STRINGSTRING
DDB1 DDB1 PCGF6 PCGF6 BCOR BCOR RNF168 RNF168 PCGF1 PCGF1 PCGF3 PCGF3 RNF2 RNF2 PCGF5 PCGF5 RING1 RING1 LOC100567594 LOC100567594 TRIM37 TRIM37 PCGF2 PCGF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDB1Damage specific DNA binding protein 1. (1140 aa)
PCGF6Polycomb group ring finger 6. (198 aa)
BCORBCL6 corepressor. (1721 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (577 aa)
PCGF1Polycomb group ring finger 1. (187 aa)
PCGF3Polycomb group ring finger 3. (242 aa)
RNF2Ring finger protein 2. (336 aa)
PCGF5Polycomb group ring finger 5. (256 aa)
RING1Ring finger protein 1. (346 aa)
LOC100567594RING-type domain-containing protein. (323 aa)
TRIM37Tripartite motif containing 37. (967 aa)
PCGF2Polycomb group ring finger 2. (357 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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