STRINGSTRING
SASH3 SASH3 IL7R IL7R LFNG LFNG CARD11 CARD11 TBC1D10C TBC1D10C LEF1 LEF1 CLCF1 CLCF1 DCAF1 DCAF1 LOC100568039 LOC100568039 LOC100566290 LOC100566290 POU2AF1 POU2AF1 PTPRC PTPRC BLNK BLNK atm atm EP300 EP300 RAG1 RAG1 RAG2 RAG2 EXOSC3 EXOSC3 PHB PHB TXLNA TXLNA DOCK10 DOCK10 LRRC8A LRRC8A CDH17 CDH17 EXO1 EXO1 IKZF3 IKZF3 gon4l gon4l NHEJ1 NHEJ1 LOC100556408 LOC100556408 KIAA1841 KIAA1841 DLL1 DLL1 DEF6 DEF6 RNF8 RNF8 DNAJB9 DNAJB9 GPS2 GPS2 ITM2A ITM2A SYK SYK dll3 dll3 LOC103279952 LOC103279952 H9GT41_ANOCA H9GT41_ANOCA G1KX99_ANOCA G1KX99_ANOCA CD40LG CD40LG Mfng Mfng LOC103277687 LOC103277687 LOC103282543 LOC103282543 nfam1 nfam1 cd19 cd19 TPD52 TPD52 ercc1 ercc1 R4GCW4_ANOCA R4GCW4_ANOCA MALT1 MALT1 LOC103277689 LOC103277689 ATAD5 ATAD5 G1KVV2_ANOCA G1KVV2_ANOCA G1KV77_ANOCA G1KV77_ANOCA BANK1 BANK1 G1KUT7_ANOCA G1KUT7_ANOCA gpr183 gpr183 BCL2 BCL2 G1KU56_ANOCA G1KU56_ANOCA LOC103277688 LOC103277688 BAX BAX AICDA AICDA TSHR TSHR CXCR5 CXCR5 SP3 SP3 lyl1 lyl1 BATF BATF BAK1 BAK1 RNF168 RNF168 CD180 CD180 mfng mfng RASGRP1 RASGRP1 ZBTB1 ZBTB1 LGALS1 LGALS1 ITFG2 ITFG2 NTRK1 NTRK1 cd79a cd79a LIG4 LIG4 TNFSF13B TNFSF13B MSH6 MSH6 MSH2 MSH2 CEBPG CEBPG PTPN2 PTPN2 PIK3CD PIK3CD LOC100553447 LOC100553447 FNIP1 FNIP1 G1KLA4_ANOCA G1KLA4_ANOCA H9GHU4_ANOCA H9GHU4_ANOCA rabl3 rabl3 SKAP2 SKAP2 NBN NBN KIT KIT MLH1 MLH1 LOC100564157 LOC100564157 FLT3 FLT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SASH3SAM and SH3 domain containing 3. (378 aa)
IL7RInterleukin 7 receptor. (476 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (344 aa)
CARD11Caspase recruitment domain family member 11. (1089 aa)
TBC1D10CTBC1 domain family member 10C. (371 aa)
LEF1Lymphoid enhancer binding factor 1. (403 aa)
CLCF1Cardiotrophin like cytokine factor 1. (228 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1493 aa)
LOC100568039Galectin. (136 aa)
LOC100566290Galectin. (130 aa)
POU2AF1POU class 2 homeobox associating factor 1. (260 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1269 aa)
BLNKB cell linker. (590 aa)
atmUncharacterized protein; Belongs to the PI3/PI4-kinase family. (423 aa)
EP300E1A binding protein p300. (2484 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1046 aa)
RAG2Recombination activating 2. (530 aa)
EXOSC3Exosome component 3. (263 aa)
PHBProhibitin. (275 aa)
TXLNATaxilin alpha. (411 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2180 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
CDH17Cadherin 17. (833 aa)
EXO1Exonuclease 1. (810 aa)
IKZF3IKAROS family zinc finger 3. (511 aa)
gon4lUncharacterized protein. (1613 aa)
NHEJ1Non-homologous end joining factor 1. (309 aa)
LOC100556408FAT domain-containing protein. (2448 aa)
KIAA1841KIAA1841. (719 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (870 aa)
DEF6DEF6 guanine nucleotide exchange factor. (702 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (216 aa)
GPS2G protein pathway suppressor 2. (136 aa)
ITM2AIntegral membrane protein 2A. (260 aa)
SYKTyrosine-protein kinase. (634 aa)
dll3Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (613 aa)
LOC103279952Uncharacterized protein. (905 aa)
H9GT41_ANOCAUncharacterized protein. (189 aa)
G1KX99_ANOCAUncharacterized protein. (193 aa)
CD40LGCD40 ligand; Belongs to the tumor necrosis factor family. (301 aa)
MfngUncharacterized protein. (106 aa)
LOC103277687Uncharacterized protein. (178 aa)
LOC103282543Uncharacterized protein. (158 aa)
nfam1Uncharacterized protein. (238 aa)
cd19Ig-like domain-containing protein. (515 aa)
TPD52Uncharacterized protein. (188 aa)
ercc1Uncharacterized protein. (297 aa)
R4GCW4_ANOCAIg-like domain-containing protein. (336 aa)
MALT1MALT1 paracaspase. (731 aa)
LOC103277689Uncharacterized protein. (180 aa)
ATAD5ATPase family AAA domain containing 5. (1748 aa)
G1KVV2_ANOCAUncharacterized protein. (149 aa)
G1KV77_ANOCAUncharacterized protein. (46 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (877 aa)
G1KUT7_ANOCAUncharacterized protein. (205 aa)
gpr183G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
BCL2BCL2 apoptosis regulator. (170 aa)
G1KU56_ANOCAUncharacterized protein. (186 aa)
LOC103277688Uncharacterized protein. (192 aa)
BAXBCL2 associated X, apoptosis regulator. (207 aa)
AICDAActivation induced cytidine deaminase. (199 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (704 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (369 aa)
SP3Sp3 transcription factor. (786 aa)
lyl1BHLH domain-containing protein. (263 aa)
BATFBasic leucine zipper ATF-like transcription factor. (127 aa)
BAK1BCL2 antagonist/killer 1. (214 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (577 aa)
CD180CD180 molecule. (662 aa)
mfngUncharacterized protein. (212 aa)
RASGRP1RAS guanyl releasing protein 1. (729 aa)
ZBTB1Zinc finger and BTB domain containing 1. (708 aa)
LGALS1Galectin. (135 aa)
ITFG2Integrin alpha FG-GAP repeat containing 2. (469 aa)
NTRK1Tyrosine-protein kinase receptor. (800 aa)
cd79aIg-like domain-containing protein. (237 aa)
LIG4DNA ligase. (906 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (253 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1317 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (953 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (422 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1047 aa)
LOC100553447Galectin. (135 aa)
FNIP1Folliculin interacting protein 1. (1145 aa)
G1KLA4_ANOCASEFIR domain-containing protein. (540 aa)
H9GHU4_ANOCAUncharacterized protein. (267 aa)
rabl3Uncharacterized protein. (236 aa)
SKAP2Src kinase associated phosphoprotein 2. (345 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (761 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (946 aa)
MLH1MutL homolog 1. (746 aa)
LOC100564157Prohibitin. (272 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1005 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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