACNA1S CACNA1S CATSPERB CATSPERB H9GEX9_ANOCA H9GEX9_ANOCA Catsper1 Catsper1 LOC100552814 LOC100552814 LOC100566195 LOC100566195 CACHD1 CACHD1 fkbp1a fkbp1a CACNA1I CACNA1I G1K855_ANOCA G1K855_ANOCA CACNA2D2 CACNA2D2 Pkd1 Pkd1 MICU3 MICU3 CACNB2 CACNB2 CACNA1G CACNA1G Cacna1a Cacna1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tmem249Uncharacterized protein. (178 aa)
LOC100555851Ion_trans domain-containing protein. (483 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2415 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (308 aa)
CACNG1Calcium voltage-gated channel auxiliary subunit gamma 1. (227 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (688 aa)
MCUMitochondrial calcium uniporter. (351 aa)
trpv5ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (726 aa)
MICU1Mitochondrial calcium uptake 1. (485 aa)
CATSPER3Cation channel sperm associated 3. (368 aa)
LOC103280541Uncharacterized protein. (1136 aa)
H9G624_ANOCAUncharacterized protein. (253 aa)
LOC100557448Uncharacterized protein. (1093 aa)
AKAP6A-kinase anchoring protein 6. (2331 aa)
MICU2Mitochondrial calcium uptake 2. (452 aa)
CATSPER4Cation channel sperm associated 4. (408 aa)
SMDT1Single-pass membrane protein with aspartate rich tail 1. (105 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (561 aa)
H9GVG2_ANOCAUncharacterized protein. (589 aa)
LOC103282539Uncharacterized protein. (227 aa)
catsperdUncharacterized protein. (768 aa)
H9GSM9_ANOCAUncharacterized protein. (429 aa)
H9GRJ6_ANOCAUncharacterized protein. (763 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (368 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (976 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (620 aa)
CACNG6Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (259 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
H9GMB4_ANOCAIon_trans domain-containing protein. (182 aa)
EFCAB9EF-hand calcium binding domain 9. (218 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (988 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2073 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1113 aa)
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (343 aa)
cacnb4SH3 domain-containing protein. (502 aa)
LOC100560693Uncharacterized protein. (362 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2065 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2188 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1098 aa)
G1KLC7_ANOCACa_chan_IQ domain-containing protein. (872 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1136 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (285 aa)
cacna2d4VWFA domain-containing protein. (501 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1843 aa)
CATSPERBCation channel sperm associated auxiliary subunit beta. (1096 aa)
H9GEX9_ANOCAUncharacterized protein. (3670 aa)
Catsper1Ion_trans domain-containing protein. (360 aa)
LOC100552814Ion_trans domain-containing protein. (739 aa)
LOC100566195ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (733 aa)
CACHD1Cache domain containing 1. (1285 aa)
fkbp1aPeptidylprolyl isomerase. (81 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2127 aa)
G1K855_ANOCAVGCC_alpha2 domain-containing protein. (273 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (694 aa)
Pkd1Uncharacterized protein. (816 aa)
MICU3Mitochondrial calcium uptake family member 3. (558 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (645 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2312 aa)
Cacna1aIon_trans domain-containing protein. (204 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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