(14 nodes) Ciliary rootlet network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCDC151	Coiled-coil domain containing 151. (551 aa)
	RPGRIP1L	RPGRIP1 like. (1262 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
	LOC103282500	TPR_REGION domain-containing protein. (204 aa)
	APP	Amyloid beta precursor protein. (776 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (965 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (454 aa)
	rab28	Uncharacterized protein. (96 aa)
	KIF5A	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1103 aa)
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (952 aa)
	crocc	Uncharacterized protein. (612 aa)
	CROCC2	Ciliary rootlet coiled-coil, rootletin family member 2. (1843 aa)
	LOC100558120	Uncharacterized protein. (1179 aa)
	pjvk	Gasdermin domain-containing protein. (354 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	LOC103282500	ENSACAP00000014509	ENSACAP00000014528	Amyloid beta precursor protein.	TPR_REGION domain-containing protein.	0.606
APP	PSEN1	ENSACAP00000014509	ENSACAP00000015950	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.968
APP	PSEN2	ENSACAP00000014509	ENSACAP00000006363	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.883
KIF5A	KIF5B	ENSACAP00000022871	ENSACAP00000007080	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.903
KIF5A	KIF5C	ENSACAP00000022871	ENSACAP00000003224	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.902
KIF5A	LOC103282500	ENSACAP00000022871	ENSACAP00000014528	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	TPR_REGION domain-containing protein.	0.586
KIF5B	KIF5A	ENSACAP00000007080	ENSACAP00000022871	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.903
KIF5B	KIF5C	ENSACAP00000007080	ENSACAP00000003224	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.901
KIF5B	LOC103282500	ENSACAP00000007080	ENSACAP00000014528	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	TPR_REGION domain-containing protein.	0.586
KIF5C	KIF5A	ENSACAP00000003224	ENSACAP00000022871	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.902
KIF5C	KIF5B	ENSACAP00000003224	ENSACAP00000007080	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.901
KIF5C	LOC103282500	ENSACAP00000003224	ENSACAP00000014528	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	TPR_REGION domain-containing protein.	0.586
LOC103282500	APP	ENSACAP00000014528	ENSACAP00000014509	TPR_REGION domain-containing protein.	Amyloid beta precursor protein.	0.606
LOC103282500	KIF5A	ENSACAP00000014528	ENSACAP00000022871	TPR_REGION domain-containing protein.	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.586
LOC103282500	KIF5B	ENSACAP00000014528	ENSACAP00000007080	TPR_REGION domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.586
LOC103282500	KIF5C	ENSACAP00000014528	ENSACAP00000003224	TPR_REGION domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.586
PSEN1	APP	ENSACAP00000015950	ENSACAP00000014509	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Amyloid beta precursor protein.	0.968
PSEN1	PSEN2	ENSACAP00000015950	ENSACAP00000006363	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.999
PSEN2	APP	ENSACAP00000006363	ENSACAP00000014509	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Amyloid beta precursor protein.	0.883
PSEN2	PSEN1	ENSACAP00000006363	ENSACAP00000015950	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.999